KR830002800A - 서당 유도체 - Google Patents

서당 유도체 Download PDF

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Publication number
KR830002800A
KR830002800A KR1019800002441A KR800002441A KR830002800A KR 830002800 A KR830002800 A KR 830002800A KR 1019800002441 A KR1019800002441 A KR 1019800002441A KR 800002441 A KR800002441 A KR 800002441A KR 830002800 A KR830002800 A KR 830002800A
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South Korea
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group
formula
structural formula
compound
hydrogen
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KR1019800002441A
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English (en)
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KR840000678B1 (ko
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볼라크 베르너
삐에르-챨스위
Original Assignee
쿠르트 네겔보쉬·한스 스튀클린
에프. 호프만-라 롯슈 앤드 캄파니 아크티엔 게젤샤프트
한스 스튀클린
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Application filed by 쿠르트 네겔보쉬·한스 스튀클린, 에프. 호프만-라 롯슈 앤드 캄파니 아크티엔 게젤샤프트, 한스 스튀클린 filed Critical 쿠르트 네겔보쉬·한스 스튀클린
Publication of KR830002800A publication Critical patent/KR830002800A/ko
Priority to KR1019840001868A priority Critical patent/KR840000850B1/ko
Application granted granted Critical
Publication of KR840000678B1 publication Critical patent/KR840000678B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/38—Alcohols containing six-membered aromatic rings and other rings and having unsaturation outside the aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/782—Ketones containing a keto group bound to a six-membered aromatic ring polycyclic
    • C07C49/792—Ketones containing a keto group bound to a six-membered aromatic ring polycyclic containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/33—Polycyclic acids
    • C07C63/49—Polycyclic acids containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

내용 없음

Description

서당 유도체
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (16)

  1. 다음 구조식(II) 또는 (II-1)의 화합물을 수결합제 또는 산결합제 존재하에 구조식 R6OH(여기서 R6는 전술한 바와 같다)의 산 또는 이의 반응성 유도체와 반응시키거나, 다음 구조식(III)의 화합물을 탈아세틸화시키거나, 다음 구조식(IV)의 화합물을 메탄올성 암모니아와 반응시키고, 필요한 경우 수득된, R1이 저급 알콕시카보닐인 구조식(I)의 화합물을 R1이 카복실인 구조식(I)의 화합물 또는 이 화합물의 염으로전환시킴을 특징으로 하여 다음 구조식(I)의 화합물을 제조하는 방법.
  3. 상기 구조식에서
  4. R1은 구조식 -CH2OH, -CH2OR6, -COR7또는 -CONH2그룹이고
  5. R2는 수소 또는 저급 알카노일이고
  6. R3및 R4는 수소 또는 저급알카노일 또는 R6그룹이고
  7. R5는 저급알콕시 또는 구조식 OR6또는 OR8그룹이고
  8. R6는 다음 구조식의 그룹이고
  10. R7은 하이드록시, 저급알콕시 또는 OM(여기서 M은 양이온임)이고
  11. R8은 다음 구조식의 그룹이며
  13. (단, R5가 저급알콕시일 경우, R1은 구조식 -CH2OR6그룹이고 R2는 수소이며 R3및 R4중 하나가 수소이고 다른 하나는 R6그룹이고 R5가 구조식 OR6그룹일 경우, R1은 구조식 -COR7그룹이고 R2,R3및 R4는 저급알카노일이며 R5가 구조식 OR8그룹일 경우, R1은 구조식 -CH2OH, -COR7또는 -CONH2그룹이고 R2,R3및 R4는 수소 또는 저급 알카노일이다)
  14. R51은 저급알콕시이고
  15. Ac는 아세틸이다.
  16. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019800002441A 1979-06-21 1980-06-20 당유도체의 제조방법 KR840000678B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019840001868A KR840000850B1 (ko) 1979-06-21 1984-04-09 당 유도체의 제조방법

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH580879 1979-06-21
CH5808 1979-06-21

Publications (2)

Publication Number Publication Date
KR830002800A true KR830002800A (ko) 1983-05-30
KR840000678B1 KR840000678B1 (ko) 1984-05-18

Family

ID=4299652

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1019800002441A KR840000678B1 (ko) 1979-06-21 1980-06-20 당유도체의 제조방법
KR1019840001868A KR840000850B1 (ko) 1979-06-21 1984-04-09 당 유도체의 제조방법

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1019840001868A KR840000850B1 (ko) 1979-06-21 1984-04-09 당 유도체의 제조방법

Country Status (22)

Country Link
US (1) US4316983A (ko)
EP (1) EP0021339B1 (ko)
JP (1) JPS567798A (ko)
KR (2) KR840000678B1 (ko)
AR (2) AR225312A1 (ko)
AT (1) ATE2434T1 (ko)
AU (1) AU530478B2 (ko)
CA (1) CA1134819A (ko)
DE (1) DE3061891D1 (ko)
DK (1) DK154650C (ko)
ES (2) ES8104322A1 (ko)
FI (1) FI67386C (ko)
GR (1) GR69283B (ko)
HU (1) HU184915B (ko)
IE (1) IE50463B1 (ko)
IL (1) IL60324A (ko)
MC (1) MC1338A1 (ko)
NO (1) NO148644C (ko)
NZ (1) NZ194061A (ko)
PH (1) PH16243A (ko)
PT (1) PT71435B (ko)
ZA (1) ZA803538B (ko)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4987223A (en) * 1981-12-23 1991-01-22 Choay S.A. Derivatives of the uronic acid
US4388457A (en) * 1982-02-11 1983-06-14 University Patents, Inc. Phyllanthostatin compounds
CH661516A5 (de) * 1983-12-08 1987-07-31 Hoffmann La Roche Phenylnonatetraenoylzuckerderivate.
AU582758B2 (en) * 1984-06-28 1989-04-13 Mect Corporation Sialic acid derivatives, galactose derivatives and method for producing the same
CH667868A5 (fr) * 1984-09-05 1988-11-15 Oreal Derives du benzonorbornene, leurs procedes de preparation et compositions medicamenteuse et cosmetique les contenant.
LU85726A1 (fr) * 1985-01-10 1986-08-04 Cird Nouveaux derives naphtaleniques du benzonorbornene,leur procede de preparation et compositions medicamenteuse et cosmetique les contenant
EP0249008B1 (de) * 1986-05-09 1993-09-15 Pulverer, Gerhard, Prof. Dr.Dr.h.c. Verwendung von spezifischen Monosacchariden zur Herstellung eines Arzneimittels zur Verhinderung von Metastasen maligner Tumore
JPH03502327A (ja) * 1988-01-19 1991-05-30 ボード・オブ・リージェンツ，ザ・ユニバーシティ・オブ・テキサス・システム ３’‐デアミノドキソルビシンのエステル体、そのリポソーム組成物およびその使用方法
SE462229B (sv) * 1988-01-19 1990-05-21 Exma Extern Marknadsfoering Ab Laasanordning foer ett roerligt organ som aer svaengbart i foerhaallande till ett annat organ
US4943563A (en) * 1988-10-03 1990-07-24 Cornell Research Foundation, Inc. 2,3,4-triacylhexose insect repellants
DE3929355A1 (de) * 1989-09-04 1991-03-07 Boehringer Mannheim Gmbh Verfahren zur spezifischen bestimmung von pankreas-(alpha)-amylase
JP2674843B2 (ja) * 1989-10-31 1997-11-12 新日本製鐵株式会社 鋳鉄用被覆アーク溶接棒
US5523398A (en) * 1994-08-31 1996-06-04 The Center For Innovative Technology Cellulose derivatives with a low degree of substitution

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3629238A (en) * 1968-09-20 1971-12-21 Sumitomo Chemical Co Novel glucuronides of 3-indolylaliphatic acid derivatives
FR2141532B1 (ko) * 1971-06-14 1974-08-23 Anvar
FR2307820A1 (fr) * 1975-04-17 1976-11-12 Hayashibara Seibutsu Chem Inst Glycosides d'echinatine et leur preparation
JPS51125362A (en) * 1975-04-17 1976-11-01 Hayashibara Biochem Lab Inc Process for synthesizing echinatin glycosides
LU77254A1 (ko) * 1977-05-04 1979-01-18
DK159967C (da) * 1977-12-22 1991-06-03 Hoffmann La Roche Analogifremgangsmaade til fremstilling af terapeutisk aktive stilbenderivater

Also Published As

Publication number Publication date
PT71435B (en) 1981-10-22
DK154650B (da) 1988-12-05
ES492616A0 (es) 1981-04-16
DK262480A (da) 1980-12-22
ES8201175A1 (es) 1981-12-01
GR69283B (ko) 1982-05-13
NO148644B (no) 1983-08-08
IL60324A0 (en) 1980-09-16
ES8104322A1 (es) 1981-04-16
MC1338A1 (fr) 1981-04-21
AU530478B2 (en) 1983-07-14
DK154650C (da) 1989-05-01
FI801472A (fi) 1980-12-22
NO148644C (no) 1983-11-16
IE801280L (en) 1980-12-21
AR225312A1 (es) 1982-03-15
FI67386B (fi) 1984-11-30
ES498607A0 (es) 1981-12-01
PH16243A (en) 1983-08-11
NO801862L (no) 1980-12-22
IL60324A (en) 1984-01-31
KR840000678B1 (ko) 1984-05-18
PT71435A (en) 1980-07-01
US4316983A (en) 1982-02-23
DE3061891D1 (en) 1983-03-17
AR229247A1 (es) 1983-07-15
HU184915B (en) 1984-11-28
AU5902980A (en) 1981-01-08
KR840000850B1 (ko) 1984-06-19
JPH0131518B2 (ko) 1989-06-26
CA1134819A (en) 1982-11-02
ATE2434T1 (de) 1983-03-15
IE50463B1 (en) 1986-04-30
JPS567798A (en) 1981-01-27
FI67386C (fi) 1985-03-11
ZA803538B (en) 1981-06-24
NZ194061A (en) 1982-09-07
EP0021339B1 (de) 1983-02-09
EP0021339A1 (de) 1981-01-07

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