KR870001569B1 - 피롤리딘 유도체의 제조방법 - Google Patents

피롤리딘 유도체의 제조방법 Download PDF

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Publication number
KR870001569B1
KR870001569B1 KR1019850000850A KR850000850A KR870001569B1 KR 870001569 B1 KR870001569 B1 KR 870001569B1 KR 1019850000850 A KR1019850000850 A KR 1019850000850A KR 850000850 A KR850000850 A KR 850000850A KR 870001569 B1 KR870001569 B1 KR 870001569B1
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KR
South Korea
Prior art keywords
compound
formula
reaction
iii
carried out
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
KR1019850000850A
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English (en)
Korean (ko)
Other versions
KR860006441A (ko
Inventor
김돈기
이기홍
김지한
Original Assignee
보령제약 주식회사
김승호
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 보령제약 주식회사, 김승호 filed Critical 보령제약 주식회사
Priority to KR1019850000850A priority Critical patent/KR870001569B1/ko
Priority to DE19853538747 priority patent/DE3538747A1/de
Priority to ES548744A priority patent/ES8606269A1/es
Priority to JP60282703A priority patent/JPS61183263A/ja
Priority to GB08602782A priority patent/GB2170806B/en
Priority to FR8601839A priority patent/FR2577222B1/fr
Publication of KR860006441A publication Critical patent/KR860006441A/ko
Application granted granted Critical
Publication of KR870001569B1 publication Critical patent/KR870001569B1/ko
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
KR1019850000850A 1985-02-11 1985-02-11 피롤리딘 유도체의 제조방법 Expired KR870001569B1 (ko)

Priority Applications (6)

Application Number Priority Date Filing Date Title
KR1019850000850A KR870001569B1 (ko) 1985-02-11 1985-02-11 피롤리딘 유도체의 제조방법
DE19853538747 DE3538747A1 (de) 1985-02-11 1985-10-31 Verfahren zur herstellung von pyrrolidin-derivaten
ES548744A ES8606269A1 (es) 1985-02-11 1985-11-11 Procedimiento para preparar un derivado de pirrolidina
JP60282703A JPS61183263A (ja) 1985-02-11 1985-12-16 ピロリジン誘導体の製造方法
GB08602782A GB2170806B (en) 1985-02-11 1986-02-05 1-(3 mercapto-2-methylpropionyl)-l-proline, precursors thereof and processes for their preparation
FR8601839A FR2577222B1 (fr) 1985-02-11 1986-02-11 Procede pour la preparation de l'acide 1-(3-mercapto-25-methylpropionyl)-pyrrolidine-(25)-carboxylique

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019850000850A KR870001569B1 (ko) 1985-02-11 1985-02-11 피롤리딘 유도체의 제조방법

Publications (2)

Publication Number Publication Date
KR860006441A KR860006441A (ko) 1986-09-11
KR870001569B1 true KR870001569B1 (ko) 1987-09-04

Family

ID=19239706

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019850000850A Expired KR870001569B1 (ko) 1985-02-11 1985-02-11 피롤리딘 유도체의 제조방법

Country Status (6)

Country Link
JP (1) JPS61183263A (enrdf_load_stackoverflow)
KR (1) KR870001569B1 (enrdf_load_stackoverflow)
DE (1) DE3538747A1 (enrdf_load_stackoverflow)
ES (1) ES8606269A1 (enrdf_load_stackoverflow)
FR (1) FR2577222B1 (enrdf_load_stackoverflow)
GB (1) GB2170806B (enrdf_load_stackoverflow)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU208954B (en) * 1990-09-21 1994-02-28 Egyt Gyogyszervegyeszeti Gyar Process for producing 1-(3-mercapto-(2s)-methyl-1-oxo-propyl)-l-prolyn
US5237073A (en) * 1988-08-26 1993-08-17 Sepracor, Inc. Derivatives and precursors of captopril and its analogues
EP0432204A4 (en) * 1988-08-26 1992-08-12 Sepracor, Inc. Derivatives and precursors of captopril and its analogues
KR940005014B1 (ko) * 1991-11-07 1994-06-09 보령제약 주식회사 피롤리딘카르복실산 유도체의 제조방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU509899B2 (en) * 1976-02-13 1980-05-29 E.R. Squibb & Sons, Inc. Proline derivatives and related compounds
US4046889A (en) * 1976-02-13 1977-09-06 E. R. Squibb & Sons, Inc. Azetidine-2-carboxylic acid derivatives
US4192945A (en) * 1978-12-07 1980-03-11 E. R. Squibb & Sons, Inc. Process for preparing proline and homoproline derivatives
GB2065643B (en) * 1979-12-13 1983-08-24 Kanegafuchi Chemical Ind Optically active n-mercaptoalkanoylamino acids
HU184082B (en) * 1979-12-29 1984-06-28 Egyt Gyogyszervegyeszeti Gyar Process for preparing 1-3-/3mercapto-/2s/-methyl-propinyl/-pyrrolidine-/2s/-carboxylic acid
JPS58124764A (ja) * 1982-01-20 1983-07-25 Kanegafuchi Chem Ind Co Ltd 光学活性チオ−ル化合物の製造法

Also Published As

Publication number Publication date
GB8602782D0 (en) 1986-03-12
DE3538747C2 (enrdf_load_stackoverflow) 1988-08-18
GB2170806A (en) 1986-08-13
JPS61183263A (ja) 1986-08-15
GB2170806B (en) 1988-08-03
FR2577222A1 (fr) 1986-08-14
ES548744A0 (es) 1986-04-01
KR860006441A (ko) 1986-09-11
DE3538747A1 (de) 1986-08-14
FR2577222B1 (fr) 1987-12-24
ES8606269A1 (es) 1986-04-01

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