KR830007518A - 약리적 활성 펩티드의 제조방법 - Google Patents

약리적 활성 펩티드의 제조방법 Download PDF

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Publication number
KR830007518A
KR830007518A KR1019810003971A KR810003971A KR830007518A KR 830007518 A KR830007518 A KR 830007518A KR 1019810003971 A KR1019810003971 A KR 1019810003971A KR 810003971 A KR810003971 A KR 810003971A KR 830007518 A KR830007518 A KR 830007518A
Authority
KR
South Korea
Prior art keywords
alanyl
methyl
tyrosyl
ethyl
glycyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1019810003971A
Other languages
English (en)
Korean (ko)
Inventor
데이빗 게젤첸 폴
데오도르 슈만 로버트
Original Assignee
아디 알·웨일
일라이 릴리 앤드 캄파니
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 아디 알·웨일, 일라이 릴리 앤드 캄파니 filed Critical 아디 알·웨일
Publication of KR830007518A publication Critical patent/KR830007518A/ko
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1027—Tetrapeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
KR1019810003971A 1980-10-20 1981-10-20 약리적 활성 펩티드의 제조방법 Ceased KR830007518A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/198,900 US4322340A (en) 1980-10-20 1980-10-20 Pharmacologically active peptides
US198,900 1980-10-20

Publications (1)

Publication Number Publication Date
KR830007518A true KR830007518A (ko) 1983-10-21

Family

ID=22735344

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019810003971A Ceased KR830007518A (ko) 1980-10-20 1981-10-20 약리적 활성 펩티드의 제조방법

Country Status (27)

Country Link
US (1) US4322340A (enExample)
EP (1) EP0050502B1 (enExample)
JP (1) JPS57108052A (enExample)
KR (1) KR830007518A (enExample)
AR (1) AR230046A1 (enExample)
AT (1) ATE6777T1 (enExample)
AU (1) AU547221B2 (enExample)
BG (1) BG36928A3 (enExample)
CA (1) CA1187871A (enExample)
DD (1) DD200798A5 (enExample)
DE (1) DE3162823D1 (enExample)
DK (1) DK461481A (enExample)
ES (1) ES8306713A1 (enExample)
FI (1) FI813198A7 (enExample)
GB (1) GB2085893B (enExample)
GR (1) GR75342B (enExample)
HU (1) HU185320B (enExample)
IE (1) IE52186B1 (enExample)
IL (1) IL64083A (enExample)
NZ (1) NZ198628A (enExample)
PH (1) PH17006A (enExample)
PL (1) PL131155B1 (enExample)
PT (1) PT73839B (enExample)
RO (1) RO83301B (enExample)
SU (1) SU1082319A3 (enExample)
YU (1) YU249081A (enExample)
ZA (1) ZA817063B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0076557B1 (en) * 1981-06-22 1985-11-13 Imperial Chemical Industries Plc Peptides and pseudopeptides in which the n terminus bears two substituents
US4448717A (en) * 1982-11-12 1984-05-15 Eli Lilly And Company Pharmacologically active peptides
US4473497A (en) * 1983-03-07 1984-09-25 Eli Lilly And Company Pharmacologically active peptides
DK134784A (da) * 1983-03-07 1984-09-08 Lilly Co Eli Farmakologisk virksomme tripeptid-derivater og fremgangsmaade til fremstilling deraf
US4510082A (en) * 1983-03-07 1985-04-09 Eli Lilly And Company Pharmacologically active peptides
US4495178A (en) * 1983-10-06 1985-01-22 G. D. Searle & Co. Enkephalin analogs
JPH0449298A (ja) * 1990-06-19 1992-02-18 Univ New York State 新規なエンケファリン誘導体および鎮痛剤
US5209930A (en) * 1990-12-10 1993-05-11 Rohm And Haas Company Preparation and use of n-iodopropargyl oxycarbonyl amino acid esters and derivatives as antimicrobial agents
US5952465A (en) * 1993-04-23 1999-09-14 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
US6258550B1 (en) 1993-04-23 2001-07-10 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
US5965698A (en) * 1993-04-23 1999-10-12 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein--protein interaction site
US5928896A (en) * 1993-04-23 1999-07-27 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein--protein interaction site
WO1994025482A1 (en) * 1993-04-23 1994-11-10 Evans Herbert J Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
US6084066A (en) * 1993-10-29 2000-07-04 Virginia Commonwealth University Polypetides that include conformation-constraining groups which flank a protein-protein interaction site

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1577115A (en) * 1976-07-27 1980-10-22 Reckitt & Colmann Prod Ltd Container closure units
CH619686A5 (en) * 1976-02-02 1980-10-15 Sandoz Ag Process for the preparation of novel peptides or peptide derivatives
FI770219A7 (enExample) * 1976-02-02 1977-08-03 Sandoz Ag
US4264491A (en) * 1977-10-03 1981-04-28 Eli Lilly And Company Analgesic compounds
US4265808A (en) * 1979-12-17 1981-05-05 Eli Lilly And Company Pharmacologically active peptides

Also Published As

Publication number Publication date
ES506316A0 (es) 1983-06-01
PH17006A (en) 1984-05-11
FI813198L (fi) 1982-04-21
DK461481A (da) 1982-04-21
RO83301B (ro) 1984-02-28
NZ198628A (en) 1985-01-31
PL233498A1 (enExample) 1982-05-24
US4322340A (en) 1982-03-30
AU547221B2 (en) 1985-10-10
IL64083A (en) 1985-03-31
YU249081A (en) 1983-12-31
GB2085893B (en) 1984-03-21
PT73839B (en) 1983-01-17
EP0050502A1 (en) 1982-04-28
ATE6777T1 (de) 1984-04-15
GB2085893A (en) 1982-05-06
AU7657481A (en) 1982-04-29
IE812442L (en) 1982-04-20
JPS57108052A (en) 1982-07-05
IE52186B1 (en) 1987-08-05
ES8306713A1 (es) 1983-06-01
DE3162823D1 (en) 1984-04-26
EP0050502B1 (en) 1984-03-21
SU1082319A3 (ru) 1984-03-23
HU185320B (en) 1985-01-28
GR75342B (enExample) 1984-07-13
CA1187871A (en) 1985-05-28
ZA817063B (en) 1983-05-25
RO83301A (ro) 1984-02-21
PL131155B1 (en) 1984-10-31
IL64083A0 (en) 1982-01-31
PT73839A (en) 1981-11-01
DD200798A5 (de) 1983-06-15
BG36928A3 (bg) 1985-02-15
AR230046A1 (es) 1984-02-29
FI813198A7 (fi) 1982-04-21

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Legal Events

Date Code Title Description
PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19811020

PG1501 Laying open of application
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 19850928

Patent event code: PE09021S01D

PE0601 Decision on rejection of patent

Patent event date: 19851205

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 19850928

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I