KR20230018490A - 유착 방지제 및 그것을 이용한 유착 방지 방법 - Google Patents

유착 방지제 및 그것을 이용한 유착 방지 방법 Download PDF

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Publication number
KR20230018490A
KR20230018490A KR1020227046355A KR20227046355A KR20230018490A KR 20230018490 A KR20230018490 A KR 20230018490A KR 1020227046355 A KR1020227046355 A KR 1020227046355A KR 20227046355 A KR20227046355 A KR 20227046355A KR 20230018490 A KR20230018490 A KR 20230018490A
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KR
South Korea
Prior art keywords
anionized
adhesion
group
adhesion agent
dispersion
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Abandoned
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KR1020227046355A
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English (en)
Korean (ko)
Inventor
아츠시 오하타
히로미치 야마시타
시오리 후지모토
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가부시키가이샤 오츠까 세이야꾸 고죠
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Publication of KR20230018490A publication Critical patent/KR20230018490A/ko
Abandoned legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/722Chitin, chitosan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/042Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/717Celluloses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/731Cellulose; Quaternized cellulose derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007Drug-containing films, membranes or sheets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/12Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/12Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Materials Engineering (AREA)
  • Composite Materials (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Birds (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Sealing Material Composition (AREA)
  • Paints Or Removers (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
KR1020227046355A 2020-06-01 2021-06-01 유착 방지제 및 그것을 이용한 유착 방지 방법 Abandoned KR20230018490A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JPJP-P-2020-095280 2020-06-01
JP2020095280 2020-06-01
PCT/JP2021/020791 WO2021246388A1 (ja) 2020-06-01 2021-06-01 癒着防止剤及びそれを用いた癒着防止方法

Publications (1)

Publication Number Publication Date
KR20230018490A true KR20230018490A (ko) 2023-02-07

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ID=78831085

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020227046355A Abandoned KR20230018490A (ko) 2020-06-01 2021-06-01 유착 방지제 및 그것을 이용한 유착 방지 방법

Country Status (13)

Country Link
US (1) US20230226098A1 (https=)
EP (1) EP4159251A4 (https=)
JP (2) JP7321610B2 (https=)
KR (1) KR20230018490A (https=)
CN (1) CN115884800A (https=)
AR (1) AR122491A1 (https=)
AU (1) AU2021284433A1 (https=)
BR (1) BR112022022193A2 (https=)
CA (1) CA3189526A1 (https=)
MX (1) MX2022015193A (https=)
TW (1) TW202210113A (https=)
WO (1) WO2021246388A1 (https=)
ZA (1) ZA202211627B (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7832428B2 (ja) * 2021-02-26 2026-03-18 国立大学法人信州大学 表面修飾多糖類ナノ材料、その分散液、機能性物品及び機能性物品の加工法
CN114904053A (zh) * 2022-05-31 2022-08-16 重庆大学 一种基于纤维素纳米晶的抗炎防组织粘连生物涂层及其制备方法和应用
DE102023116601A1 (de) 2022-06-29 2024-01-04 Semiconductor Energy Laboratory Co., Ltd. Licht emittierende Vorrichtung

Citations (3)

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JP2010080264A (ja) 2008-09-26 2010-04-08 Furukawa Battery Co Ltd:The 蓄電池用モノブロック電槽
JP2015099083A (ja) 2013-11-19 2015-05-28 三菱重工業株式会社 酸露点腐食評価装置及び酸露点腐食評価方法
KR20190015564A (ko) 2016-07-21 2019-02-13 난징 산홈 팔마세우티칼 컴퍼니 리미티드 이소시트레이트 탈수소효소 억제제의 화학적 화합물 및 이의 적용

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US6610669B1 (en) * 1987-09-18 2003-08-26 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
DE69015775T2 (de) * 1989-10-31 1995-05-11 Howmedica Chitinderivate enthaltende Zusammensetzungen zur Verhütung der Adhäsion.
JP3545790B2 (ja) 1993-09-30 2004-07-21 味の素ファルマ株式会社 腹腔内の癒着防止剤
WO2005000374A1 (ja) * 2003-06-30 2005-01-06 Denki Kagaku Kogyo Kabushiki Kaisha 脊椎・脊髄手術用癒着防止材
JP4998981B2 (ja) 2006-06-20 2012-08-15 国立大学法人 東京大学 微細セルロース繊維
RU2012146357A (ru) * 2010-03-31 2014-05-10 Хоги Медикал Ко., Лтд. Предотвращающий адгезию материал
WO2013047218A1 (ja) * 2011-09-30 2013-04-04 日本製紙株式会社 セルロースナノファイバーの製造方法
JP6199858B2 (ja) * 2012-03-14 2017-09-20 日本製紙株式会社 アニオン変性セルロースナノファイバー分散液の製造方法
JP5921960B2 (ja) 2012-06-04 2016-05-24 第一工業製薬株式会社 無機微粒子含有組成物およびそれを用いた被膜
EP2998435B1 (en) 2013-05-16 2021-10-13 Oji Holdings Corporation Phosphoric acid esterified cellulose fibers and production method thereof
WO2015099083A1 (ja) * 2013-12-25 2015-07-02 日産化学工業株式会社 血清および血液を固化する水分散液
JP2017155024A (ja) 2016-03-04 2017-09-07 株式会社ユーグレナ 細胞増殖促進剤
CA3049855C (en) 2017-01-16 2022-06-14 Kri, Inc. Sulfuric acid esterification modified cellulose nanofibers and method for producing cellulose nanofibers
JP6958799B2 (ja) * 2017-05-25 2021-11-02 日本製紙株式会社 ハイドロゲル
CN110520448B (zh) 2017-06-16 2023-04-07 东亚合成株式会社 纤维素纳米纤维的制造方法
KR102031178B1 (ko) * 2017-07-14 2019-10-11 순천향대학교 산학협력단 주입형 온도감응성 목재 기반 산화 나노 셀룰로오스를 포함한 유착 방지제
SI3533458T1 (sl) * 2018-03-02 2023-09-29 Upm-Kymmene Corporation Medicinski izdelek, ki vsebuje bioaktivno molekulo, ki je imobilizirana na nanofibrilarno celulozo in postopek za njegovo pripravo
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Publication number Priority date Publication date Assignee Title
JP2010080264A (ja) 2008-09-26 2010-04-08 Furukawa Battery Co Ltd:The 蓄電池用モノブロック電槽
JP2015099083A (ja) 2013-11-19 2015-05-28 三菱重工業株式会社 酸露点腐食評価装置及び酸露点腐食評価方法
KR20190015564A (ko) 2016-07-21 2019-02-13 난징 산홈 팔마세우티칼 컴퍼니 리미티드 이소시트레이트 탈수소효소 억제제의 화학적 화합물 및 이의 적용

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비특허문헌 2 : Materials Science and Engineering C 102(2019) 12-21

Also Published As

Publication number Publication date
AR122491A1 (es) 2022-09-14
JP7321610B2 (ja) 2023-08-07
EP4159251A4 (en) 2024-06-19
US20230226098A1 (en) 2023-07-20
TW202210113A (zh) 2022-03-16
JPWO2021246388A1 (https=) 2021-12-09
MX2022015193A (es) 2023-01-04
EP4159251A1 (en) 2023-04-05
BR112022022193A2 (pt) 2022-12-13
CA3189526A1 (en) 2021-12-09
JP2023096193A (ja) 2023-07-06
AU2021284433A1 (en) 2022-12-01
WO2021246388A1 (ja) 2021-12-09
ZA202211627B (en) 2024-02-28
CN115884800A (zh) 2023-03-31

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Patent event date: 20221229

Patent event code: PA01051R01D

Comment text: International Patent Application

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Patent event code: PA02012R01D

Patent event date: 20240529

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PC1902 Submission of document of abandonment before decision of registration