SG11201706659WA - Modified von willebrand factor having improved half-life - Google Patents

Modified von willebrand factor having improved half-life

Info

Publication number
SG11201706659WA
SG11201706659WA SG11201706659WA SG11201706659WA SG11201706659WA SG 11201706659W A SG11201706659W A SG 11201706659WA SG 11201706659W A SG11201706659W A SG 11201706659WA SG 11201706659W A SG11201706659W A SG 11201706659WA SG 11201706659W A SG11201706659W A SG 11201706659WA
Authority
SG
Singapore
Prior art keywords
life
von willebrand
willebrand factor
improved half
modified von
Prior art date
Application number
SG11201706659WA
Other languages
English (en)
Inventor
Michael Moses
Stefan Schulte
Gerhard Dickneite
Uwe Kalina
Sabine Pestel
Thomas Weimer
Original Assignee
Csl Behring Recombinant Facility Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Csl Behring Recombinant Facility Ag filed Critical Csl Behring Recombinant Facility Ag
Publication of SG11201706659WA publication Critical patent/SG11201706659WA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SG11201706659WA 2015-03-06 2016-03-04 Modified von willebrand factor having improved half-life SG11201706659WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15158065 2015-03-06
PCT/EP2016/054647 WO2016142288A1 (en) 2015-03-06 2016-03-04 Modified von willebrand factor having improved half-life

Publications (1)

Publication Number Publication Date
SG11201706659WA true SG11201706659WA (en) 2017-09-28

Family

ID=52629450

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201706659WA SG11201706659WA (en) 2015-03-06 2016-03-04 Modified von willebrand factor having improved half-life

Country Status (12)

Country Link
US (1) US11155601B2 (https=)
EP (1) EP3265483B1 (https=)
JP (1) JP2018510212A (https=)
KR (1) KR20170125941A (https=)
CN (1) CN107406493B (https=)
AU (1) AU2016231327B2 (https=)
BR (1) BR112017018468A2 (https=)
CA (1) CA2978374A1 (https=)
DK (1) DK3265483T3 (https=)
ES (1) ES2772933T3 (https=)
SG (1) SG11201706659WA (https=)
WO (1) WO2016142288A1 (https=)

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US20220395560A1 (en) * 2019-02-01 2022-12-15 Takeda Pharmaceutical Company Limited METHODS OF PROPHYLACTIC TREATMENT USING RECOMBINANT VWF (rVWF)
WO2021001522A1 (en) * 2019-07-04 2021-01-07 CSL Behring Lengnau AG A truncated von willebrand factor (vwf) for increasing the in vitro stability of coagulation factor viii
US20220348637A1 (en) * 2019-11-11 2022-11-03 CSL Behring Lengnau AG Polypeptides for inducing tolerance to factor viii

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Also Published As

Publication number Publication date
JP2018510212A (ja) 2018-04-12
EP3265483A1 (en) 2018-01-10
AU2016231327B2 (en) 2018-08-09
KR20170125941A (ko) 2017-11-15
BR112017018468A2 (pt) 2018-04-17
EP3265483B1 (en) 2019-12-11
US11155601B2 (en) 2021-10-26
ES2772933T3 (es) 2020-07-08
CN107406493B (zh) 2021-08-13
DK3265483T3 (da) 2020-03-02
HK1244292A1 (en) 2018-08-03
CA2978374A1 (en) 2016-09-15
AU2016231327A1 (en) 2017-10-26
WO2016142288A1 (en) 2016-09-15
CN107406493A (zh) 2017-11-28
US20180051067A1 (en) 2018-02-22

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