KR20180098222A - 활성화된 지방산의 치료학적 유효량을 이용한 질환의 예방, 치료 및 역행 - Google Patents
활성화된 지방산의 치료학적 유효량을 이용한 질환의 예방, 치료 및 역행 Download PDFInfo
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- KR20180098222A KR20180098222A KR1020187012337A KR20187012337A KR20180098222A KR 20180098222 A KR20180098222 A KR 20180098222A KR 1020187012337 A KR1020187012337 A KR 1020187012337A KR 20187012337 A KR20187012337 A KR 20187012337A KR 20180098222 A KR20180098222 A KR 20180098222A
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- Prior art keywords
- nitro
- octadec
- enoic acid
- disease
- milligrams
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Child & Adolescent Psychology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562236702P | 2015-10-02 | 2015-10-02 | |
| US62/236,702 | 2015-10-02 | ||
| PCT/US2016/055206 WO2017059451A1 (en) | 2015-10-02 | 2016-10-03 | Prevention, treatment and reversal of disease using therapeutically effective amounts of activated fatty acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20180098222A true KR20180098222A (ko) | 2018-09-03 |
Family
ID=58428002
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020187012337A Ceased KR20180098222A (ko) | 2015-10-02 | 2016-10-03 | 활성화된 지방산의 치료학적 유효량을 이용한 질환의 예방, 치료 및 역행 |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US10537541B2 (https=) |
| EP (1) | EP3355879A4 (https=) |
| JP (2) | JP2018529779A (https=) |
| KR (1) | KR20180098222A (https=) |
| CN (2) | CN108430466A (https=) |
| AU (2) | AU2016331314A1 (https=) |
| BR (1) | BR112018006687A2 (https=) |
| CA (1) | CA3000842A1 (https=) |
| CL (1) | CL2018000835A1 (https=) |
| CO (1) | CO2018004576A2 (https=) |
| CR (1) | CR20180246A (https=) |
| EA (1) | EA201890859A1 (https=) |
| HK (1) | HK1259031A1 (https=) |
| IL (2) | IL258476B2 (https=) |
| MX (1) | MX2018004043A (https=) |
| SG (1) | SG10201913953UA (https=) |
| WO (1) | WO2017059451A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102083787A (zh) * | 2008-05-01 | 2011-06-01 | 康普雷克萨公司 | 乙烯基取代的脂肪酸 |
| US20140024713A1 (en) | 2008-06-19 | 2014-01-23 | University Of Utah Research Foundation | Use of nitrated lipids for treatment of side effects of toxic medical therapies |
| HRP20240082T1 (hr) | 2015-07-07 | 2024-03-29 | H. Lundbeck A/S | Inhibitor pde9 s okosnicom imidazopirazinona za liječenje perifernih bolesti |
| IL258476B2 (en) * | 2015-10-02 | 2023-04-01 | Complexa Inc | Prevention, treatment and reversal of disease using therapeutically effective amounts of activated fatty acids |
| FI3801526T3 (fi) | 2018-05-25 | 2024-03-20 | Cardurion Pharmaceuticals Inc | 6-[(3s,4s)-4-metyyli-1-(pyrimidin-2-yylimetyyli)pyrrolidin-3-yyli]-3-tetrahydropyran-4-yyli-7h-imidatso[1,5-a]pyratsin-8-onin monohydraattimuotoja ja kiteisiä muotoja |
| EP3843737A4 (en) | 2018-08-31 | 2022-06-01 | Imara Inc. | PDE9 INHIBITORS FOR THE TREATMENT OF SICKLE CELL DISEASE |
| CN111229117B (zh) * | 2018-11-29 | 2022-01-04 | 中国石油化工股份有限公司 | 含脂肪酸型表面活性剂的混合体系及其制备方法 |
| CN111229120B (zh) * | 2018-11-29 | 2022-01-07 | 中国石油化工股份有限公司 | 含脂肪酸型表面活性剂的混合体系及其制备方法 |
| FR3092968B1 (fr) * | 2019-02-22 | 2021-05-21 | Microphyt | Complement alimentaire |
| CN110157792A (zh) * | 2019-04-22 | 2019-08-23 | 中山大学孙逸仙纪念医院 | 血清外泌体has_circ_0004771在制备酒精依赖综合征诊断试剂中的应用 |
| WO2021242758A1 (en) * | 2020-05-26 | 2021-12-02 | Imara Inc. | Improved nitro-fatty acid oral dose regimens |
| WO2023014748A1 (en) * | 2021-08-03 | 2023-02-09 | Imara Inc. | Nitrated fatty acids for the treatment of sickle cell disorders |
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| WO2016161285A1 (en) * | 2015-04-02 | 2016-10-06 | Aobiome Llc | Production of nitro-fatty acids and nitro-hydrocarbons by ammonia oxidizing bacteria |
| IL258476B2 (en) * | 2015-10-02 | 2023-04-01 | Complexa Inc | Prevention, treatment and reversal of disease using therapeutically effective amounts of activated fatty acids |
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2016
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- 2016-10-03 CN CN201680070797.XA patent/CN108430466A/zh active Pending
- 2016-10-03 EP EP16852846.1A patent/EP3355879A4/en not_active Withdrawn
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- 2016-10-03 US US15/283,887 patent/US10537541B2/en not_active Expired - Fee Related
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- 2016-10-03 HK HK19101519.9A patent/HK1259031A1/zh unknown
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- 2016-10-03 WO PCT/US2016/055206 patent/WO2017059451A1/en not_active Ceased
- 2016-10-03 CA CA3000842A patent/CA3000842A1/en not_active Abandoned
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2018
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2019
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2021
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Also Published As
| Publication number | Publication date |
|---|---|
| JP2021183640A (ja) | 2021-12-02 |
| CR20180246A (es) | 2018-11-22 |
| BR112018006687A2 (pt) | 2018-10-09 |
| AU2016331314A1 (en) | 2018-05-17 |
| JP2018529779A (ja) | 2018-10-11 |
| IL258476A (en) | 2018-06-28 |
| IL258476B (en) | 2022-12-01 |
| WO2017059451A1 (en) | 2017-04-06 |
| CO2018004576A2 (es) | 2018-07-19 |
| CN108430466A (zh) | 2018-08-21 |
| CA3000842A1 (en) | 2017-04-06 |
| IL258476B2 (en) | 2023-04-01 |
| AU2021205027A1 (en) | 2021-08-12 |
| EP3355879A4 (en) | 2019-05-22 |
| MX2018004043A (es) | 2018-11-09 |
| HK1259031A1 (zh) | 2019-11-22 |
| US10537541B2 (en) | 2020-01-21 |
| SG10201913953UA (en) | 2020-03-30 |
| US20200046669A1 (en) | 2020-02-13 |
| CL2018000835A1 (es) | 2018-09-14 |
| EP3355879A1 (en) | 2018-08-08 |
| US20170095437A1 (en) | 2017-04-06 |
| EA201890859A1 (ru) | 2018-11-30 |
| US20220000824A1 (en) | 2022-01-06 |
| CN113440506A (zh) | 2021-09-28 |
| IL297844A (en) | 2023-01-01 |
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