KR20190127892A - 바이오마커 및 효능이 증진된 car t 세포 요법 - Google Patents

바이오마커 및 효능이 증진된 car t 세포 요법 Download PDF

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KR20190127892A
KR20190127892A KR1020197030924A KR20197030924A KR20190127892A KR 20190127892 A KR20190127892 A KR 20190127892A KR 1020197030924 A KR1020197030924 A KR 1020197030924A KR 20197030924 A KR20197030924 A KR 20197030924A KR 20190127892 A KR20190127892 A KR 20190127892A
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tet2
cell
gene
genes
car
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조셉 에이. 프라이에타
잔 제이. 멜렌호스트
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노파르티스 아게
더 트러스티스 오브 더 유니버시티 오브 펜실바니아
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KR1020197030924A 2017-03-22 2018-03-22 바이오마커 및 효능이 증진된 car t 세포 요법 Ceased KR20190127892A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762474991P 2017-03-22 2017-03-22
US62/474,991 2017-03-22
US201862621356P 2018-01-24 2018-01-24
US62/621,356 2018-01-24
PCT/US2018/023785 WO2018175733A1 (en) 2017-03-22 2018-03-22 Biomarkers and car t cell therapies with enhanced efficacy

Publications (1)

Publication Number Publication Date
KR20190127892A true KR20190127892A (ko) 2019-11-13

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KR1020197030924A Ceased KR20190127892A (ko) 2017-03-22 2018-03-22 바이오마커 및 효능이 증진된 car t 세포 요법

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Country Link
US (1) US20200087376A1 (https=)
EP (1) EP3600392A1 (https=)
JP (2) JP2020513828A (https=)
KR (1) KR20190127892A (https=)
CN (1) CN110831619A (https=)
AU (1) AU2018240295A1 (https=)
BR (1) BR112019019426A2 (https=)
CA (1) CA3057306A1 (https=)
IL (1) IL269412A (https=)
RU (1) RU2019133286A (https=)
SG (1) SG11201908719QA (https=)
WO (1) WO2018175733A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021162521A1 (ko) * 2020-02-14 2021-08-19 (주)이뮤노텍바이오팜코리아 외부에서 도입된 세포 신호 조절 인자를 과발현하는 면역 세포 및 이들의 용도
WO2023101277A1 (ko) * 2021-12-02 2023-06-08 한국화학연구원 증진된 효능을 갖는 면역세포

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US9273283B2 (en) * 2009-10-29 2016-03-01 The Trustees Of Dartmouth College Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
JP6647868B2 (ja) 2013-02-20 2020-02-14 ノバルティス アーゲー ヒト化抗ＥＧＦＲｖＩＩＩキメラ抗原受容体を用いたがんの処置
WO2014145252A2 (en) 2013-03-15 2014-09-18 Milone Michael C Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
UY35468A (es) 2013-03-16 2014-10-31 Novartis Ag Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19
EP3087101B1 (en) 2013-12-20 2024-06-05 Novartis AG Regulatable chimeric antigen receptor
WO2015112626A1 (en) 2014-01-21 2015-07-30 June Carl H Enhanced antigen presenting ability of car t cells by co-introduction of costimulatory molecules
TWI719942B (zh) 2014-07-21 2021-03-01 瑞士商諾華公司 使用ｃｄ３３嵌合抗原受體治療癌症
US11542488B2 (en) 2014-07-21 2023-01-03 Novartis Ag Sortase synthesized chimeric antigen receptors
BR112017001183A2 (pt) 2014-07-21 2017-11-28 Novartis Ag tratamento de câncer usando receptor de antígeno quimérico anti-bcma humanizado
MX2017002205A (es) 2014-08-19 2017-08-21 Novartis Ag Receptor quimerico de antigeno (car) anti-cd123 para uso en el tratamiento de cancer.
US11459390B2 (en) 2015-01-16 2022-10-04 Novartis Ag Phosphoglycerate kinase 1 (PGK) promoters and methods of use for expressing chimeric antigen receptor
WO2016126608A1 (en) 2015-02-02 2016-08-11 Novartis Ag Car-expressing cells against multiple tumor antigens and uses thereof
JP6961490B2 (ja) 2015-04-08 2021-11-05 ノバルティス アーゲー Ｃｄ２０療法、ｃｄ２２療法、およびｃｄ１９キメラ抗原受容体（ｃａｒ）発現細胞との併用療法
AU2016249005B2 (en) 2015-04-17 2022-06-16 Novartis Ag Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells
EP3286211A1 (en) 2015-04-23 2018-02-28 Novartis AG Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
CA2992551A1 (en) 2015-07-21 2017-01-26 Novartis Ag Methods for improving the efficacy and expansion of immune cells
US11667691B2 (en) 2015-08-07 2023-06-06 Novartis Ag Treatment of cancer using chimeric CD3 receptor proteins
WO2017040930A2 (en) 2015-09-03 2017-03-09 The Trustees Of The University Of Pennsylvania Biomarkers predictive of cytokine release syndrome
WO2017093969A1 (en) 2015-12-04 2017-06-08 Novartis Ag Compositions and methods for immunooncology
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