KR20170125941A - 개선된 반감기를 갖는 변형된 폰 빌레브란트 인자 - Google Patents
개선된 반감기를 갖는 변형된 폰 빌레브란트 인자 Download PDFInfo
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- KR20170125941A KR20170125941A KR1020177028206A KR20177028206A KR20170125941A KR 20170125941 A KR20170125941 A KR 20170125941A KR 1020177028206 A KR1020177028206 A KR 1020177028206A KR 20177028206 A KR20177028206 A KR 20177028206A KR 20170125941 A KR20170125941 A KR 20170125941A
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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| EP15158065 | 2015-03-06 | ||
| EP15158065.1 | 2015-03-06 | ||
| PCT/EP2016/054647 WO2016142288A1 (en) | 2015-03-06 | 2016-03-04 | Modified von willebrand factor having improved half-life |
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| IL319473A (en) | 2016-12-02 | 2025-05-01 | Bioverativ Therapeutics Inc | Methods for treating hemophilic arthritis using chimeric blood clotting factors |
| CA3069295A1 (en) | 2017-07-07 | 2019-01-10 | Baxalta Incorporated | Treatment of gastrointestinal bleeding in patients with severe von willebrand disease by administration of recombinant vwf |
| BR112020022164A2 (pt) | 2018-05-18 | 2021-02-02 | Bioverativ Therapeutics Inc. | métodos de tratamento de hemofilia a |
| US20220395560A1 (en) * | 2019-02-01 | 2022-12-15 | Takeda Pharmaceutical Company Limited | METHODS OF PROPHYLACTIC TREATMENT USING RECOMBINANT VWF (rVWF) |
| US12128090B2 (en) * | 2019-02-01 | 2024-10-29 | Takeda Pharmaceutical Company Limited | Methods of prophylactic treatment using recombinant VWF (rVWF) |
| CN114072420B (zh) * | 2019-07-04 | 2024-06-11 | 康诺贝林伦瑙有限公司 | 用于增加凝血因子viii的体外稳定性的截短的血管性血友病因子(vwf) |
| JP7680442B2 (ja) * | 2019-11-11 | 2025-05-20 | ツェー・エス・エル・ベーリング・レングナウ・アクチエンゲゼルシャフト | 第ｖｉｉｉ因子に対する寛容を誘導するためのポリペプチド |
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| US4444887A (en) | 1979-12-10 | 1984-04-24 | Sloan-Kettering Institute | Process for making human antibody producing B-lymphocytes |
| US4716111A (en) | 1982-08-11 | 1987-12-29 | Trustees Of Boston University | Process for producing human antibodies |
| GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
| US4970300A (en) | 1985-02-01 | 1990-11-13 | New York University | Modified factor VIII |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| GB8720833D0 (en) | 1987-09-04 | 1987-10-14 | Celltech Ltd | Recombinant dna product |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| GB8907617D0 (en) | 1989-04-05 | 1989-05-17 | Celltech Ltd | Drug delivery system |
| US5413923A (en) | 1989-07-25 | 1995-05-09 | Cell Genesys, Inc. | Homologous recombination for universal donor cells and chimeric mammalian hosts |
| GB8928874D0 (en) | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
| EP1690934A3 (en) | 1990-01-12 | 2008-07-30 | Abgenix, Inc. | Generation of xenogeneic antibodies |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
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-
2016
- 2016-03-04 ES ES16712738T patent/ES2772933T3/es active Active
- 2016-03-04 US US15/555,894 patent/US11155601B2/en active Active
- 2016-03-04 SG SG11201706659WA patent/SG11201706659WA/en unknown
- 2016-03-04 BR BR112017018468-0A patent/BR112017018468A2/pt not_active Application Discontinuation
- 2016-03-04 CN CN201680014025.4A patent/CN107406493B/zh active Active
- 2016-03-04 JP JP2017564946A patent/JP2018510212A/ja not_active Ceased
- 2016-03-04 KR KR1020177028206A patent/KR20170125941A/ko not_active Withdrawn
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- 2016-03-04 DK DK16712738.0T patent/DK3265483T3/da active
- 2016-03-04 WO PCT/EP2016/054647 patent/WO2016142288A1/en not_active Ceased
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| BR112017018468A2 (pt) | 2018-04-17 |
| JP2018510212A (ja) | 2018-04-12 |
| ES2772933T3 (es) | 2020-07-08 |
| AU2016231327B2 (en) | 2018-08-09 |
| EP3265483A1 (en) | 2018-01-10 |
| CN107406493B (zh) | 2021-08-13 |
| HK1244292A1 (en) | 2018-08-03 |
| US11155601B2 (en) | 2021-10-26 |
| US20180051067A1 (en) | 2018-02-22 |
| DK3265483T3 (da) | 2020-03-02 |
| AU2016231327A1 (en) | 2017-10-26 |
| EP3265483B1 (en) | 2019-12-11 |
| WO2016142288A1 (en) | 2016-09-15 |
| CN107406493A (zh) | 2017-11-28 |
| CA2978374A1 (en) | 2016-09-15 |
| SG11201706659WA (en) | 2017-09-28 |
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