KR20230145464A - 고지혈증을 치료하는 약물 조성물 및 그 제조 방법 - Google Patents

고지혈증을 치료하는 약물 조성물 및 그 제조 방법 Download PDF

Info

Publication number
KR20230145464A
KR20230145464A KR1020237031702A KR20237031702A KR20230145464A KR 20230145464 A KR20230145464 A KR 20230145464A KR 1020237031702 A KR1020237031702 A KR 1020237031702A KR 20237031702 A KR20237031702 A KR 20237031702A KR 20230145464 A KR20230145464 A KR 20230145464A
Authority
KR
South Korea
Prior art keywords
vitamin
chlorogenic acid
vitamins
trace elements
treating hyperlipidemia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
KR1020237031702A
Other languages
English (en)
Korean (ko)
Inventor
졔 장
원빈 리
왕 황
페이 장
야 장
민 쉬
Original Assignee
스촨 주장 바이오로지컬 사이언스 앤드 테크놀로지 컴퍼니 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 스촨 주장 바이오로지컬 사이언스 앤드 테크놀로지 컴퍼니 리미티드 filed Critical 스촨 주장 바이오로지컬 사이언스 앤드 테크놀로지 컴퍼니 리미티드
Publication of KR20230145464A publication Critical patent/KR20230145464A/ko
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/191—Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4415—Pyridoxine, i.e. Vitamin B6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135—Compounds containing heavy metals
    • A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/32—Manganese; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/34—Copper; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020237031702A 2021-05-11 2022-05-09 고지혈증을 치료하는 약물 조성물 및 그 제조 방법 Pending KR20230145464A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN202110509462.6 2021-05-11
CN202110509462.6A CN113143962B (zh) 2021-05-11 2021-05-11 一种治疗高脂血症的药物组合物及其制备方法
PCT/CN2022/091766 WO2022237731A1 (zh) 2021-05-11 2022-05-09 一种治疗高脂血症的药物组合物及其制备方法

Publications (1)

Publication Number Publication Date
KR20230145464A true KR20230145464A (ko) 2023-10-17

Family

ID=76874714

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020237031702A Pending KR20230145464A (ko) 2021-05-11 2022-05-09 고지혈증을 치료하는 약물 조성물 및 그 제조 방법

Country Status (5)

Country Link
US (1) US20240197665A1 (https=)
JP (1) JP2024518060A (https=)
KR (1) KR20230145464A (https=)
CN (1) CN113143962B (https=)
WO (1) WO2022237731A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113143962B (zh) * 2021-05-11 2022-08-05 四川九章生物科技有限公司 一种治疗高脂血症的药物组合物及其制备方法

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6041611A (ja) * 1983-08-17 1985-03-05 Sankyo Co Ltd 血中脂質低下剤
WO2000015215A1 (en) * 1998-09-15 2000-03-23 Korea Research Institute Of Bioscience And Biotechnology Composition containing cinnamic acid derivatives for preventing or treating elevated blood lipid level-related diseases
US20020193323A1 (en) * 2000-11-22 2002-12-19 Inna Yegorova Compositions and methods for promoting a healthy cardiovascular system and enhancing blood flow
US6632459B2 (en) * 2000-12-11 2003-10-14 Nutricia N.V. Chlorogenic acid and an analog thereof for immune system stimulation
JP4205870B2 (ja) * 2001-04-13 2009-01-07 花王株式会社 生活習慣病予防・改善剤
JP4179765B2 (ja) * 2001-07-19 2008-11-12 花王株式会社 脂質代謝改善剤
US6592896B2 (en) * 2001-08-06 2003-07-15 The Quigley Corporation Medicinal composition and method of using it
US7332181B1 (en) * 2003-09-05 2008-02-19 Glu-Pro, Inc. Composition for managing diabetes, obesity, and hyperlipidemia and associated methods
JP2006104182A (ja) * 2004-05-14 2006-04-20 Toyo Shinyaku:Kk 体脂肪低減組成物
US20080286254A1 (en) * 2007-05-17 2008-11-20 Kaneka Corporation Composition comprising licorice polyphenol
CN101766274B (zh) * 2010-01-05 2012-10-31 杭州尤美特科技有限公司 含竹叶黄酮的抗氧化功能食品组合物
US8372447B2 (en) * 2010-08-03 2013-02-12 Northern Innovations And Formulations Corp. Compositions and methods for promoting weight loss and increasing energy
EP3040067A4 (en) * 2013-08-21 2017-03-22 Sichuan Jiuzhang Biological Science And Technology Co., Ltd Chlorogenic acid powder-injection and preparation method thereof
DE102014100534A1 (de) * 2014-01-17 2015-07-23 Pm-International Ag Pulverförmige Zusammensetzung zur Herstellung eines Nahrungsmittelersatzes
US20150335604A1 (en) * 2014-05-22 2015-11-26 Boresha International Chromium and Chlorogenic Acid Weight Control Formulations
IL282156B (en) * 2014-07-29 2022-07-01 Shenzhen Hightide Biopharmaceutical Ltd Berberine salts, ursodeoxycholic salts and combinations, methods of preparation and application thereof
US20180235917A1 (en) * 2014-09-24 2018-08-23 Nusirt Sciences, Inc. Compositions, methods and kits for treatment of diabetes and/or hyperlipidemia
CN104352457A (zh) * 2014-11-24 2015-02-18 四川九章生物科技有限公司 一种包含绿原酸晶型的制剂及其用途
CN104739818A (zh) * 2015-02-13 2015-07-01 四川九章生物科技有限公司 绿原酸在制备治疗病理性黄疸的药物中的用途
JP2020519688A (ja) * 2017-05-12 2020-07-02 ハウジー ファーマシューティカル リサーチ ラボラトリーズ、エル．エル．シー． 抗糖尿病活性および他の有用な活性を有する植物抽出物
CN107661409A (zh) * 2017-11-25 2018-02-06 衡阳县华盛达农林科技有限公司 一种治疗心脑血管疾病的芦丁口服液及其制备方法
CN108208838A (zh) * 2018-03-09 2018-06-29 北京素维生物科技有限公司 一种掩味组合物及其用途
CN110448659A (zh) * 2018-05-07 2019-11-15 新疆吉盛元沙棘生物科技有限公司 沙棘护肝含片制备方法
CN108498497B (zh) * 2018-06-01 2020-05-01 四川九章生物科技有限公司 用于治疗肾癌的药物组合物及其应用
CN110141581A (zh) * 2019-05-29 2019-08-20 山东腾贵医药有限公司 一种辅助治疗三高的维生素矿物质营养组合物及其制备方法
CN111195298B (zh) * 2020-02-17 2021-12-24 集美大学 一种调节肠道菌群和防治食物过敏的组合物及其制备方法
CN112341355B (zh) * 2020-11-09 2022-08-30 中国医学科学院药用植物研究所 一种绿原酸衍生物及其制备方法和应用
CN113143962B (zh) * 2021-05-11 2022-08-05 四川九章生物科技有限公司 一种治疗高脂血症的药物组合物及其制备方法

Also Published As

Publication number Publication date
CN113143962A (zh) 2021-07-23
JP2024518060A (ja) 2024-04-24
US20240197665A1 (en) 2024-06-20
CN113143962B (zh) 2022-08-05
WO2022237731A1 (zh) 2022-11-17

Similar Documents

Publication Publication Date Title
EP2011500B1 (en) Fat accumulation inhibitor for the treatment of metabolic syndrome
DE69905214T2 (de) Mittel zur Behandlung der Osteoporose
WO2016000637A1 (zh) 一种降血脂组合物及其应用
CN110710660A (zh) 含有苦瓜粉的降低血糖组合物及膳食补充剂
CN106617072A (zh) 一种植物甾醇复合降脂组方及其片剂制备方法
KR20230145464A (ko) 고지혈증을 치료하는 약물 조성물 및 그 제조 방법
CN101057674B (zh) 一种用于防治糖尿病的组合物
CN107537028B (zh) 一种同时辅助降血糖及降血压的配方及其制备方法
CN106380459A (zh) 一种降脂的黄酮类化合物
KR101859166B1 (ko) 인삼이 함유된 한약재 추출물을 유효성분으로 함유하는 숙취 해소용 조성물
CN106232114A (zh) 周围神经病变的预防或改善用组合物
DE102008059070B4 (de) Zusammensetzung zur therapeutischen oder prophylaktischen Behandlung von Durchfallerkrankungen und/oder zur Aufrechterhaltung und/oder Wiederherstellung der natürlichen Darmflora, Dosiereinheit, Verpackungseinheit und Verwendung der Zusammensetzung
WO2020063262A1 (en) Application of 3'-deoxyinosine in preparation of drug, food or health product for multiple disease
CN101301284B (zh) 大黄酸或其盐在制备治疗慢性肾炎或慢性肾功能衰竭药物中的应用
CN110384240A (zh) 降血糖的维生素和益生菌发酵物粉营养组合物及其应用
CN1168462C (zh) 一种可降血脂、改善心肌缺血及心肌梗塞症状的口服液
CN110960502A (zh) 一种治疗代谢综合征的物质及其应用
KR101054808B1 (ko) 폴리감마글루탐산을 함유하는 혈중 콜레스테롤 함량 개선용 조성물
CN102631370B (zh) 一种预防或改善高脂血症及补充维生素d的组合物
CN114366764A (zh) 一种提高人体免疫力，预防和/或治疗骨关节炎的组合物
WO2020020317A1 (zh) 二甲双胍复配组合物及其应用
EP1408992A2 (de) Verwendung einer calciumhaltigen pharmazeutischen zusammensetzung zur behandlung von hypercholesterinämie
CN116036046A (zh) 一种包含五味子木脂素类化合物的固体脂质纳米颗粒及其制备方法和应用
CN121153858A (zh) 一种基于海参肽的降血脂复配物及其制备方法和应用
CN121177384A (zh) 辅助维持血脂健康的组合物及其制备方法

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

D21 Rejection of application intended

Free format text: ST27 STATUS EVENT CODE: A-1-2-D10-D21-EXM-PE0902 (AS PROVIDED BY THE NATIONAL OFFICE)

PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

E13 Pre-grant limitation requested

Free format text: ST27 STATUS EVENT CODE: A-2-3-E10-E13-LIM-X000 (AS PROVIDED BY THE NATIONAL OFFICE)

E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11 Amendment of application requested

Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P11-NAP-X000 (AS PROVIDED BY THE NATIONAL OFFICE)

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000