FI813198L - Foerfarande foer framstaellning av farmakologiskt aktiva peptider - Google Patents

Foerfarande foer framstaellning av farmakologiskt aktiva peptider

Info

Publication number
FI813198L
FI813198L FI813198A FI813198A FI813198L FI 813198 L FI813198 L FI 813198L FI 813198 A FI813198 A FI 813198A FI 813198 A FI813198 A FI 813198A FI 813198 L FI813198 L FI 813198L
Authority
FI
Finland
Prior art keywords
pharmacological
framework
product
activity
pharmacological activity
Prior art date
Application number
FI813198A
Other languages
English (en)
Inventor
Paul David Gesellchen
Robert Theodore Shuman
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of FI813198L publication Critical patent/FI813198L/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1027Tetrapeptides containing heteroatoms different from O, S, or N
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1016Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
FI813198A 1980-10-20 1981-10-14 Foerfarande foer framstaellning av farmakologiskt aktiva peptider FI813198L (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/198,900 US4322340A (en) 1980-10-20 1980-10-20 Pharmacologically active peptides

Publications (1)

Publication Number Publication Date
FI813198L true FI813198L (fi) 1982-04-21

Family

ID=22735344

Family Applications (1)

Application Number Title Priority Date Filing Date
FI813198A FI813198L (fi) 1980-10-20 1981-10-14 Foerfarande foer framstaellning av farmakologiskt aktiva peptider

Country Status (27)

Country Link
US (1) US4322340A (fi)
EP (1) EP0050502B1 (fi)
JP (1) JPS57108052A (fi)
KR (1) KR830007518A (fi)
AR (1) AR230046A1 (fi)
AT (1) ATE6777T1 (fi)
AU (1) AU547221B2 (fi)
BG (1) BG36928A3 (fi)
CA (1) CA1187871A (fi)
DD (1) DD200798A5 (fi)
DE (1) DE3162823D1 (fi)
DK (1) DK461481A (fi)
ES (1) ES8306713A1 (fi)
FI (1) FI813198L (fi)
GB (1) GB2085893B (fi)
GR (1) GR75342B (fi)
HU (1) HU185320B (fi)
IE (1) IE52186B1 (fi)
IL (1) IL64083A (fi)
NZ (1) NZ198628A (fi)
PH (1) PH17006A (fi)
PL (1) PL131155B1 (fi)
PT (1) PT73839B (fi)
RO (1) RO83301B (fi)
SU (1) SU1082319A3 (fi)
YU (1) YU249081A (fi)
ZA (1) ZA817063B (fi)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3267380D1 (en) * 1981-06-22 1985-12-19 Ici Plc Peptides and pseudopeptides in which the n terminus bears two substituents
US4448717A (en) * 1982-11-12 1984-05-15 Eli Lilly And Company Pharmacologically active peptides
US4473497A (en) * 1983-03-07 1984-09-25 Eli Lilly And Company Pharmacologically active peptides
DK134784A (da) * 1983-03-07 1984-09-08 Lilly Co Eli Farmakologisk virksomme tripeptid-derivater og fremgangsmaade til fremstilling deraf
US4510082A (en) * 1983-03-07 1985-04-09 Eli Lilly And Company Pharmacologically active peptides
US4495178A (en) * 1983-10-06 1985-01-22 G. D. Searle & Co. Enkephalin analogs
JPH0449298A (ja) * 1990-06-19 1992-02-18 Univ New York State 新規なエンケファリン誘導体および鎮痛剤
US5209930A (en) * 1990-12-10 1993-05-11 Rohm And Haas Company Preparation and use of n-iodopropargyl oxycarbonyl amino acid esters and derivatives as antimicrobial agents
US5952465A (en) * 1993-04-23 1999-09-14 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
US5928896A (en) * 1993-04-23 1999-07-27 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein--protein interaction site
US5965698A (en) * 1993-04-23 1999-10-12 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein--protein interaction site
US6258550B1 (en) 1993-04-23 2001-07-10 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
WO1994025482A1 (en) * 1993-04-23 1994-11-10 Evans Herbert J Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
US6084066A (en) * 1993-10-29 2000-07-04 Virginia Commonwealth University Polypetides that include conformation-constraining groups which flank a protein-protein interaction site

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1577115A (en) * 1976-07-27 1980-10-22 Reckitt & Colmann Prod Ltd Container closure units
FI770219A (fi) * 1976-02-02 1977-08-03 Sandoz Ag
CH619686A5 (en) * 1976-02-02 1980-10-15 Sandoz Ag Process for the preparation of novel peptides or peptide derivatives
US4264491A (en) * 1977-10-03 1981-04-28 Eli Lilly And Company Analgesic compounds
US4265808A (en) * 1979-12-17 1981-05-05 Eli Lilly And Company Pharmacologically active peptides

Also Published As

Publication number Publication date
HU185320B (en) 1985-01-28
DK461481A (da) 1982-04-21
US4322340A (en) 1982-03-30
ZA817063B (en) 1983-05-25
PT73839B (en) 1983-01-17
RO83301A (ro) 1984-02-21
AU547221B2 (en) 1985-10-10
EP0050502B1 (en) 1984-03-21
PL233498A1 (fi) 1982-05-24
KR830007518A (ko) 1983-10-21
NZ198628A (en) 1985-01-31
DD200798A5 (de) 1983-06-15
ATE6777T1 (de) 1984-04-15
DE3162823D1 (en) 1984-04-26
ES506316A0 (es) 1983-06-01
YU249081A (en) 1983-12-31
RO83301B (ro) 1984-02-28
PT73839A (en) 1981-11-01
IE52186B1 (en) 1987-08-05
JPS57108052A (en) 1982-07-05
GB2085893A (en) 1982-05-06
IL64083A (en) 1985-03-31
IE812442L (en) 1982-04-20
PH17006A (en) 1984-05-11
IL64083A0 (en) 1982-01-31
ES8306713A1 (es) 1983-06-01
AU7657481A (en) 1982-04-29
AR230046A1 (es) 1984-02-29
GR75342B (fi) 1984-07-13
PL131155B1 (en) 1984-10-31
SU1082319A3 (ru) 1984-03-23
EP0050502A1 (en) 1982-04-28
CA1187871A (en) 1985-05-28
BG36928A3 (en) 1985-02-15
GB2085893B (en) 1984-03-21

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: ELI LILLY AND COMPANY