KR20170122220A - 브루톤 타이로신 키나제 저해제의 약제학적 제제 - Google Patents

브루톤 타이로신 키나제 저해제의 약제학적 제제 Download PDF

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Publication number
KR20170122220A
KR20170122220A KR1020177026712A KR20177026712A KR20170122220A KR 20170122220 A KR20170122220 A KR 20170122220A KR 1020177026712 A KR1020177026712 A KR 1020177026712A KR 20177026712 A KR20177026712 A KR 20177026712A KR 20170122220 A KR20170122220 A KR 20170122220A
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South Korea
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amount
ibrutinib
lactose
excipient
microcrystalline cellulose
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Ceased
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KR1020177026712A
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English (en)
Korean (ko)
Inventor
하리샤 아틀러리
칭 와 총
로버트 쿠엘
헤오우 탄
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파마싸이클릭스 엘엘씨
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=56848552&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR20170122220(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 파마싸이클릭스 엘엘씨 filed Critical 파마싸이클릭스 엘엘씨
Priority to KR1020257002285A priority Critical patent/KR20250016514A/ko
Publication of KR20170122220A publication Critical patent/KR20170122220A/ko
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020177026712A 2015-03-03 2016-03-02 브루톤 타이로신 키나제 저해제의 약제학적 제제 Ceased KR20170122220A (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020257002285A KR20250016514A (ko) 2015-03-03 2016-03-02 브루톤 타이로신 키나제 저해제의 약제학적 제제

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562127717P 2015-03-03 2015-03-03
US62/127,717 2015-03-03
US201562193518P 2015-07-16 2015-07-16
US62/193,518 2015-07-16
PCT/US2016/020467 WO2016141068A1 (en) 2015-03-03 2016-03-02 Pharmaceutical formulations of bruton's tyrosine kinase inhibtor

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020257002285A Division KR20250016514A (ko) 2015-03-03 2016-03-02 브루톤 타이로신 키나제 저해제의 약제학적 제제

Publications (1)

Publication Number Publication Date
KR20170122220A true KR20170122220A (ko) 2017-11-03

Family

ID=56848552

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020177026712A Ceased KR20170122220A (ko) 2015-03-03 2016-03-02 브루톤 타이로신 키나제 저해제의 약제학적 제제
KR1020257002285A Pending KR20250016514A (ko) 2015-03-03 2016-03-02 브루톤 타이로신 키나제 저해제의 약제학적 제제

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020257002285A Pending KR20250016514A (ko) 2015-03-03 2016-03-02 브루톤 타이로신 키나제 저해제의 약제학적 제제

Country Status (28)

Country Link
US (9) US9655857B2 (https=)
EP (2) EP4338738A3 (https=)
JP (3) JP7149076B2 (https=)
KR (2) KR20170122220A (https=)
CN (4) CN121818554A (https=)
AU (4) AU2016226279B2 (https=)
BR (2) BR122023020985A2 (https=)
CA (3) CA3177995A1 (https=)
DK (1) DK3265084T3 (https=)
ES (1) ES2971597T3 (https=)
FI (1) FI3265084T3 (https=)
HR (1) HRP20240231T1 (https=)
HU (1) HUE065703T2 (https=)
IL (3) IL315294A (https=)
LT (1) LT3265084T (https=)
MD (1) MD3265084T2 (https=)
MX (5) MX394784B (https=)
NZ (1) NZ734446A (https=)
PL (1) PL3265084T3 (https=)
PT (1) PT3265084T (https=)
RS (1) RS65234B1 (https=)
RU (1) RU2017133990A (https=)
SG (2) SG11201707122QA (https=)
SI (1) SI3265084T1 (https=)
SM (1) SMT202400074T1 (https=)
TW (6) TWI810588B (https=)
WO (1) WO2016141068A1 (https=)
ZA (1) ZA201907661B (https=)

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CN104704129A (zh) 2012-07-24 2015-06-10 药品循环公司 与对布鲁顿酪氨酸激酶(btk)抑制剂的抗性相关的突变
JP2016538270A (ja) 2013-10-25 2016-12-08 ファーマサイクリックス エルエルシー 移植片対宿主病を処置し予防する方法
TW202228700A (zh) * 2013-12-02 2022-08-01 美商製藥公司 治療及預防異體抗體所驅動之慢性移植體對抗宿主疾病之方法
KR20170033358A (ko) * 2014-08-07 2017-03-24 파마싸이클릭스 엘엘씨 브루톤 티로신 키나아제 저해제의 신규한 제제
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BR112019011200B1 (pt) * 2016-12-01 2021-12-28 Arvinas Operations, Inc Derivados de tetrahidronaftaleno e tetrahidroisoquinolina como degradadores do receptor de estrogênio
CN108653231A (zh) * 2017-04-01 2018-10-16 北京赛林泰医药技术有限公司 含有布鲁顿酪氨酸激酶抑制剂的组合物及其制备方法
TWI843707B (zh) 2017-09-26 2024-06-01 美商提薩羅有限公司 尼拉帕尼（ｎｉｒａｐａｒｉｂ）調配物
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US20220175760A1 (en) * 2019-02-22 2022-06-09 Janssen Pharmaceutica Nv Pharmaceutical formulations
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US20170258729A1 (en) 2017-09-14
EP3265084A4 (en) 2018-08-01
CN121754493A (zh) 2026-03-31
NZ734446A (en) 2022-12-23
TW202315634A (zh) 2023-04-16
LT3265084T (lt) 2024-03-12
US12551448B2 (en) 2026-02-17
MX2021015405A (es) 2022-01-24
US20250228783A1 (en) 2025-07-17

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