JP7321610B2 - 癒着防止剤及びそれを用いた癒着防止方法 - Google Patents

癒着防止剤及びそれを用いた癒着防止方法 Download PDF

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JP7321610B2
JP7321610B2 JP2022528834A JP2022528834A JP7321610B2 JP 7321610 B2 JP7321610 B2 JP 7321610B2 JP 2022528834 A JP2022528834 A JP 2022528834A JP 2022528834 A JP2022528834 A JP 2022528834A JP 7321610 B2 JP7321610 B2 JP 7321610B2
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anionized
group
adhesion
nanomaterial
dispersion
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JPWO2021246388A5 (https=
JPWO2021246388A1 (https=
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淳 大畑
拓道 山下
栞理 藤本
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Otsuka Pharmaceutical Factory Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/722—Chitin, chitosan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/042—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/717—Celluloses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/731—Cellulose; Quaternized cellulose derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/12—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/12—Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Materials Engineering (AREA)
  • Composite Materials (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Birds (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Sealing Material Composition (AREA)
  • Paints Or Removers (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
JP2022528834A 2020-06-01 2021-06-01 癒着防止剤及びそれを用いた癒着防止方法 Active JP7321610B2 (ja)

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JP2023084182A JP2023096193A (ja) 2020-06-01 2023-05-22 分散液及びその製造方法

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JP2020095280 2020-06-01
JP2020095280 2020-06-01
PCT/JP2021/020791 WO2021246388A1 (ja) 2020-06-01 2021-06-01 癒着防止剤及びそれを用いた癒着防止方法

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JPWO2021246388A1 JPWO2021246388A1 (https=) 2021-12-09
JPWO2021246388A5 JPWO2021246388A5 (https=) 2022-10-05
JP7321610B2 true JP7321610B2 (ja) 2023-08-07

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JP2023084182A Pending JP2023096193A (ja) 2020-06-01 2023-05-22 分散液及びその製造方法

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US (1) US20230226098A1 (https=)
EP (1) EP4159251A4 (https=)
JP (2) JP7321610B2 (https=)
KR (1) KR20230018490A (https=)
CN (1) CN115884800A (https=)
AR (1) AR122491A1 (https=)
AU (1) AU2021284433A1 (https=)
BR (1) BR112022022193A2 (https=)
CA (1) CA3189526A1 (https=)
MX (1) MX2022015193A (https=)
TW (1) TW202210113A (https=)
WO (1) WO2021246388A1 (https=)
ZA (1) ZA202211627B (https=)

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JP7832428B2 (ja) * 2021-02-26 2026-03-18 国立大学法人信州大学 表面修飾多糖類ナノ材料、その分散液、機能性物品及び機能性物品の加工法
CN114904053A (zh) * 2022-05-31 2022-08-16 重庆大学 一种基于纤维素纳米晶的抗炎防组织粘连生物涂层及其制备方法和应用
DE102023116601A1 (de) 2022-06-29 2024-01-04 Semiconductor Energy Laboratory Co., Ltd. Licht emittierende Vorrichtung

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WO2005000374A1 (ja) 2003-06-30 2005-01-06 Denki Kagaku Kogyo Kabushiki Kaisha 脊椎・脊髄手術用癒着防止材
WO2015099083A1 (ja) 2013-12-25 2015-07-02 日産化学工業株式会社 血清および血液を固化する水分散液
US20190015564A1 (en) 2017-07-14 2019-01-17 Soonchunhyang University Industry Academy Cooperation Foundation Adhesion prevention agent comprising injectable thermosensitive wood based-oxidized cellulose nanofiber

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JP3545790B2 (ja) 1993-09-30 2004-07-21 味の素ファルマ株式会社 腹腔内の癒着防止剤
JP4998981B2 (ja) 2006-06-20 2012-08-15 国立大学法人 東京大学 微細セルロース繊維
JP5001246B2 (ja) 2008-09-26 2012-08-15 古河電池株式会社 蓄電池用モノブロック電槽
RU2012146357A (ru) * 2010-03-31 2014-05-10 Хоги Медикал Ко., Лтд. Предотвращающий адгезию материал
WO2013047218A1 (ja) * 2011-09-30 2013-04-04 日本製紙株式会社 セルロースナノファイバーの製造方法
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WO2015099083A1 (ja) 2013-12-25 2015-07-02 日産化学工業株式会社 血清および血液を固化する水分散液
US20190015564A1 (en) 2017-07-14 2019-01-17 Soonchunhyang University Industry Academy Cooperation Foundation Adhesion prevention agent comprising injectable thermosensitive wood based-oxidized cellulose nanofiber

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KR20230018490A (ko) 2023-02-07
AR122491A1 (es) 2022-09-14
EP4159251A4 (en) 2024-06-19
US20230226098A1 (en) 2023-07-20
TW202210113A (zh) 2022-03-16
JPWO2021246388A1 (https=) 2021-12-09
MX2022015193A (es) 2023-01-04
EP4159251A1 (en) 2023-04-05
BR112022022193A2 (pt) 2022-12-13
CA3189526A1 (en) 2021-12-09
JP2023096193A (ja) 2023-07-06
AU2021284433A1 (en) 2022-12-01
WO2021246388A1 (ja) 2021-12-09
ZA202211627B (en) 2024-02-28
CN115884800A (zh) 2023-03-31

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