KR20220130093A - 오토펄린 듀얼 벡터 시스템을 사용한 감각신경성 난청을 치료하기 위한 조성물 및 방법 - Google Patents

오토펄린 듀얼 벡터 시스템을 사용한 감각신경성 난청을 치료하기 위한 조성물 및 방법 Download PDF

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KR20220130093A
KR20220130093A KR1020227018008A KR20227018008A KR20220130093A KR 20220130093 A KR20220130093 A KR 20220130093A KR 1020227018008 A KR1020227018008 A KR 1020227018008A KR 20227018008 A KR20227018008 A KR 20227018008A KR 20220130093 A KR20220130093 A KR 20220130093A
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sequence
seq
otof
vector system
isoform
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조셉 번즈
캐스린 엘리스
타일러 깁슨
아담 팔레르모
마르틴 슈반더
조나단 휘튼
레아 사빈
크리스토스 키라트수스
메건 드러먼드 새뮤얼슨
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데시벨 테라퓨틱스, 인크.
리제너론 파아마슈티컬스, 인크.
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    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/44—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor

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KR1020227018008A 2019-10-30 2020-10-30 오토펄린 듀얼 벡터 시스템을 사용한 감각신경성 난청을 치료하기 위한 조성물 및 방법 Pending KR20220130093A (ko)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201962928290P 2019-10-30 2019-10-30
US62/928,290 2019-10-30
US202062965776P 2020-01-24 2020-01-24
US62/965,776 2020-01-24
US202062971504P 2020-02-07 2020-02-07
US62/971,504 2020-02-07
US202063023058P 2020-05-11 2020-05-11
US63/023,058 2020-05-11
PCT/US2020/058265 WO2021087296A1 (en) 2019-10-30 2020-10-30 Compositions and methods for treating sensorineural hearing loss using otoferlin dual vector systems

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KR20220130093A true KR20220130093A (ko) 2022-09-26

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KR1020227018008A Pending KR20220130093A (ko) 2019-10-30 2020-10-30 오토펄린 듀얼 벡터 시스템을 사용한 감각신경성 난청을 치료하기 위한 조성물 및 방법

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US (1) US12589168B2 (OSRAM)
EP (1) EP4051698A4 (OSRAM)
JP (2) JP7665609B2 (OSRAM)
KR (1) KR20220130093A (OSRAM)
BR (1) BR112022008214A2 (OSRAM)
CA (1) CA3159549A1 (OSRAM)
IL (1) IL292620A (OSRAM)
MX (1) MX2022005236A (OSRAM)
TW (1) TWI896570B (OSRAM)
WO (1) WO2021087296A1 (OSRAM)

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BR112022008214A2 (pt) 2022-07-12
US20220265865A1 (en) 2022-08-25
WO2021087296A8 (en) 2021-08-05
IL292620A (en) 2022-07-01
MX2022005236A (es) 2022-06-08
JP2022554300A (ja) 2022-12-28
EP4051698A1 (en) 2022-09-07
TW202130654A (zh) 2021-08-16
US12589168B2 (en) 2026-03-31
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