KR870010079A - 면역촉진 활성을 갖는 트리펩티드 - Google Patents

면역촉진 활성을 갖는 트리펩티드 Download PDF

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Publication number
KR870010079A
KR870010079A KR870003454A KR870003454A KR870010079A KR 870010079 A KR870010079 A KR 870010079A KR 870003454 A KR870003454 A KR 870003454A KR 870003454 A KR870003454 A KR 870003454A KR 870010079 A KR870010079 A KR 870010079A
Authority
KR
South Korea
Prior art keywords
tripeptide
immunostimulatory activity
glu
lys
arg
Prior art date
Application number
KR870003454A
Other languages
English (en)
Inventor
브루네티 브루네토
프라다 마르코
Original Assignee
로베르토 비안치
엘렌 인더스트리아 파마슈티카 에스. 페. 아
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 로베르토 비안치, 엘렌 인더스트리아 파마슈티카 에스. 페. 아 filed Critical 로베르토 비안치
Publication of KR870010079A publication Critical patent/KR870010079A/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0815—Tripeptides with the first amino acid being basic
    • C07K5/0817—Tripeptides with the first amino acid being basic the first amino acid being Arg
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

내용 없음

Description

면약촉진 활성을 갖는 트리펩티드
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
본 도면은 트리펩티드의 HPLC 프로파일을 나타내는 스펙트럼도

Claims (5)

  1. 다음 구조를 갖는 L-Arg(아르기닌), L-Lys(리신) 및 L-Glu(글루탐산)으로 구성되는 트리펩티드 : Arg-Lys-Glu
  2. 제1항에 있어서, 면역촉진 활성을 갖는 트리펩티드.
  3. 제1항에 있어서, 면역 시스템의 제1 및 제2결함에 의해 유발되는 병에 약제로서 가능한 치료 용도를 갖는 트리펩티드.
  4. 제1항에 있어서, 비경구 및 경구투여한 후 면역촉진 활성을 발휘할 수 있는 트리펩티드.
  5. 제3항에 따른 약제로서 가능한 용도를 갖는 초산염, 트리플루오로초산염, 염화수소염, 황산염과 같은 트리펩티드의 제약에 수용할 수 있는 염.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR870003454A 1986-04-09 1987-04-09 면역촉진 활성을 갖는 트리펩티드 KR870010079A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT20026/86A IT1188645B (it) 1986-04-09 1986-04-09 Tripeptide ad attivita' immunostimolante
IT20026A/86 1986-04-09

Publications (1)

Publication Number Publication Date
KR870010079A true KR870010079A (ko) 1987-11-30

Family

ID=11163216

Family Applications (1)

Application Number Title Priority Date Filing Date
KR870003454A KR870010079A (ko) 1986-04-09 1987-04-09 면역촉진 활성을 갖는 트리펩티드

Country Status (19)

Country Link
US (1) US4874844A (ko)
JP (1) JPH0645636B2 (ko)
KR (1) KR870010079A (ko)
AR (1) AR243202A1 (ko)
AT (1) ATA88487A (ko)
AU (1) AU594449B2 (ko)
BE (1) BE1001157A4 (ko)
CA (1) CA1315478C (ko)
CH (1) CH678328A5 (ko)
DE (1) DE3712090A1 (ko)
ES (1) ES2005143A6 (ko)
FR (1) FR2597106B1 (ko)
GB (1) GB2189490B (ko)
GR (1) GR870567B (ko)
IE (1) IE59805B1 (ko)
IT (1) IT1188645B (ko)
NL (1) NL8700826A (ko)
SE (1) SE8701456L (ko)
TR (1) TR23367A (ko)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1188645B (it) * 1986-04-09 1988-01-20 Ellem Ind Farmaceutica Tripeptide ad attivita' immunostimolante
HUT46044A (en) * 1986-11-21 1988-09-28 Richter Gedeon Vegyeszet Process for producing immunstimulant peptides inhibiting multiplication of leukaemic cells and pharmaceutics comprising same
DK15888D0 (da) * 1988-01-14 1988-01-14 Carlsberg Biotechnology Ltd Enzymatisk fremgangsmaade til fremstilling af immunmodulerende pentapeptider samt mellemprodukter til brug ved fremgangsmaaden
IT1226552B (it) * 1988-07-29 1991-01-24 Ellem Ind Farmaceutica Peptidi immunostimolanti.
US5225400A (en) * 1988-07-29 1993-07-06 Ellem Industria Farmaceutica S.R.L. Immunostimulating peptides, a process for their preparation and pharmaceutical compositions containing them

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU185263B (en) * 1981-06-12 1984-12-28 Richter Gedeon Vegyeszet Process for producing peptides effective on the immuncontroll analogous with the tp5
IT1188645B (it) * 1986-04-09 1988-01-20 Ellem Ind Farmaceutica Tripeptide ad attivita' immunostimolante

Also Published As

Publication number Publication date
DE3712090C2 (ko) 1991-06-13
IT1188645B (it) 1988-01-20
FR2597106A1 (fr) 1987-10-16
ATA88487A (de) 1996-05-15
AR243202A1 (es) 1993-07-30
AU7118387A (en) 1987-10-15
SE8701456L (sv) 1987-10-10
NL8700826A (nl) 1987-11-02
DE3712090A1 (de) 1987-10-15
CH678328A5 (ko) 1991-08-30
BE1001157A4 (fr) 1989-08-01
GB8708491D0 (en) 1987-05-13
IT8620026A0 (it) 1986-04-09
GR870567B (en) 1987-08-12
AU594449B2 (en) 1990-03-08
GB2189490B (en) 1990-02-14
US4874844A (en) 1989-10-17
JPH0645636B2 (ja) 1994-06-15
FR2597106B1 (fr) 1990-07-13
GB2189490A (en) 1987-10-28
IT8620026A1 (it) 1987-10-09
CA1315478C (en) 1993-03-30
JPS62265300A (ja) 1987-11-18
TR23367A (tr) 1989-12-28
IE870879L (en) 1987-10-09
IE59805B1 (en) 1994-04-06
SE8701456D0 (sv) 1987-04-07
ES2005143A6 (es) 1989-03-01

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