KR20170124640A - 필라델피아 염색체-음성 골수증식 증후군의 관리를 위한 히스톤 디아세틸라아제 억제제의 용도 - Google Patents
필라델피아 염색체-음성 골수증식 증후군의 관리를 위한 히스톤 디아세틸라아제 억제제의 용도 Download PDFInfo
- Publication number
- KR20170124640A KR20170124640A KR1020177031565A KR20177031565A KR20170124640A KR 20170124640 A KR20170124640 A KR 20170124640A KR 1020177031565 A KR1020177031565 A KR 1020177031565A KR 20177031565 A KR20177031565 A KR 20177031565A KR 20170124640 A KR20170124640 A KR 20170124640A
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- South Korea
- Prior art keywords
- pharmaceutical composition
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- negative myeloproliferative
- myeloproliferative syndrome
- philadelphia
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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- A—HUMAN NECESSITIES
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- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Oncology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI2008A001720 | 2008-09-29 | ||
| ITMI2008A001720A IT1392908B1 (it) | 2008-09-29 | 2008-09-29 | Uso degli inibitori delle istone-deacetilasi per la cura di sindromi mieloproliferative philadelphia-negative |
| US19328308P | 2008-11-13 | 2008-11-13 | |
| US61/193,283 | 2008-11-13 | ||
| PCT/EP2009/062214 WO2010034693A1 (en) | 2008-09-29 | 2009-09-21 | Use of histone deacetylase inhibitors for the care of philadelphia-negative myeloproliferative syndromes |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020167020675A Division KR20160096721A (ko) | 2008-09-29 | 2009-09-21 | 필라델피아 염색체-음성 골수증식 증후군의 관리를 위한 히스톤 디아세틸라아제 억제제의 용도 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20170124640A true KR20170124640A (ko) | 2017-11-10 |
Family
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Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020177031565A Ceased KR20170124640A (ko) | 2008-09-29 | 2009-09-21 | 필라델피아 염색체-음성 골수증식 증후군의 관리를 위한 히스톤 디아세틸라아제 억제제의 용도 |
| KR1020117008487A Ceased KR20110069075A (ko) | 2008-09-29 | 2009-09-21 | 필라델피아 염색체-음성 골수증식 증후군의 관리를 위한 히스톤 디아세틸라아제 억제제의 용도 |
| KR1020167020675A Ceased KR20160096721A (ko) | 2008-09-29 | 2009-09-21 | 필라델피아 염색체-음성 골수증식 증후군의 관리를 위한 히스톤 디아세틸라아제 억제제의 용도 |
Family Applications After (2)
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| US8217079B2 (en) * | 2010-03-26 | 2012-07-10 | Italfarmaco Spa | Method for treating Philadelphia-negative myeloproliferative syndromes |
| WO2015165975A1 (en) * | 2014-04-29 | 2015-11-05 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and compositions for treating myeloid neoplasias |
| TW201821105A (zh) | 2016-10-20 | 2018-06-16 | 美商弗瑪治療公司 | 使用ｈｄａｃ１１抑制劑之方法 |
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| US11535607B2 (en) | 2018-04-20 | 2022-12-27 | Valo Health, Inc. | Isoindolines as HDAC inhibitors |
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| US6174905B1 (en) | 1996-09-30 | 2001-01-16 | Mitsui Chemicals, Inc. | Cell differentiation inducer |
| US8034831B2 (en) * | 2002-11-06 | 2011-10-11 | Celgene Corporation | Methods for the treatment and management of myeloproliferative diseases using 4-(amino)-2-(2,6-Dioxo(3-piperidyl)-isoindoline-1,3-dione in combination with other therapies |
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| US20080194681A1 (en) * | 2004-12-09 | 2008-08-14 | Kalypsys, Inc. | Novel Inhibitors of Histone Deacetylase for the Treatment of Disease |
| EP1910342A1 (en) * | 2005-07-29 | 2008-04-16 | Kalypsys, Inc. | Multicyclic sulfonamide compounds as inhibitors of histone deacetylase for the treatment of disease |
| CN101426903A (zh) | 2005-12-09 | 2009-05-06 | 麻省理工学院 | 基于细胞核形态鉴定并靶向肿瘤干细胞的方法 |
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| WO2008082646A2 (en) * | 2006-12-28 | 2008-07-10 | The Johns Hopkins University | Histone deacetylase inhibitors, combination therapies and methods of use |
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| US9522127B2 (en) | 2016-12-20 |
| EP2344253A1 (en) | 2011-07-20 |
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| CA2738081C (en) | 2017-11-07 |
| PL2344253T3 (pl) | 2014-09-30 |
| IT1392908B1 (it) | 2012-04-02 |
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| US20140039059A1 (en) | 2014-02-06 |
| CY1115255T1 (el) | 2017-01-04 |
| KR20160096721A (ko) | 2016-08-16 |
| BRPI0913699A2 (pt) | 2017-06-13 |
| DK2344253T3 (da) | 2014-06-16 |
| ITMI20081720A1 (it) | 2010-03-30 |
| EP2344253B1 (en) | 2014-04-23 |
| CN102164638A (zh) | 2011-08-24 |
| ES2478827T3 (es) | 2014-07-23 |
| US20110294892A1 (en) | 2011-12-01 |
| HRP20140499T1 (hr) | 2014-07-04 |
| SI2344253T1 (sl) | 2014-08-29 |
| US20210128512A1 (en) | 2021-05-06 |
| US20170049740A1 (en) | 2017-02-23 |
| SMT201400087B (it) | 2014-09-08 |
| WO2010034693A1 (en) | 2010-04-01 |
| KR20110069075A (ko) | 2011-06-22 |
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