KR830005849A - 수중에서 이버멕틴의 용매화 - Google Patents

수중에서 이버멕틴의 용매화 Download PDF

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Publication number
KR830005849A
KR830005849A KR1019810002670A KR810002670A KR830005849A KR 830005849 A KR830005849 A KR 830005849A KR 1019810002670 A KR1019810002670 A KR 1019810002670A KR 810002670 A KR810002670 A KR 810002670A KR 830005849 A KR830005849 A KR 830005849A
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KR
South Korea
Prior art keywords
water
ivermectin
solvation
desired capacity
parenteral
Prior art date
Application number
KR1019810002670A
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English (en)
Other versions
KR860001503B1 (ko
Inventor
알버트 로 팍-칸
비. 윌리암스 제임스
Original Assignee
제임스 에프, 너우톤
맬크 앤드 캄파니 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 제임스 에프, 너우톤, 맬크 앤드 캄파니 인코포레이티드 filed Critical 제임스 에프, 너우톤
Publication of KR830005849A publication Critical patent/KR830005849A/ko
Application granted granted Critical
Publication of KR860001503B1 publication Critical patent/KR860001503B1/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

내용 없음

Description

수중에서 이버멕틴의 용매화
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (1)

  1. 보문에 상술한 바와 같이, 비경구투여하기에 적합한 일종 이상의 물과 혼화가능한 유기 용매로 구성되는 공용매, 및 비경구 또는 경구 투여하기에 적합한 일종 이상의 기질중 하나 또는 모두를 함유하는 계면 활성제에 이버멕틴을 용해시키고, 이렇게 제조된 용액에 소기 용량까지 물을 가하여, 필요에 따라 pH를 조절하는 것으로 구성된, 이버멕틴을 함유하는 안정된 수성제재의 제조방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019810002670A 1980-08-04 1981-07-23 이버멕틴의 수용화 방법 KR860001503B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17495780A 1980-08-04 1980-08-04
US174957 1980-08-04
US174,957 1980-08-04

Publications (2)

Publication Number Publication Date
KR830005849A true KR830005849A (ko) 1983-09-14
KR860001503B1 KR860001503B1 (ko) 1986-09-30

Family

ID=22638223

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019810002670A KR860001503B1 (ko) 1980-08-04 1981-07-23 이버멕틴의 수용화 방법

Country Status (17)

Country Link
EP (1) EP0045655B1 (ko)
JP (1) JPS5765330A (ko)
KR (1) KR860001503B1 (ko)
AR (1) AR229354A1 (ko)
AT (1) ATE12179T1 (ko)
AU (1) AU551280B2 (ko)
CA (1) CA1162857A (ko)
DE (1) DE3169381D1 (ko)
DK (1) DK163637C (ko)
ES (1) ES8607721A1 (ko)
GR (1) GR74604B (ko)
IE (1) IE51460B1 (ko)
NZ (1) NZ197796A (ko)
OA (1) OA06863A (ko)
PT (1) PT73471B (ko)
YU (1) YU183181A (ko)
ZA (1) ZA815317B (ko)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4485099A (en) * 1983-06-15 1984-11-27 Merck & Co., Inc. Renin inhibitors containing a C-terminal amide cycle
US4477440A (en) * 1983-09-14 1984-10-16 Merck & Co., Inc. Renin inhibitors containing an n-terminal disulfide cycle
NZ210505A (en) * 1983-12-22 1988-06-30 Merck & Co Inc Parasiticidal compositions containing avermectin or milbemycin derivatives
IL89049A0 (en) * 1988-01-29 1989-08-15 Merrell Dow Pharma Pharmaceutical composition containing 4-aroylimidazol-2-ones
GB8803836D0 (en) * 1988-02-18 1988-03-16 Glaxo Group Ltd Compositions
JP2680614B2 (ja) * 1988-08-01 1997-11-19 日清製粉株式会社 ダナゾール組成物
NZ335166A (en) 1999-04-14 2001-11-30 Ashmont Holdings Ltd Anthelmintic composition containing triclabendazole in at least one solvent
US5419897A (en) * 1993-04-09 1995-05-30 Buckman Laboratories International, Inc. Ionene polymers as anthelmintics in animals
PL174488B1 (pl) * 1993-05-10 1998-08-31 Merck & Co Inc Preparat do zwalczania pasożytów zwierząt oraz sposób wytwarzania preparatu do zwalczania pasożytów zwierząt
WO1994026113A2 (en) * 1993-05-10 1994-11-24 Merck & Co., Inc. Pour-on formulations containinng polymeric material, glycols and glycerides
US5602107A (en) * 1993-05-10 1997-02-11 Merck & Co., Inc. Pour-on formulations consisting of gylcols, glycerides and avermectin compounds
JP2855181B2 (ja) 1993-12-10 1999-02-10 敏雄 鈴木 松類の枯損防止用組成物及び防止方法
DE19613972A1 (de) * 1996-04-09 1997-10-16 Bayer Ag Injektionsformulierungen von Avermectinen und Milbemycinen auf Basis von Rizinusöl
DE19638045A1 (de) * 1996-09-18 1998-03-19 Bayer Ag Injektionsformulierungen von Avermectinen und Milbemycinen
JP2002535268A (ja) * 1999-01-25 2002-10-22 オプティム セラピューティクス， インコーポレイテッド リポソーム処方物
US6780885B1 (en) * 2000-01-14 2004-08-24 Idexx Laboratories, Inc. Formulations and methods for administration of pharmacologically or biologically active compounds
RU2162699C1 (ru) * 2000-02-14 2001-02-10 Закрытое Акционерное Общество "Нита-Фарм" Водно-дисперсная лекарственная форма ивермектина для лечения экто- и эндопаразитозов
BG64140B1 (bg) * 2000-12-21 2004-02-27 "Биовет" Ад Състав за растителна защита с инсектицидно и акарицидно действие
GB2386066A (en) 2002-02-28 2003-09-10 Norbrook Lab Ltd Long-acting parasiticidal composition with improved bioavailability comprising a salicylanilide, a further anti-parasitic compound & a polymeric species
AU2002952597A0 (en) * 2002-11-11 2002-11-28 Schering-Plough Pty. Limited Topical parasiticide formulations and methods of treatment
DE10331253B4 (de) * 2003-01-28 2007-03-08 Alpha-Biocare Gmbh Therapeutika gegen Parasiten von Fischen
FR2854074B1 (fr) 2003-04-24 2007-11-23 Galderma Res & Dev Utilisation de l'ivermectine pour le traitement de desordres dermatologiques
GB0316377D0 (en) 2003-07-12 2003-08-13 Norbrook Lab Ltd Parasiticidal composition
WO2006069580A1 (en) * 2004-12-30 2006-07-06 Cheminova A/S Oil-in-water formulation of avermectins
FR2894823B1 (fr) 2005-12-20 2008-02-29 Galderma Sa Composition de type emulsion inverse comprenant de l'ivermectine, et ses utilisations en cosmetique et en dermatologie
CA2737102C (en) 2008-10-08 2014-02-18 Wyeth Llc Benzimidazole anthelmintic compositions
BRPI0804639A2 (pt) * 2008-10-23 2010-07-20 Formil Veterinaria Ltda processo para preparação de formulação de suspensão veterinária para administração de medicamento insolúvel em água, por meio de sistemas de distribuição de água e respectiva formulação de suspensão veterinária para administração de medicamento insolúvel em água
ES2719200T3 (es) 2008-10-29 2019-07-09 Arbor Pharmaceuticals Llc Sistema conservante para formulaciones tópicas terapéuticas basadas en emulsión
JP5717034B2 (ja) * 2012-08-27 2015-05-13 丸和バイオケミカル株式会社 マクロライド系化合物を含有する土壌線虫防除用薬剤
KR20150125639A (ko) 2013-03-06 2015-11-09 세키스이가가쿠 고교가부시키가이샤 수지 복합 재료의 제조 방법 및 수지 복합 재료
US9233118B2 (en) 2013-07-08 2016-01-12 Galderma S.A. Treatment of papulopustular rosacea with ivermectin
FR3042412A1 (fr) * 2015-10-14 2017-04-21 Biotopic Pharmaceuticals Formulation pharmaceutique stabilisee et prete a l'emploi d'ivermectine dans le traitement des parasitoses humaines et animales
CN107802599A (zh) * 2017-12-08 2018-03-16 宁夏大学 一种驼用饮水型驱虫溶液的研制和使用方法
PT110634B (pt) 2018-03-19 2021-03-17 Hovione Farmaciencia Sa Ivermectina amorfa e processo para a sua produção
CN109966438A (zh) * 2019-05-17 2019-07-05 石家庄九鼎动物药业有限公司 一种兽用抗寄生虫药物伊维菌素注射液及其制备方法
US11638714B2 (en) 2020-11-10 2023-05-02 Mountain Valley Md Inc Water dissolvable macrocyclic lactone cyclodextrin complexes
US11077134B1 (en) 2020-11-10 2021-08-03 Mountain Valley Md Inc Water dissolvable macrocyclic lactone cyclodextrin complexes

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB784659A (en) * 1954-11-26 1957-10-16 Upjohn Co Therapeutic compositions and aqueous suspensions thereof
CH420490A (de) * 1961-10-16 1966-09-15 Hoffmann La Roche Wässriges Verdünnungsmittel zur Herstellung von parenteralen Injektionslösungen und Verfahren zu dessen Herstellung
GB1225979A (ko) * 1967-03-23 1971-03-24
US4199569A (en) * 1977-10-03 1980-04-22 Merck & Co., Inc. Selective hydrogenation products of C-076 compounds and derivatives thereof

Also Published As

Publication number Publication date
YU183181A (en) 1984-02-29
ATE12179T1 (de) 1985-04-15
AU551280B2 (en) 1986-04-24
OA06863A (fr) 1983-02-28
AR229354A1 (es) 1983-07-29
DK345081A (da) 1982-02-05
PT73471A (en) 1981-09-01
JPH057371B2 (ko) 1993-01-28
ES8607721A1 (es) 1986-06-01
IE811751L (en) 1982-02-04
EP0045655B1 (en) 1985-03-20
DK163637B (da) 1992-03-23
IE51460B1 (en) 1986-12-24
NZ197796A (en) 1984-11-09
JPS5765330A (en) 1982-04-20
GR74604B (ko) 1984-06-29
ES504513A0 (es) 1986-06-01
DE3169381D1 (en) 1985-04-25
CA1162857A (en) 1984-02-28
EP0045655A3 (en) 1982-10-06
KR860001503B1 (ko) 1986-09-30
PT73471B (en) 1983-07-06
AU7361281A (en) 1982-02-11
EP0045655A2 (en) 1982-02-10
ZA815317B (en) 1983-03-30
DK163637C (da) 1992-08-17

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