KR850006188A - 스피로-3-헤테로-아졸리딘디온의 제조방법 - Google Patents

스피로-3-헤테로-아졸리딘디온의 제조방법 Download PDF

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Publication number
KR850006188A
KR850006188A KR1019850001848A KR850001848A KR850006188A KR 850006188 A KR850006188 A KR 850006188A KR 1019850001848 A KR1019850001848 A KR 1019850001848A KR 850001848 A KR850001848 A KR 850001848A KR 850006188 A KR850006188 A KR 850006188A
Authority
KR
South Korea
Prior art keywords
hydrogen
carbon atoms
compound
formula
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1019850001848A
Other languages
English (en)
Korean (ko)
Inventor
앤드류리핀스키 크리스토퍼
Original Assignee
윌리암 지. 맥크리
화이자 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 윌리암 지. 맥크리, 화이자 인코포레이티드 filed Critical 윌리암 지. 맥크리
Publication of KR850006188A publication Critical patent/KR850006188A/ko
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/80—Two oxygen atoms, e.g. hydantoin with hetero atoms or acyl radicals directly attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
KR1019850001848A 1984-03-23 1985-03-21 스피로-3-헤테로-아졸리딘디온의 제조방법 Ceased KR850006188A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59301284A 1984-03-23 1984-03-23
US593012 2000-06-13

Publications (1)

Publication Number Publication Date
KR850006188A true KR850006188A (ko) 1985-10-02

Family

ID=24372993

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019850001848A Ceased KR850006188A (ko) 1984-03-23 1985-03-21 스피로-3-헤테로-아졸리딘디온의 제조방법

Country Status (15)

Country Link
EP (1) EP0159143B1 (en:Method)
JP (1) JPS60209572A (en:Method)
KR (1) KR850006188A (en:Method)
AU (1) AU563668B2 (en:Method)
CA (1) CA1244443A (en:Method)
DE (1) DE3561198D1 (en:Method)
DK (1) DK131885A (en:Method)
ES (1) ES8606295A1 (en:Method)
FI (1) FI851170L (en:Method)
GR (1) GR850704B (en:Method)
HU (1) HU195783B (en:Method)
IL (1) IL74667A (en:Method)
PH (1) PH23921A (en:Method)
PL (1) PL145198B1 (en:Method)
PT (1) PT80145B (en:Method)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4575507A (en) * 1985-05-29 1986-03-11 Pfizer Inc. Spiro-imidazolidines as aldose reductase inhibitors and their pharmaceutical use
GB2355264A (en) 1999-09-30 2001-04-18 Merck & Co Inc Spirohydantoin derivatives useful as alpha 1a adrenoceptor antagonists
ATE516803T1 (de) 2003-03-14 2011-08-15 Merck Sharp & Dohme Aryl-spirohydantoin-cgrp-rezeptor-antagonisten
US7750010B2 (en) * 2004-09-13 2010-07-06 Merck Sharp & Dohme Corp. Tricyclic anilide spirohydantion CGRP receptor antagonists
US8071770B2 (en) 2005-11-18 2011-12-06 Merck Sharp & Dohme Corp. Spirohydantoin aryl CGRP receptor antagonists
CN111732545B (zh) * 2020-06-08 2023-03-10 华侨大学 一种2,3-二氢螺[咪唑-4,1′-茚]类化合物及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4117230A (en) * 1976-10-18 1978-09-26 Pfizer Inc. Hydantoin derivatives as therapeutic agents
US4130714A (en) * 1977-05-23 1978-12-19 Pfizer Inc. Hydantoin therapeutic agents
US4181729A (en) * 1979-03-21 1980-01-01 Pfizer Inc. Phenyl or phenoxy substituted spiro-imidazolidinedione derivatives
US4226875A (en) * 1979-04-02 1980-10-07 Pfizer Inc. Novel spiro-oxazolidinediones
ES515751A0 (es) * 1981-10-13 1983-10-16 Pfizer "un procedimiento por analogia para la preparacion de derivados de espiro-oxindol-oxazolidindiona".
ZA832679B (en) * 1982-05-07 1983-12-28 Ici Plc Indoline derivatives
US4556670A (en) * 1982-12-06 1985-12-03 Pfizer Inc. Spiro-3-hetero-azolones for treatment of diabetic complications

Also Published As

Publication number Publication date
CA1244443A (en) 1988-11-08
FI851170A0 (fi) 1985-03-22
EP0159143B1 (en) 1987-12-16
PL252487A1 (en) 1985-10-08
AU4025185A (en) 1985-09-26
EP0159143A1 (en) 1985-10-23
AU563668B2 (en) 1987-07-16
FI851170A7 (fi) 1985-09-24
ES8606295A1 (es) 1986-04-16
PL145198B1 (en) 1988-08-31
HUT37603A (en) 1986-01-23
GR850704B (en:Method) 1985-07-19
DE3561198D1 (en) 1988-01-28
PH23921A (en) 1990-01-23
ES541450A0 (es) 1986-04-16
PT80145B (en) 1987-03-23
JPS60209572A (ja) 1985-10-22
FI851170L (fi) 1985-09-24
IL74667A0 (en) 1985-06-30
DK131885A (da) 1985-09-24
PT80145A (en) 1985-04-01
HU195783B (en) 1988-07-28
IL74667A (en) 1988-12-30
DK131885D0 (da) 1985-03-22

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Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19850321

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Patent event date: 19860927

Patent event code: PE09021S01D

E601 Decision to refuse application
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Patent event date: 19870311

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Patent event code: PE06012S01D

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Patent event code: PE06011S01I