ATE303437T1 - Rezeptor des ob-proteins und verwandte zusammensetzungen und verfahren - Google Patents
Rezeptor des ob-proteins und verwandte zusammensetzungen und verfahrenInfo
- Publication number
- ATE303437T1 ATE303437T1 AT97901343T AT97901343T ATE303437T1 AT E303437 T1 ATE303437 T1 AT E303437T1 AT 97901343 T AT97901343 T AT 97901343T AT 97901343 T AT97901343 T AT 97901343T AT E303437 T1 ATE303437 T1 AT E303437T1
- Authority
- AT
- Austria
- Prior art keywords
- protein
- methods
- receptor
- nucleic acids
- receptors
- Prior art date
Links
- 102000016267 Leptin Human genes 0.000 title abstract 6
- 108010092277 Leptin Proteins 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 102000005962 receptors Human genes 0.000 abstract 4
- 108020003175 receptors Proteins 0.000 abstract 4
- 102000005861 leptin receptors Human genes 0.000 abstract 3
- 108010019813 leptin receptors Proteins 0.000 abstract 3
- 102000039446 nucleic acids Human genes 0.000 abstract 3
- 108020004707 nucleic acids Proteins 0.000 abstract 3
- 150000007523 nucleic acids Chemical class 0.000 abstract 3
- 230000000692 anti-sense effect Effects 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Emergency Medicine (AREA)
- Biophysics (AREA)
- Child & Adolescent Psychology (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Endocrinology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58282596A | 1996-01-04 | 1996-01-04 | |
| US77441496A | 1996-12-31 | 1996-12-31 | |
| PCT/US1997/000128 WO1997025424A1 (en) | 1996-01-04 | 1997-01-02 | Ob protein receptor and related compositions and methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE303437T1 true ATE303437T1 (de) | 2005-09-15 |
Family
ID=27078678
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97901343T ATE303437T1 (de) | 1996-01-04 | 1997-01-02 | Rezeptor des ob-proteins und verwandte zusammensetzungen und verfahren |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0877803B1 (de) |
| JP (1) | JP2000502569A (de) |
| AT (1) | ATE303437T1 (de) |
| AU (1) | AU1526297A (de) |
| DE (1) | DE69734096T2 (de) |
| DK (1) | DK0877803T3 (de) |
| ES (1) | ES2244990T3 (de) |
| IL (1) | IL125081A (de) |
| NZ (1) | NZ534416A (de) |
| PT (1) | PT877803E (de) |
| WO (1) | WO1997025424A1 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6001968A (en) | 1994-08-17 | 1999-12-14 | The Rockefeller University | OB polypeptides, modified forms and compositions |
| US6977240B1 (en) | 1995-11-27 | 2005-12-20 | Millenium Pharmaceuticals, Inc. | Methods of using the OB receptor antibodies to treat bodyweight disorders |
| US6482927B1 (en) * | 1995-11-27 | 2002-11-19 | Millennium Pharmaceuticals, Inc. | Chimeric proteins comprising the extracellular domain of murine Ob receptor |
| US20050019325A1 (en) | 1996-01-08 | 2005-01-27 | Carter Paul J. | WSX receptor agonist antibodies |
| US7074397B1 (en) | 1996-01-08 | 2006-07-11 | Genentech, Inc. | Method for enhancing proliferation or differentiation of a cell using ob protein |
| US6541604B1 (en) | 1996-01-08 | 2003-04-01 | Genentech, Inc. | Leptin receptor having a WSX motif |
| AU2476301A (en) * | 1996-01-16 | 2001-05-24 | Rockefeller University, The | DB the receptor for leptin nucleic acids encoding the receptor, and uses thereof |
| US7084252B1 (en) | 1996-01-16 | 2006-08-01 | The Rockefeller University | DB, the receptor for leptin |
| US7148004B1 (en) | 1997-01-16 | 2006-12-12 | The Rockefeller University | Oligonucleotides of the OB-R isoforms and methods of diagnosing body weight |
| US7063958B1 (en) * | 1996-01-16 | 2006-06-20 | The Rockefeller University | Nucleic acids db, the receptor for leptin |
| US7619079B2 (en) | 1996-02-14 | 2009-11-17 | The Rockefeller University | Db, the receptor for leptin, nucleic acids encoding the receptor, and uses thereof |
| EP0921820A4 (de) * | 1996-06-20 | 2003-01-15 | Merck & Co Inc | Genterapie für die fettleibigkeit |
| WO1998057177A1 (en) * | 1997-06-09 | 1998-12-17 | Regeneron Pharmaceuticals, Inc. | Assay systems for leptin-enhancing agents |
| US20020192751A1 (en) | 1998-05-15 | 2002-12-19 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US6770444B2 (en) | 1998-07-16 | 2004-08-03 | Synaptic Pharmaceutical Corporation | Methods of identifying or screening for agents that binds the Ob-Re |
| FR2836475B1 (fr) * | 2002-02-26 | 2007-02-23 | Aventis Pharma Sa | Procede de detection de ligands du recepteur de la leptine |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5643748A (en) * | 1994-09-14 | 1997-07-01 | Progenitor, Inc. | HU-B1.219, a novel human hematopoietin receptor |
| US6482927B1 (en) * | 1995-11-27 | 2002-11-19 | Millennium Pharmaceuticals, Inc. | Chimeric proteins comprising the extracellular domain of murine Ob receptor |
| DE69734443T2 (de) * | 1996-01-08 | 2006-07-13 | Genentech, Inc., South San Francisco | Ob-rezeptor und liganden |
| US7063958B1 (en) * | 1996-01-16 | 2006-06-20 | The Rockefeller University | Nucleic acids db, the receptor for leptin |
| ATE320479T1 (de) * | 1996-01-23 | 2006-04-15 | Indevus Pharmaceuticals Inc | Process zur verwendung des obese-gens und seines genprodukts zur stimulierung der entwicklung von haemotopoietischen zellen |
-
1997
- 1997-01-02 DK DK97901343T patent/DK0877803T3/da active
- 1997-01-02 JP JP9525312A patent/JP2000502569A/ja not_active Ceased
- 1997-01-02 NZ NZ534416A patent/NZ534416A/en unknown
- 1997-01-02 ES ES97901343T patent/ES2244990T3/es not_active Expired - Lifetime
- 1997-01-02 EP EP97901343A patent/EP0877803B1/de not_active Expired - Lifetime
- 1997-01-02 PT PT97901343T patent/PT877803E/pt unknown
- 1997-01-02 AT AT97901343T patent/ATE303437T1/de not_active IP Right Cessation
- 1997-01-02 DE DE69734096T patent/DE69734096T2/de not_active Expired - Fee Related
- 1997-01-02 AU AU15262/97A patent/AU1526297A/en not_active Abandoned
- 1997-01-02 WO PCT/US1997/000128 patent/WO1997025424A1/en not_active Ceased
- 1997-01-02 IL IL125081A patent/IL125081A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69734096T2 (de) | 2006-06-29 |
| NZ534416A (en) | 2005-12-23 |
| IL125081A0 (en) | 1999-01-26 |
| ES2244990T3 (es) | 2005-12-16 |
| EP0877803B1 (de) | 2005-08-31 |
| PT877803E (pt) | 2005-11-30 |
| DE69734096D1 (de) | 2005-10-06 |
| AU1526297A (en) | 1997-08-01 |
| JP2000502569A (ja) | 2000-03-07 |
| DK0877803T3 (da) | 2005-09-19 |
| EP0877803A1 (de) | 1998-11-18 |
| IL125081A (en) | 2006-08-01 |
| WO1997025424A1 (en) | 1997-07-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0877803 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |