KR20190124247A - Csf1r-기반 키메라 단백질 - Google Patents
Csf1r-기반 키메라 단백질 Download PDFInfo
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- KR20190124247A KR20190124247A KR1020197027869A KR20197027869A KR20190124247A KR 20190124247 A KR20190124247 A KR 20190124247A KR 1020197027869 A KR1020197027869 A KR 1020197027869A KR 20197027869 A KR20197027869 A KR 20197027869A KR 20190124247 A KR20190124247 A KR 20190124247A
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7153—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for colony-stimulating factors [CSF]
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- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
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- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
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- C07K2319/00—Fusion polypeptide
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- C—CHEMISTRY; METALLURGY
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- C07K2319/00—Fusion polypeptide
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
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| PCT/US2018/020039 WO2018157164A1 (en) | 2017-02-27 | 2018-02-27 | Csf1r-based chimeric proteins |
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| US (4) | US11267856B2 (https=) |
| EP (1) | EP3585409A4 (https=) |
| JP (2) | JP7121029B2 (https=) |
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| CN (1) | CN110381974A (https=) |
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| BR (1) | BR112019017713A2 (https=) |
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| WO (1) | WO2018157164A1 (https=) |
| ZA (1) | ZA201906235B (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2023287049A1 (ko) * | 2021-07-14 | 2023-01-19 | 주식회사 이뮤노로지컬디자이닝랩 | Cd30에 특이적으로 결합하는 키메릭 항원 수용체 및 이의 용도 |
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| US11267856B2 (en) | 2017-02-27 | 2022-03-08 | Shattuck Labs, Inc. | CSF1R-CD40L chimeric proteins |
| EP3930851A4 (en) * | 2019-02-28 | 2023-03-29 | Shattuck Labs, Inc. | COMBINATION THERAPIES |
| US20220259281A1 (en) * | 2019-06-21 | 2022-08-18 | Shattuck Labs, Inc. | Chimeric protein expressing t-cells |
| CN111068054B (zh) * | 2019-11-06 | 2022-02-11 | 浙江大学医学院附属第一医院 | 以csf1r作为药物靶点治疗肿瘤的药剂及其制备方法 |
| CN113966230B (zh) * | 2019-12-24 | 2022-06-07 | 宝船生物医药科技(上海)有限公司 | 抗csf1r分子及其用途 |
| KR102671409B1 (ko) * | 2021-03-02 | 2024-05-31 | 진화섭 | Cd30을 발현하는 세포에 독성을 나타내는 재조합 단백질 및 이를 유효성분으로 포함하는 암의 치료용 약학적 조성물 |
| EP4305051A4 (en) * | 2021-03-08 | 2025-06-04 | Shattuck Labs, Inc. | CHIMERIC PROTEINS USEFUL IN AUTOIMMUNITY |
| WO2024123812A1 (en) | 2022-12-05 | 2024-06-13 | Shattuck Labs, Inc. | Fusion proteins for the treatment of cardiometabolic diseases |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023287049A1 (ko) * | 2021-07-14 | 2023-01-19 | 주식회사 이뮤노로지컬디자이닝랩 | Cd30에 특이적으로 결합하는 키메릭 항원 수용체 및 이의 용도 |
Also Published As
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| JP7121029B2 (ja) | 2022-08-17 |
| EP3585409A4 (en) | 2020-12-02 |
| RU2019129835A3 (https=) | 2021-07-16 |
| AU2018223822A1 (en) | 2019-07-11 |
| RU2019129835A (ru) | 2021-03-29 |
| CA3054132A1 (en) | 2018-08-30 |
| SG11201906464UA (en) | 2019-08-27 |
| IL268197A (en) | 2019-09-26 |
| JP2022159393A (ja) | 2022-10-17 |
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| BR112019017713A2 (pt) | 2020-04-07 |
| US10513548B2 (en) | 2019-12-24 |
| JP2020508063A (ja) | 2020-03-19 |
| EP3585409A1 (en) | 2020-01-01 |
| MX2019010173A (es) | 2019-11-21 |
| US20200123214A1 (en) | 2020-04-23 |
| US11267857B2 (en) | 2022-03-08 |
| US20220144909A1 (en) | 2022-05-12 |
| US11267856B2 (en) | 2022-03-08 |
| CN110381974A (zh) | 2019-10-25 |
| US20190169249A1 (en) | 2019-06-06 |
| SA519402522B1 (ar) | 2023-03-12 |
| WO2018157164A1 (en) | 2018-08-30 |
| US20190382466A1 (en) | 2019-12-19 |
| ZA201906235B (en) | 2021-04-28 |
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