DK345081A - Fremgangsmaade til fremstilling af et stabilt vandigt praeparat indeholdende invermectin - Google Patents

Fremgangsmaade til fremstilling af et stabilt vandigt praeparat indeholdende invermectin

Info

Publication number
DK345081A
DK345081A DK345081A DK345081A DK345081A DK 345081 A DK345081 A DK 345081A DK 345081 A DK345081 A DK 345081A DK 345081 A DK345081 A DK 345081A DK 345081 A DK345081 A DK 345081A
Authority
DK
Denmark
Prior art keywords
invermectin
preparing
procedure
preparation containing
stable aqueous
Prior art date
Application number
DK345081A
Other languages
English (en)
Other versions
DK163637C (da
DK163637B (da
Inventor
P K A Lo
J B Williams
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK345081A publication Critical patent/DK345081A/da
Publication of DK163637B publication Critical patent/DK163637B/da
Application granted granted Critical
Publication of DK163637C publication Critical patent/DK163637C/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK345081A 1980-08-04 1981-08-03 Fremgangsmaade til fremstilling af et stabilt, vandigt praeparat indeholdende ivermectin DK163637C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17495780A 1980-08-04 1980-08-04
US17495780 1980-08-04

Publications (3)

Publication Number Publication Date
DK345081A true DK345081A (da) 1982-02-05
DK163637B DK163637B (da) 1992-03-23
DK163637C DK163637C (da) 1992-08-17

Family

ID=22638223

Family Applications (1)

Application Number Title Priority Date Filing Date
DK345081A DK163637C (da) 1980-08-04 1981-08-03 Fremgangsmaade til fremstilling af et stabilt, vandigt praeparat indeholdende ivermectin

Country Status (17)

Country Link
EP (1) EP0045655B1 (da)
JP (1) JPS5765330A (da)
KR (1) KR860001503B1 (da)
AR (1) AR229354A1 (da)
AT (1) ATE12179T1 (da)
AU (1) AU551280B2 (da)
CA (1) CA1162857A (da)
DE (1) DE3169381D1 (da)
DK (1) DK163637C (da)
ES (1) ES8607721A1 (da)
GR (1) GR74604B (da)
IE (1) IE51460B1 (da)
NZ (1) NZ197796A (da)
OA (1) OA06863A (da)
PT (1) PT73471B (da)
YU (1) YU183181A (da)
ZA (1) ZA815317B (da)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4485099A (en) * 1983-06-15 1984-11-27 Merck & Co., Inc. Renin inhibitors containing a C-terminal amide cycle
US4477440A (en) * 1983-09-14 1984-10-16 Merck & Co., Inc. Renin inhibitors containing an n-terminal disulfide cycle
NZ210505A (en) * 1983-12-22 1988-06-30 Merck & Co Inc Parasiticidal compositions containing avermectin or milbemycin derivatives
IL89049A0 (en) * 1988-01-29 1989-08-15 Merrell Dow Pharma Pharmaceutical composition containing 4-aroylimidazol-2-ones
GB8803836D0 (en) * 1988-02-18 1988-03-16 Glaxo Group Ltd Compositions
JP2680614B2 (ja) * 1988-08-01 1997-11-19 日清製粉株式会社 ダナゾール組成物
NZ335166A (en) 1999-04-14 2001-11-30 Ashmont Holdings Ltd Anthelmintic composition containing triclabendazole in at least one solvent
US5419897A (en) * 1993-04-09 1995-05-30 Buckman Laboratories International, Inc. Ionene polymers as anthelmintics in animals
PL173487B1 (pl) * 1993-05-10 1998-03-31 Merck & Co Inc Preparat do zwalczania wewnętrznych i zewnętrznych pasożytów zwierząt, sposób wytwarzania preparatu do zwalczania wewnętrznych i zewnętrznych pasożytów zwierząt oraz sposób zwalczania zewnętrznych pasożytów zwierząt
PL174488B1 (pl) * 1993-05-10 1998-08-31 Merck & Co Inc Preparat do zwalczania pasożytów zwierząt oraz sposób wytwarzania preparatu do zwalczania pasożytów zwierząt
US5602107A (en) * 1993-05-10 1997-02-11 Merck & Co., Inc. Pour-on formulations consisting of gylcols, glycerides and avermectin compounds
JP2855181B2 (ja) 1993-12-10 1999-02-10 敏雄 鈴木 松類の枯損防止用組成物及び防止方法
DE19613972A1 (de) * 1996-04-09 1997-10-16 Bayer Ag Injektionsformulierungen von Avermectinen und Milbemycinen auf Basis von Rizinusöl
DE19638045A1 (de) * 1996-09-18 1998-03-19 Bayer Ag Injektionsformulierungen von Avermectinen und Milbemycinen
JP2002535268A (ja) * 1999-01-25 2002-10-22 オプティム セラピューティクス, インコーポレイテッド リポソーム処方物
US6780885B1 (en) 2000-01-14 2004-08-24 Idexx Laboratories, Inc. Formulations and methods for administration of pharmacologically or biologically active compounds
RU2162699C1 (ru) * 2000-02-14 2001-02-10 Закрытое Акционерное Общество "Нита-Фарм" Водно-дисперсная лекарственная форма ивермектина для лечения экто- и эндопаразитозов
BG64140B1 (bg) * 2000-12-21 2004-02-27 "Биовет" Ад Състав за растителна защита с инсектицидно и акарицидно действие
GB2386066A (en) 2002-02-28 2003-09-10 Norbrook Lab Ltd Long-acting parasiticidal composition with improved bioavailability comprising a salicylanilide, a further anti-parasitic compound & a polymeric species
AU2002952597A0 (en) * 2002-11-11 2002-11-28 Schering-Plough Pty. Limited Topical parasiticide formulations and methods of treatment
DE10331253B4 (de) * 2003-01-28 2007-03-08 Alpha-Biocare Gmbh Therapeutika gegen Parasiten von Fischen
FR2854074B1 (fr) 2003-04-24 2007-11-23 Galderma Res & Dev Utilisation de l'ivermectine pour le traitement de desordres dermatologiques
GB0316377D0 (en) 2003-07-12 2003-08-13 Norbrook Lab Ltd Parasiticidal composition
WO2006069580A1 (en) * 2004-12-30 2006-07-06 Cheminova A/S Oil-in-water formulation of avermectins
FR2894823B1 (fr) 2005-12-20 2008-02-29 Galderma Sa Composition de type emulsion inverse comprenant de l'ivermectine, et ses utilisations en cosmetique et en dermatologie
WO2010042395A1 (en) 2008-10-08 2010-04-15 Wyeth Llc Benzimidazole anthelmintic compositions
BRPI0804639A2 (pt) * 2008-10-23 2010-07-20 Formil Veterinaria Ltda processo para preparação de formulação de suspensão veterinária para administração de medicamento insolúvel em água, por meio de sistemas de distribuição de água e respectiva formulação de suspensão veterinária para administração de medicamento insolúvel em água
WO2010051348A1 (en) 2008-10-29 2010-05-06 Topaz Pharmaceuticals Inc. Preservative system for emulsion-based therapeutic topical formulations
JP5717034B2 (ja) * 2012-08-27 2015-05-13 丸和バイオケミカル株式会社 マクロライド系化合物を含有する土壌線虫防除用薬剤
CN104884508A (zh) 2013-03-06 2015-09-02 积水化学工业株式会社 树脂复合材料的制造方法及树脂复合材料
US9233118B2 (en) 2013-07-08 2016-01-12 Galderma S.A. Treatment of papulopustular rosacea with ivermectin
FR3042412A1 (fr) * 2015-10-14 2017-04-21 Biotopic Pharmaceuticals Formulation pharmaceutique stabilisee et prete a l'emploi d'ivermectine dans le traitement des parasitoses humaines et animales
CN107802599A (zh) * 2017-12-08 2018-03-16 宁夏大学 一种驼用饮水型驱虫溶液的研制和使用方法
PT110634B (pt) 2018-03-19 2021-03-17 Hovione Farmaciencia Sa Ivermectina amorfa e processo para a sua produção
CN109966438A (zh) * 2019-05-17 2019-07-05 石家庄九鼎动物药业有限公司 一种兽用抗寄生虫药物伊维菌素注射液及其制备方法
US11077134B1 (en) 2020-11-10 2021-08-03 Mountain Valley Md Inc Water dissolvable macrocyclic lactone cyclodextrin complexes
US11638714B2 (en) 2020-11-10 2023-05-02 Mountain Valley Md Inc Water dissolvable macrocyclic lactone cyclodextrin complexes

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB784659A (en) * 1954-11-26 1957-10-16 Upjohn Co Therapeutic compositions and aqueous suspensions thereof
CH420490A (de) * 1961-10-16 1966-09-15 Hoffmann La Roche Wässriges Verdünnungsmittel zur Herstellung von parenteralen Injektionslösungen und Verfahren zu dessen Herstellung
GB1225979A (da) * 1967-03-23 1971-03-24
US4199569A (en) * 1977-10-03 1980-04-22 Merck & Co., Inc. Selective hydrogenation products of C-076 compounds and derivatives thereof

Also Published As

Publication number Publication date
AU551280B2 (en) 1986-04-24
ZA815317B (en) 1983-03-30
JPS5765330A (en) 1982-04-20
DK163637C (da) 1992-08-17
EP0045655A2 (en) 1982-02-10
EP0045655A3 (en) 1982-10-06
IE811751L (en) 1982-02-04
CA1162857A (en) 1984-02-28
ATE12179T1 (de) 1985-04-15
YU183181A (en) 1984-02-29
OA06863A (fr) 1983-02-28
AU7361281A (en) 1982-02-11
PT73471B (en) 1983-07-06
JPH057371B2 (da) 1993-01-28
KR830005849A (ko) 1983-09-14
NZ197796A (en) 1984-11-09
IE51460B1 (en) 1986-12-24
DE3169381D1 (en) 1985-04-25
ES504513A0 (es) 1986-06-01
KR860001503B1 (ko) 1986-09-30
DK163637B (da) 1992-03-23
AR229354A1 (es) 1983-07-29
PT73471A (en) 1981-09-01
ES8607721A1 (es) 1986-06-01
GR74604B (da) 1984-06-29
EP0045655B1 (en) 1985-03-20

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