KR20180086508A - 치환된 5,6-디하이드로-6-페닐벤조[f]이소퀴놀린-2-아민 화합물의 고체 형태 - Google Patents
치환된 5,6-디하이드로-6-페닐벤조[f]이소퀴놀린-2-아민 화합물의 고체 형태 Download PDFInfo
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- KR20180086508A KR20180086508A KR1020187020340A KR20187020340A KR20180086508A KR 20180086508 A KR20180086508 A KR 20180086508A KR 1020187020340 A KR1020187020340 A KR 1020187020340A KR 20187020340 A KR20187020340 A KR 20187020340A KR 20180086508 A KR20180086508 A KR 20180086508A
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- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
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- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
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| PCT/US2016/067164 WO2017106642A1 (en) | 2015-12-17 | 2016-12-16 | Solid forms of substituted 5,6-dihydro-6-phenylbenzo[f]isoquinolin-2-amine compounds |
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| TWI771280B (zh) | 2015-12-17 | 2022-07-21 | 美商亞闊股份有限公司 | 經取代之5,6-二氫-6-苯基苯并[f]異喹啉-2-胺化合物之固體形式 |
| WO2022053708A1 (en) | 2020-09-14 | 2022-03-17 | Basilea Pharmaceutica International AG | Pharmaceutical combinations for use in the treatment of gastric adenocarcinoma |
| JP7641247B2 (ja) | 2022-03-02 | 2025-03-06 | 日立建機株式会社 | 機械の性能診断装置 |
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| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| WO1998028281A1 (en) | 1996-12-23 | 1998-07-02 | Celltech Therapeutics Limited | Fused polycyclic 2-aminopyrimidine derivatives, their preparation and their use as protein tyrosine kinase inhibitors |
| GB9713087D0 (en) * | 1997-06-20 | 1997-08-27 | Celltech Therapeutics Ltd | Chemical compounds |
| EP1638937B1 (en) * | 2003-06-18 | 2008-12-17 | Teva Pharmaceutical Industries Limited | Fluvastatin sodium crystal form xiv, processes for preparing it, compositions containing it and methods of using it |
| EP2079736B1 (en) * | 2006-12-29 | 2017-10-18 | Rigel Pharmaceuticals, Inc. | Substituted triazoles useful as axl inhibitors |
| MX2011006959A (es) * | 2008-12-30 | 2011-12-06 | Arqule Inc | Compuestos substituidos de 5,6-dihidro-6-fenilbenzo [f] isoquinolina-2-amina. |
| KR20130105675A (ko) * | 2010-11-25 | 2013-09-25 | 라티오팜 게엠베하 | 아파티닙의 신규 염 및 다형 |
| WO2012177852A1 (en) * | 2011-06-24 | 2012-12-27 | Arqule, Inc | Substituted imidazopyridinyl compounds |
| US9802954B2 (en) * | 2011-08-24 | 2017-10-31 | Boehringer Ingelheim International Gmbh | Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma |
| EP2760859A1 (en) * | 2011-09-30 | 2014-08-06 | Sunshine Lake Pharma Co., Ltd | Crystalline forms of azilsartan and preparation and uses thereof |
| TWI771280B (zh) * | 2015-12-17 | 2022-07-21 | 美商亞闊股份有限公司 | 經取代之5,6-二氫-6-苯基苯并[f]異喹啉-2-胺化合物之固體形式 |
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| US9847831B2 (en) | 2016-04-08 | 2017-12-19 | Ciena Corporation | Dual wavelenth optical time domain reflectometer systems and methods embedded in a WDM system |
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