KR20240045351A - 연골 손상 및 관절염 치료 방법 및 조성물 - Google Patents

연골 손상 및 관절염 치료 방법 및 조성물 Download PDF

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Publication number
KR20240045351A
KR20240045351A KR1020247009753A KR20247009753A KR20240045351A KR 20240045351 A KR20240045351 A KR 20240045351A KR 1020247009753 A KR1020247009753 A KR 1020247009753A KR 20247009753 A KR20247009753 A KR 20247009753A KR 20240045351 A KR20240045351 A KR 20240045351A
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KR
South Korea
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Pending
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KR1020247009753A
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English (en)
Korean (ko)
Inventor
크리스틴 존슨
요르크 골트한
첼레스테 슈코티
이고어 포스티아어
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노파르티스 아게
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Publication of KR20240045351A publication Critical patent/KR20240045351A/ko
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Biomedical Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020247009753A 2016-11-14 2017-11-13 연골 손상 및 관절염 치료 방법 및 조성물 Pending KR20240045351A (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201662421534P 2016-11-14 2016-11-14
US62/421,534 2016-11-14
US201762560301P 2017-09-19 2017-09-19
US62/560,301 2017-09-19
PCT/IB2017/057081 WO2018087727A1 (en) 2016-11-14 2017-11-13 Methods and compositions for treatment of cartilage damage and arthritis
KR1020197016715A KR20190084287A (ko) 2016-11-14 2017-11-13 연골 손상 및 관절염 치료 방법 및 조성물

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020197016715A Division KR20190084287A (ko) 2016-11-14 2017-11-13 연골 손상 및 관절염 치료 방법 및 조성물

Publications (1)

Publication Number Publication Date
KR20240045351A true KR20240045351A (ko) 2024-04-05

Family

ID=60629753

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020247009753A Pending KR20240045351A (ko) 2016-11-14 2017-11-13 연골 손상 및 관절염 치료 방법 및 조성물
KR1020197016715A Ceased KR20190084287A (ko) 2016-11-14 2017-11-13 연골 손상 및 관절염 치료 방법 및 조성물

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020197016715A Ceased KR20190084287A (ko) 2016-11-14 2017-11-13 연골 손상 및 관절염 치료 방법 및 조성물

Country Status (10)

Country Link
US (3) US11351223B2 (https=)
EP (1) EP3538127A1 (https=)
JP (2) JP2019535707A (https=)
KR (2) KR20240045351A (https=)
CN (2) CN109963579A (https=)
AU (2) AU2017357785A1 (https=)
CA (1) CA3043667A1 (https=)
IL (1) IL266361B2 (https=)
MX (2) MX2019005621A (https=)
WO (1) WO2018087727A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024519893A (ja) 2021-05-24 2024-05-21 ノバルティス アーゲー 変形性関節症の治療方法
TW202306970A (zh) 2021-05-24 2023-02-16 瑞士商諾華公司 用於治療骨關節炎之方法
CN118251594A (zh) * 2021-11-10 2024-06-25 诺华股份有限公司 用于确定angptl多肽的生物活性的方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002085923A2 (en) 2001-04-19 2002-10-31 The Scripps Research Institute In vivo incorporation of unnatural amino acids
MXPA05003978A (es) 2002-10-16 2005-06-22 Scripps Research Inst Sintesis de glicoproteinas.
JP4444113B2 (ja) 2002-10-16 2010-03-31 ザ スクリップス リサーチ インスティテュート ケトアミノ酸の部位特異的蛋白質組込み方法
JP5642916B2 (ja) 2003-04-17 2014-12-17 ザ スクリプス リサーチ インスティテュート 真核遺伝コードの拡張
US20060160175A1 (en) 2003-07-07 2006-07-20 The Scripps Research Institute Compositions of orthogonal leucyl-trna and aminoacyl-trna synthetase pairs and uses thereof
WO2005007624A2 (en) 2003-07-07 2005-01-27 The Scripps Research Institute Compositions of orthogonal glutamyl-trna and aminoacyl trna synthetase pairs and uses thereof
EP1649004A4 (en) 2003-07-07 2008-04-09 Scripps Research Inst COMPOSITIONS WITH PAIRS OF ORTHOGONAL LYSYL-TRNA AND AMINOACYL-TRNA-SYNTHETASE AND USES THEREOF
AU2005286722B2 (en) 2004-09-21 2010-12-02 The Scripps Research Institute In vivo incorporation of alkynyl amino acids into proteins in eubacteria
CN101048506B (zh) 2004-10-27 2013-06-26 斯克利普斯研究院 体内掺入非天然氨基酸的正交翻译组分
KR20080106430A (ko) 2006-03-09 2008-12-05 더 스크립스 리서치 인스티튜트 진정 세균 숙주 세포 내에서의 직교형 번역 성분의 발현을 위한 시스템
US8575397B2 (en) 2007-02-14 2013-11-05 Biocompatibles Uk Limited Derivatisation of biological molecules
AU2009324354B2 (en) * 2008-12-10 2016-04-14 Ablynx Nv Amino acid sequences directed against the Angiopoietin/Tie system and polypeptides comprising the same for the treatment of diseases and disorders related to angiogenesis
JP5602850B2 (ja) * 2009-07-14 2014-10-08 ザ スクリプス リサーチ インスティテュート 間葉幹細胞分化
UY32979A (es) * 2009-10-28 2011-02-28 Abbott Lab Inmunoglobulinas con dominio variable dual y usos de las mismas
AU2013204754C1 (en) * 2012-05-16 2018-10-11 Takeda Pharmaceutical Company Limited Nucleophilic Catalysts for Oxime Linkage
UY35368A (es) * 2013-03-08 2014-10-31 Irm Llc Péptidos y composiciones para el tratamiento de daño articular
MA38369B1 (fr) * 2013-03-08 2018-10-31 Novartis Ag Peptides et compositions pour le traitement d'une lesion de l'articulation
HK1224172A1 (zh) * 2013-03-15 2017-08-18 加州生物医学研究所 用於诱导软骨形成的化合物和方法
DK3143026T3 (da) * 2014-05-13 2024-09-30 Novartis Ag Forbindelser og sammensætninger til induktion af chondrogenese

Also Published As

Publication number Publication date
IL266361A (en) 2019-06-30
US20190269754A1 (en) 2019-09-05
MX2019005621A (es) 2019-08-12
CA3043667A1 (en) 2018-05-17
EP3538127A1 (en) 2019-09-18
RU2019117884A3 (https=) 2021-02-05
AU2017357785A2 (en) 2019-05-02
AU2017357785A1 (en) 2019-04-11
CN109963579A (zh) 2019-07-02
CN117860868A (zh) 2024-04-12
KR20190084287A (ko) 2019-07-16
JP2019535707A (ja) 2019-12-12
US11351223B2 (en) 2022-06-07
AU2020281098B2 (en) 2024-05-02
JP2023039962A (ja) 2023-03-22
US20220331398A1 (en) 2022-10-20
MX2022011897A (es) 2022-10-18
IL266361B2 (en) 2024-02-01
AU2020281098A1 (en) 2021-01-14
RU2019117884A (ru) 2020-12-14
IL266361B1 (en) 2023-10-01
US20250302915A1 (en) 2025-10-02
WO2018087727A1 (en) 2018-05-17

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Legal Events

Date Code Title Description
PA0104 Divisional application for international application
PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20240419

Comment text: Request for Examination of Application