CN115884800A - 防粘连剂及使用其的粘连防止方法 - Google Patents

防粘连剂及使用其的粘连防止方法 Download PDF

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Publication number
CN115884800A
CN115884800A CN202180039187.4A CN202180039187A CN115884800A CN 115884800 A CN115884800 A CN 115884800A CN 202180039187 A CN202180039187 A CN 202180039187A CN 115884800 A CN115884800 A CN 115884800A
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CN
China
Prior art keywords
anionized
group
adhesion
chitin
dispersion
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Pending
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CN202180039187.4A
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English (en)
Chinese (zh)
Inventor
大畑淳
山下拓道
藤本栞理
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Otsuka Pharmaceutical Factory Inc
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Otsuka Pharmaceutical Factory Inc
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Publication of CN115884800A publication Critical patent/CN115884800A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/722—Chitin, chitosan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/042—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/717—Celluloses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/731—Cellulose; Quaternized cellulose derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/12—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/12—Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Materials Engineering (AREA)
  • Composite Materials (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Birds (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Sealing Material Composition (AREA)
  • Paints Or Removers (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
CN202180039187.4A 2020-06-01 2021-06-01 防粘连剂及使用其的粘连防止方法 Pending CN115884800A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020095280 2020-06-01
JP2020-095280 2020-06-01
PCT/JP2021/020791 WO2021246388A1 (ja) 2020-06-01 2021-06-01 癒着防止剤及びそれを用いた癒着防止方法

Publications (1)

Publication Number Publication Date
CN115884800A true CN115884800A (zh) 2023-03-31

Family

ID=78831085

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180039187.4A Pending CN115884800A (zh) 2020-06-01 2021-06-01 防粘连剂及使用其的粘连防止方法

Country Status (13)

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US (1) US20230226098A1 (https=)
EP (1) EP4159251A4 (https=)
JP (2) JP7321610B2 (https=)
KR (1) KR20230018490A (https=)
CN (1) CN115884800A (https=)
AR (1) AR122491A1 (https=)
AU (1) AU2021284433A1 (https=)
BR (1) BR112022022193A2 (https=)
CA (1) CA3189526A1 (https=)
MX (1) MX2022015193A (https=)
TW (1) TW202210113A (https=)
WO (1) WO2021246388A1 (https=)
ZA (1) ZA202211627B (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7832428B2 (ja) * 2021-02-26 2026-03-18 国立大学法人信州大学 表面修飾多糖類ナノ材料、その分散液、機能性物品及び機能性物品の加工法
CN114904053A (zh) * 2022-05-31 2022-08-16 重庆大学 一种基于纤维素纳米晶的抗炎防组织粘连生物涂层及其制备方法和应用
DE102023116601A1 (de) 2022-06-29 2024-01-04 Semiconductor Energy Laboratory Co., Ltd. Licht emittierende Vorrichtung

Citations (5)

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CN103827146A (zh) * 2011-09-30 2014-05-28 日本制纸株式会社 纤维素纳米纤维的制造方法
CN104169306A (zh) * 2012-03-14 2014-11-26 日本制纸株式会社 阴离子改性纤维素纳米纤维分散液的制造方法
WO2015099083A1 (ja) * 2013-12-25 2015-07-02 日産化学工業株式会社 血清および血液を固化する水分散液
JP2018199753A (ja) * 2017-05-25 2018-12-20 日本製紙株式会社 ハイドロゲル及びその製造方法
US20190015564A1 (en) * 2017-07-14 2019-01-17 Soonchunhyang University Industry Academy Cooperation Foundation Adhesion prevention agent comprising injectable thermosensitive wood based-oxidized cellulose nanofiber

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US6610669B1 (en) * 1987-09-18 2003-08-26 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
DE69015775T2 (de) * 1989-10-31 1995-05-11 Howmedica Chitinderivate enthaltende Zusammensetzungen zur Verhütung der Adhäsion.
JP3545790B2 (ja) 1993-09-30 2004-07-21 味の素ファルマ株式会社 腹腔内の癒着防止剤
WO2005000374A1 (ja) * 2003-06-30 2005-01-06 Denki Kagaku Kogyo Kabushiki Kaisha 脊椎・脊髄手術用癒着防止材
JP4998981B2 (ja) 2006-06-20 2012-08-15 国立大学法人 東京大学 微細セルロース繊維
JP5001246B2 (ja) 2008-09-26 2012-08-15 古河電池株式会社 蓄電池用モノブロック電槽
RU2012146357A (ru) * 2010-03-31 2014-05-10 Хоги Медикал Ко., Лтд. Предотвращающий адгезию материал
JP5921960B2 (ja) 2012-06-04 2016-05-24 第一工業製薬株式会社 無機微粒子含有組成物およびそれを用いた被膜
EP2998435B1 (en) 2013-05-16 2021-10-13 Oji Holdings Corporation Phosphoric acid esterified cellulose fibers and production method thereof
JP2015099083A (ja) 2013-11-19 2015-05-28 三菱重工業株式会社 酸露点腐食評価装置及び酸露点腐食評価方法
JP2017155024A (ja) 2016-03-04 2017-09-07 株式会社ユーグレナ 細胞増殖促進剤
KR102232614B1 (ko) 2016-07-21 2021-03-29 난징 산홈 팔마세우티칼 컴퍼니 리미티드 이소시트레이트 탈수소효소 억제제의 화학적 화합물 및 이의 적용
CA3049855C (en) 2017-01-16 2022-06-14 Kri, Inc. Sulfuric acid esterification modified cellulose nanofibers and method for producing cellulose nanofibers
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CN103827146A (zh) * 2011-09-30 2014-05-28 日本制纸株式会社 纤维素纳米纤维的制造方法
CN104169306A (zh) * 2012-03-14 2014-11-26 日本制纸株式会社 阴离子改性纤维素纳米纤维分散液的制造方法
WO2015099083A1 (ja) * 2013-12-25 2015-07-02 日産化学工業株式会社 血清および血液を固化する水分散液
JP2018199753A (ja) * 2017-05-25 2018-12-20 日本製紙株式会社 ハイドロゲル及びその製造方法
US20190015564A1 (en) * 2017-07-14 2019-01-17 Soonchunhyang University Industry Academy Cooperation Foundation Adhesion prevention agent comprising injectable thermosensitive wood based-oxidized cellulose nanofiber

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Publication number Publication date
KR20230018490A (ko) 2023-02-07
AR122491A1 (es) 2022-09-14
JP7321610B2 (ja) 2023-08-07
EP4159251A4 (en) 2024-06-19
US20230226098A1 (en) 2023-07-20
TW202210113A (zh) 2022-03-16
JPWO2021246388A1 (https=) 2021-12-09
MX2022015193A (es) 2023-01-04
EP4159251A1 (en) 2023-04-05
BR112022022193A2 (pt) 2022-12-13
CA3189526A1 (en) 2021-12-09
JP2023096193A (ja) 2023-07-06
AU2021284433A1 (en) 2022-12-01
WO2021246388A1 (ja) 2021-12-09
ZA202211627B (en) 2024-02-28

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