DE69932424D1 - Melanocortin 1 rezeptorselektive verbindungen - Google Patents

Melanocortin 1 rezeptorselektive verbindungen

Info

Publication number
DE69932424D1
DE69932424D1 DE69932424T DE69932424T DE69932424D1 DE 69932424 D1 DE69932424 D1 DE 69932424D1 DE 69932424 T DE69932424 T DE 69932424T DE 69932424 T DE69932424 T DE 69932424T DE 69932424 D1 DE69932424 D1 DE 69932424D1
Authority
DE
Germany
Prior art keywords
aminoacid
alkyl
compound
receptors
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69932424T
Other languages
English (en)
Other versions
DE69932424T2 (de
Inventor
Michael Szardenings
Ruta Muceniece
Ilze Mutule
Felikss Mutulis
Jarl Wikberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Action Pharma AS
Original Assignee
Action Pharma AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Action Pharma AS filed Critical Action Pharma AS
Application granted granted Critical
Publication of DE69932424D1 publication Critical patent/DE69932424D1/de
Publication of DE69932424T2 publication Critical patent/DE69932424T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/68—Melanocyte-stimulating hormone [MSH]
    • C07K14/685—Alpha-melanotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Pyrane Compounds (AREA)
  • Cosmetics (AREA)
DE69932424T 1998-05-05 1999-05-05 Melanocortin-1-rezeptor-selektive verbindungen Expired - Lifetime DE69932424T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9801571A SE9801571D0 (sv) 1998-05-05 1998-05-05 Melanokortin-1-receptorselektiva föreningar
SE9801571 1998-05-05
PCT/GB1999/001388 WO1999057148A1 (en) 1998-05-05 1999-05-05 Melanocortin 1 receptor selective compounds

Publications (2)

Publication Number Publication Date
DE69932424D1 true DE69932424D1 (de) 2006-08-31
DE69932424T2 DE69932424T2 (de) 2007-02-22

Family

ID=20411194

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69932424T Expired - Lifetime DE69932424T2 (de) 1998-05-05 1999-05-05 Melanocortin-1-rezeptor-selektive verbindungen

Country Status (14)

Country Link
US (2) US7008925B1 (de)
EP (2) EP1693382A3 (de)
JP (1) JP4584450B2 (de)
AT (1) ATE333468T1 (de)
AU (1) AU765120B2 (de)
CA (1) CA2327550A1 (de)
CY (1) CY1105654T1 (de)
DE (1) DE69932424T2 (de)
DK (1) DK1075492T3 (de)
ES (1) ES2268862T3 (de)
NZ (1) NZ507792A (de)
PT (1) PT1075492E (de)
SE (1) SE9801571D0 (de)
WO (1) WO1999057148A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002064091A2 (en) 2001-02-13 2002-08-22 Palatin Technologies, Inc. Melanocortin metallopeptides for treatment of sexual dysfunction
EP1950223A3 (de) 1998-03-09 2009-05-13 Zealand Pharma A/S Pharmakologisch aktive Peptidkonjugate mit verringerter enzymatischer Hydrolysetendenz
SE9801571D0 (sv) 1998-05-05 1998-05-05 Wapharm Ab Melanokortin-1-receptorselektiva föreningar
US7176279B2 (en) 2000-06-28 2007-02-13 Palatin Technologies, Inc. Cyclic peptide compositions and methods for treatment of sexual dysfunction
CA2415938A1 (en) * 2000-07-14 2002-01-24 Zycos Inc. Alpha-msh related compounds and methods of use
DE10106852A1 (de) * 2001-02-14 2002-09-05 T Luger Entzündungshemmende Verbindungen
US20080009019A1 (en) * 2001-06-13 2008-01-10 Smithkline Beecham Corporation High throughput method for screening candidate compounds for biological activity
FR2826581B1 (fr) * 2001-06-29 2005-10-07 Oreal Utilisation du tripeptide lys-pro-val (kpv) dans le traitement des melanomes
FR2826580B1 (fr) * 2001-06-29 2005-09-30 Oreal Utilisation du tripeptide lys-pro-val (kpv) pour favoriser le renouvellement epidermique et la micro-cicatrisation cutanee superficielle et/ou ameliorer l'aspect esthetique des plaies et cicatrices
CA2620228C (en) 2005-08-26 2014-12-09 Action Pharma A/S Therapeutically active .alpha.-msh analogues
WO2009033792A2 (en) * 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Gamma 1 msh alone or in combination with pentagastrin as a therapeutic agent
AU2009257631B2 (en) * 2008-06-09 2014-07-24 Palatin Technologies, Inc. Melanocortin receptor-specific peptides for treatment of sexual dysfunction
AR072072A1 (es) * 2008-06-09 2010-08-04 Palatin Technologies Inc Peptidos especificos del receptor de melanocortina para el tratamiento de la obesidad / 669
UY32690A (es) 2009-06-08 2011-01-31 Astrazeneca Ab Péptidos específicos para receptores de melanocortina
EP2440572B1 (de) 2009-06-08 2017-04-05 Palatin Technologies, Inc. Lactam-gebrückte melanocortinrezeptorspezifische peptide
MX2011013117A (es) 2009-06-08 2012-05-23 Palatin Technologies Inc Peptidos especificos del receptor de melanocortina.
CA2781405A1 (en) 2009-11-23 2011-05-26 Palatin Technologies, Inc. Melanocortin-1 receptor-specific linear peptides
WO2011063366A1 (en) 2009-11-23 2011-05-26 Palatin Technologies, Inc. Melanocortin-1 receptor-specific cyclic peptides
JP5715104B2 (ja) * 2012-09-27 2015-05-07 アブビー インコーポレイティド 治療的に活性なα−ＭＳＨアナログ
WO2014060606A1 (en) 2012-10-19 2014-04-24 Txp Pharma Gmbh Alpha- and gamma-msh analogues
EP3134105B8 (de) 2014-04-22 2020-12-30 TXP Pharma GmbH Peptidanaloga mit verzweigten aminosäuresonde(n)
US9939338B2 (en) 2015-02-19 2018-04-10 Stmicroelectronics S.R.L. Pressure sensing device with cavity and related methods
US10729669B2 (en) 2015-07-28 2020-08-04 University Of Iowa Research Foundation Compositions and methods for treating cancer
AU2017281940B2 (en) * 2016-06-24 2024-07-11 University Of Iowa Research Foundation Compositions and methods of treating melanoma
US11529335B2 (en) 2020-07-31 2022-12-20 University Of Iowa Research Foundation Compositions and methods for treating cancer

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4288627A (en) 1980-02-12 1981-09-08 Phillips Petroleum Company Oxidation of thiols employing cobalt molybdate/triethylamine catalyst
AU639570B2 (en) 1990-05-09 1993-07-29 Novozymes A/S A cellulase preparation comprising an endoglucanase enzyme
US5814603A (en) 1992-06-12 1998-09-29 Affymax Technologies N.V. Compounds with PTH activity
US5731408A (en) 1995-04-10 1998-03-24 Arizona Board Of Regents On Behalf Of The University Of Arizona Peptides having potent antagonist and agonist bioactivities at melanocortin receptors
EP1950223A3 (de) 1998-03-09 2009-05-13 Zealand Pharma A/S Pharmakologisch aktive Peptidkonjugate mit verringerter enzymatischer Hydrolysetendenz
SE9801571D0 (sv) 1998-05-05 1998-05-05 Wapharm Ab Melanokortin-1-receptorselektiva föreningar
EP1076066A1 (de) 1999-07-12 2001-02-14 Zealand Pharmaceuticals A/S Peptide zur Senkung des Blutglukosespiegels
GB9927346D0 (en) 1999-11-18 2000-01-12 Melacure Therapeutics Ab Method for analysis and design of entities of a chemical or biochemical nature
GB0012370D0 (en) 2000-05-22 2000-07-12 Quadrant Holdings Cambridge Peptoids
CA2620228C (en) 2005-08-26 2014-12-09 Action Pharma A/S Therapeutically active .alpha.-msh analogues

Also Published As

Publication number Publication date
EP1693382A2 (de) 2006-08-23
DE69932424T2 (de) 2007-02-22
JP2002513555A (ja) 2002-05-14
JP4584450B2 (ja) 2010-11-24
US7008925B1 (en) 2006-03-07
SE9801571D0 (sv) 1998-05-05
CY1105654T1 (el) 2010-12-22
EP1693382A3 (de) 2006-11-08
AU3722299A (en) 1999-11-23
EP1075492A1 (de) 2001-02-14
NZ507792A (en) 2003-10-31
PT1075492E (pt) 2006-11-30
AU765120B2 (en) 2003-09-11
CA2327550A1 (en) 1999-11-11
US7662782B2 (en) 2010-02-16
ES2268862T3 (es) 2007-03-16
WO1999057148A1 (en) 1999-11-11
ATE333468T1 (de) 2006-08-15
EP1075492B1 (de) 2006-07-19
US20070027086A1 (en) 2007-02-01
DK1075492T3 (da) 2006-12-04

Similar Documents

Publication Publication Date Title
DE69932424D1 (de) Melanocortin 1 rezeptorselektive verbindungen
BRPI0006823B8 (pt) composição farmacêutica estabilizada, preparação de injeção, e kit comercial
MY141641A (en) Compositions comprising viruses and methods for concentrating virus preparations
MY142065A (en) Arylalkylamines, process for preparing them and pharmaceutical compositions containing them
JP2002527052A5 (de)
HUP0000547A2 (hu) Cinkmentes inzulinkristályok pulmonáris kompozíciókhoz
DE69007429D1 (de) Isoindolonderivate, ihre Herstellung und diese enthaltende pharmazeutische Zusammensetzungen.
DK0498069T3 (da) Ny anvendelse af peptidderivat
LU90987I2 (fr) Copaxone et ses dérivés pharmaceutiquement acceptables
KR910011891A (ko) 펩티드 화합물, 이의 제조방법 및 이를 함유하는 약학적 조성물
ATE195953T1 (de) Peptide zur induktion von immunantwort durch zytotoxischen t lymphocyten gegen das virus von hepatitis c
KR900006363A (ko) 신규한 펩티다제 억제제
HUP0302962A2 (hu) Béta-karbolinszármazékok, ezeket a vegyületeket tartalmazó gyógyászati készítmények és a vegyületek alkalmazása
KR860004081A (ko) 폴리펩티드의 제조방법
HUP0104452A2 (hu) Triciklusos vegyületeket tartalmazó gyógyászati kompozíció
KR930007972A (ko) 환상 혈관활성 펩티드
TW427982B (en) Polysubstituted 3-acylamino-5-phenyl-1,4-benzodiazepin-2-one derivatives, process for their preparation and the pharmaceutical compositions containing them
KR970707108A (ko) 항염증제로 유용한, 복소환부를 갖는 디-t-부틸페놀 화합물(DI-TERT-BUTYLPHENOL COMPOUNDS WITH HETEROCYCLIC MOIETY, USEFUL AS ANTI-INFLAMMATORY AGENTS)
TR200200125T2 (tr) Yeni aminotiyazol türevleri, bunların hazırlanması ve bunları içeren farmasötik kompozisyonlar.
KR900701828A (ko) 펩티드 화합물
ES2191343T3 (es) Derivado de ribonucleoxido y su procedimiento de preparacion.
HU896606D0 (en) Process for the preparation of aminoacid derivatives inhibiting enzymes and pharmaceutical compositions thereof
CO5140099A1 (es) Ciertas caprolactamas sustituidas, composiciones farmaceuticas que las contienen, y su uso en el tratamiento de tumores
KR910000791A (ko) 뉴로키닌 a 길항제
ATE131191T1 (de) Verträgliche polymermischungen.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition