KR20220137033A - 부작용이 감소된 nmda 길항제 - Google Patents

부작용이 감소된 nmda 길항제 Download PDF

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Publication number
KR20220137033A
KR20220137033A KR1020227028884A KR20227028884A KR20220137033A KR 20220137033 A KR20220137033 A KR 20220137033A KR 1020227028884 A KR1020227028884 A KR 1020227028884A KR 20227028884 A KR20227028884 A KR 20227028884A KR 20220137033 A KR20220137033 A KR 20220137033A
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KR
South Korea
Prior art keywords
hours
racemic ketamine
acceptable salt
pharmaceutically acceptable
ketamine
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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KR1020227028884A
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English (en)
Korean (ko)
Inventor
라즈 메흐라
티모시 휘태커
Original Assignee
실로스 테라퓨틱스, 인크.
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Application filed by 실로스 테라퓨틱스, 인크. filed Critical 실로스 테라퓨틱스, 인크.
Publication of KR20220137033A publication Critical patent/KR20220137033A/ko
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Neurosurgery (AREA)
  • Otolaryngology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020227028884A 2020-01-22 2021-01-22 부작용이 감소된 nmda 길항제 Pending KR20220137033A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202062964598P 2020-01-22 2020-01-22
US62/964,598 2020-01-22
US202063079791P 2020-09-17 2020-09-17
US63/079,791 2020-09-17
PCT/US2021/014748 WO2021150985A1 (en) 2020-01-22 2021-01-22 Reducing side effects of nmda antagonists

Publications (1)

Publication Number Publication Date
KR20220137033A true KR20220137033A (ko) 2022-10-11

Family

ID=74672414

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020227028884A Pending KR20220137033A (ko) 2020-01-22 2021-01-22 부작용이 감소된 nmda 길항제

Country Status (14)

Country Link
US (5) US20230064327A1 (https=)
EP (1) EP4093388A1 (https=)
JP (2) JP2023511370A (https=)
KR (1) KR20220137033A (https=)
CN (2) CN115135317A (https=)
AU (1) AU2021210405A1 (https=)
BR (1) BR112022014382A2 (https=)
CA (1) CA3164022A1 (https=)
CL (1) CL2022001958A1 (https=)
IL (1) IL294485A (https=)
MX (1) MX2022009050A (https=)
PH (1) PH12022551856A1 (https=)
TW (1) TW202139981A (https=)
WO (1) WO2021150985A1 (https=)

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TW202310825A (zh) * 2021-05-14 2023-03-16 美商西羅斯醫療公司 減少ｎｍｄａ受體拮抗劑之副作用
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CN120919139A (zh) * 2025-09-09 2025-11-11 徐州百瑞麻醉科技研究院有限公司 一种抗抑郁药物组合物及其应用

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TW202139981A (zh) 2021-11-01
US20240342113A1 (en) 2024-10-17
BR112022014382A2 (pt) 2022-09-13
AU2021210405A1 (en) 2022-08-25
EP4093388A1 (en) 2022-11-30
CN121489916A (zh) 2026-02-10
JP2023511370A (ja) 2023-03-17
US20230270694A1 (en) 2023-08-31
PH12022551856A1 (en) 2024-01-03
US12440457B2 (en) 2025-10-14
JP2026050474A (ja) 2026-03-19
IL294485A (en) 2022-09-01
US20230241008A1 (en) 2023-08-03
US20230064327A1 (en) 2023-03-02
CA3164022A1 (en) 2021-07-29
MX2022009050A (es) 2022-10-27
CN115135317A (zh) 2022-09-30
WO2021150985A1 (en) 2021-07-29
CL2022001958A1 (es) 2023-05-26
US20230321007A1 (en) 2023-10-12

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