ATE333468T1 - Melanocortin 1 rezeptorselektive verbindungen - Google Patents
Melanocortin 1 rezeptorselektive verbindungenInfo
- Publication number
- ATE333468T1 ATE333468T1 AT99919433T AT99919433T ATE333468T1 AT E333468 T1 ATE333468 T1 AT E333468T1 AT 99919433 T AT99919433 T AT 99919433T AT 99919433 T AT99919433 T AT 99919433T AT E333468 T1 ATE333468 T1 AT E333468T1
- Authority
- AT
- Austria
- Prior art keywords
- aminoacid
- alkyl
- compound
- receptors
- polypeptide
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 102000008314 Type 1 Melanocortin Receptor Human genes 0.000 title abstract 3
- 108010021428 Type 1 Melanocortin Receptor Proteins 0.000 title abstract 3
- 235000001014 amino acid Nutrition 0.000 abstract 4
- 150000001413 amino acids Chemical class 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 108020004414 DNA Proteins 0.000 abstract 2
- 125000000524 functional group Chemical group 0.000 abstract 2
- 108020001507 fusion proteins Proteins 0.000 abstract 2
- 102000037865 fusion proteins Human genes 0.000 abstract 2
- 125000002887 hydroxy group Chemical class [H]O* 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102000053602 DNA Human genes 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 230000004968 inflammatory condition Effects 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/68—Melanocyte-stimulating hormone [MSH]
- C07K14/685—Alpha-melanotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Pyrane Compounds (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9801571A SE9801571D0 (sv) | 1998-05-05 | 1998-05-05 | Melanokortin-1-receptorselektiva föreningar |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE333468T1 true ATE333468T1 (de) | 2006-08-15 |
Family
ID=20411194
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99919433T ATE333468T1 (de) | 1998-05-05 | 1999-05-05 | Melanocortin 1 rezeptorselektive verbindungen |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US7008925B1 (de) |
| EP (2) | EP1075492B1 (de) |
| JP (1) | JP4584450B2 (de) |
| AT (1) | ATE333468T1 (de) |
| AU (1) | AU765120B2 (de) |
| CA (1) | CA2327550A1 (de) |
| CY (1) | CY1105654T1 (de) |
| DE (1) | DE69932424T2 (de) |
| DK (1) | DK1075492T3 (de) |
| ES (1) | ES2268862T3 (de) |
| NZ (1) | NZ507792A (de) |
| PT (1) | PT1075492E (de) |
| SE (1) | SE9801571D0 (de) |
| WO (1) | WO1999057148A1 (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002064091A2 (en) | 2001-02-13 | 2002-08-22 | Palatin Technologies, Inc. | Melanocortin metallopeptides for treatment of sexual dysfunction |
| JP4394279B2 (ja) * | 1998-03-09 | 2010-01-06 | ジーランド ファーマ アクティーゼルスカブ | 酵素加水分解に対する傾向が減少した薬理学的に活性なペプチド複合体 |
| SE9801571D0 (sv) | 1998-05-05 | 1998-05-05 | Wapharm Ab | Melanokortin-1-receptorselektiva föreningar |
| US7176279B2 (en) | 2000-06-28 | 2007-02-13 | Palatin Technologies, Inc. | Cyclic peptide compositions and methods for treatment of sexual dysfunction |
| US7169603B2 (en) * | 2000-07-14 | 2007-01-30 | Mgi Pharma Biologics, Inc. | α-MSH related compounds and methods of use |
| DE10106852A1 (de) * | 2001-02-14 | 2002-09-05 | T Luger | Entzündungshemmende Verbindungen |
| US20080009019A1 (en) * | 2001-06-13 | 2008-01-10 | Smithkline Beecham Corporation | High throughput method for screening candidate compounds for biological activity |
| FR2826580B1 (fr) * | 2001-06-29 | 2005-09-30 | Oreal | Utilisation du tripeptide lys-pro-val (kpv) pour favoriser le renouvellement epidermique et la micro-cicatrisation cutanee superficielle et/ou ameliorer l'aspect esthetique des plaies et cicatrices |
| FR2826581B1 (fr) * | 2001-06-29 | 2005-10-07 | Oreal | Utilisation du tripeptide lys-pro-val (kpv) dans le traitement des melanomes |
| US8466104B2 (en) | 2005-08-26 | 2013-06-18 | Abbvie Inc. | Therapeutically active alpha MSH analogues |
| CA2699100A1 (en) * | 2007-09-11 | 2009-04-02 | Dorian Bevec | Use of a peptide as a therapeutic agent |
| AR072072A1 (es) * | 2008-06-09 | 2010-08-04 | Palatin Technologies Inc | Peptidos especificos del receptor de melanocortina para el tratamiento de la obesidad / 669 |
| JP5628796B2 (ja) | 2008-06-09 | 2014-11-19 | パラティン テクノロジーズ, インコーポレイテッドPalatin Technologies, Inc. | 性的不能の治療用のメラノコルチンレセプタ特異的ペプチド |
| WO2010144344A2 (en) | 2009-06-08 | 2010-12-16 | Palatin Technologies, Inc. | Melanocortin receptor-specific peptides |
| UY32690A (es) * | 2009-06-08 | 2011-01-31 | Astrazeneca Ab | Péptidos específicos para receptores de melanocortina |
| WO2010144341A2 (en) | 2009-06-08 | 2010-12-16 | Palatin Technologies, Inc. | Lactam-bridged melanocortin receptor-specific peptides |
| EA201290295A1 (ru) | 2009-11-23 | 2013-01-30 | Палатин Текнолоджиз, Инк. | Специфичные к рецептору меланокортина-1 линейные пептиды |
| AU2010321738B2 (en) | 2009-11-23 | 2016-07-14 | Palatin Technologies, Inc. | Melanocortin-1 receptor-specific cyclic peptides |
| JP5715104B2 (ja) * | 2012-09-27 | 2015-05-07 | アブビー インコーポレイティド | 治療的に活性なα−ＭＳＨアナログ |
| CA2888277C (en) | 2012-10-19 | 2023-09-05 | Txp Pharma Gmbh | Alpha- and gamma-msh analogues |
| DK3134105T3 (da) | 2014-04-22 | 2021-02-22 | Txp Pharma Gmbh | Peptidanaloger med én eller flere forgrenede aminosyreprober |
| US9939338B2 (en) | 2015-02-19 | 2018-04-10 | Stmicroelectronics S.R.L. | Pressure sensing device with cavity and related methods |
| US10729669B2 (en) | 2015-07-28 | 2020-08-04 | University Of Iowa Research Foundation | Compositions and methods for treating cancer |
| AU2017281940C1 (en) | 2016-06-24 | 2024-11-07 | University Of Iowa Research Foundation | Compositions and methods of treating melanoma |
| US11590209B2 (en) | 2020-01-21 | 2023-02-28 | Palatin Technologies, Inc. | Use of bremelanotide in patients with controlled hypertension |
| US11529335B2 (en) | 2020-07-31 | 2022-12-20 | University Of Iowa Research Foundation | Compositions and methods for treating cancer |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4288627A (en) | 1980-02-12 | 1981-09-08 | Phillips Petroleum Company | Oxidation of thiols employing cobalt molybdate/triethylamine catalyst |
| AU639570B2 (en) | 1990-05-09 | 1993-07-29 | Novozymes A/S | A cellulase preparation comprising an endoglucanase enzyme |
| US5814603A (en) | 1992-06-12 | 1998-09-29 | Affymax Technologies N.V. | Compounds with PTH activity |
| US5731408A (en) | 1995-04-10 | 1998-03-24 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Peptides having potent antagonist and agonist bioactivities at melanocortin receptors |
| JP4394279B2 (ja) | 1998-03-09 | 2010-01-06 | ジーランド ファーマ アクティーゼルスカブ | 酵素加水分解に対する傾向が減少した薬理学的に活性なペプチド複合体 |
| SE9801571D0 (sv) | 1998-05-05 | 1998-05-05 | Wapharm Ab | Melanokortin-1-receptorselektiva föreningar |
| EP1076066A1 (de) | 1999-07-12 | 2001-02-14 | Zealand Pharmaceuticals A/S | Peptide zur Senkung des Blutglukosespiegels |
| GB9927346D0 (en) | 1999-11-18 | 2000-01-12 | Melacure Therapeutics Ab | Method for analysis and design of entities of a chemical or biochemical nature |
| GB0012370D0 (en) | 2000-05-22 | 2000-07-12 | Quadrant Holdings Cambridge | Peptoids |
| US8466104B2 (en) | 2005-08-26 | 2013-06-18 | Abbvie Inc. | Therapeutically active alpha MSH analogues |
-
1998
- 1998-05-05 SE SE9801571A patent/SE9801571D0/xx unknown
-
1999
- 1999-05-05 AU AU37222/99A patent/AU765120B2/en not_active Ceased
- 1999-05-05 PT PT99919433T patent/PT1075492E/pt unknown
- 1999-05-05 AT AT99919433T patent/ATE333468T1/de active
- 1999-05-05 CA CA002327550A patent/CA2327550A1/en not_active Abandoned
- 1999-05-05 EP EP99919433A patent/EP1075492B1/de not_active Expired - Lifetime
- 1999-05-05 JP JP2000547116A patent/JP4584450B2/ja not_active Expired - Fee Related
- 1999-05-05 EP EP05028298A patent/EP1693382A3/de not_active Withdrawn
- 1999-05-05 NZ NZ507792A patent/NZ507792A/en unknown
- 1999-05-05 WO PCT/GB1999/001388 patent/WO1999057148A1/en not_active Ceased
- 1999-05-05 DE DE69932424T patent/DE69932424T2/de not_active Expired - Lifetime
- 1999-05-05 ES ES99919433T patent/ES2268862T3/es not_active Expired - Lifetime
- 1999-05-05 US US09/674,733 patent/US7008925B1/en not_active Expired - Fee Related
- 1999-05-05 DK DK99919433T patent/DK1075492T3/da active
-
2005
- 2005-12-29 US US11/319,584 patent/US7662782B2/en not_active Expired - Fee Related
-
2006
- 2006-10-10 CY CY20061101449T patent/CY1105654T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ507792A (en) | 2003-10-31 |
| EP1693382A2 (de) | 2006-08-23 |
| AU765120B2 (en) | 2003-09-11 |
| US7662782B2 (en) | 2010-02-16 |
| AU3722299A (en) | 1999-11-23 |
| JP4584450B2 (ja) | 2010-11-24 |
| ES2268862T3 (es) | 2007-03-16 |
| DK1075492T3 (da) | 2006-12-04 |
| EP1075492A1 (de) | 2001-02-14 |
| WO1999057148A1 (en) | 1999-11-11 |
| DE69932424D1 (de) | 2006-08-31 |
| CA2327550A1 (en) | 1999-11-11 |
| US20070027086A1 (en) | 2007-02-01 |
| JP2002513555A (ja) | 2002-05-14 |
| DE69932424T2 (de) | 2007-02-22 |
| CY1105654T1 (el) | 2010-12-22 |
| EP1693382A3 (de) | 2006-11-08 |
| PT1075492E (pt) | 2006-11-30 |
| SE9801571D0 (sv) | 1998-05-05 |
| US7008925B1 (en) | 2006-03-07 |
| EP1075492B1 (de) | 2006-07-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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