KR20150139830A - 신경변성 및 기타 질환의 치료를 위한 조성물 및 방법 - Google Patents

신경변성 및 기타 질환의 치료를 위한 조성물 및 방법 Download PDF

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Publication number
KR20150139830A
KR20150139830A KR1020157023718A KR20157023718A KR20150139830A KR 20150139830 A KR20150139830 A KR 20150139830A KR 1020157023718 A KR1020157023718 A KR 1020157023718A KR 20157023718 A KR20157023718 A KR 20157023718A KR 20150139830 A KR20150139830 A KR 20150139830A
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KR
South Korea
Prior art keywords
sulfasalazine
pharmaceutical composition
patient
pharmaceutically acceptable
measured
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
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KR1020157023718A
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English (en)
Korean (ko)
Inventor
타데우스 크롬웰 리더
마크 웨이드 무어
더글라스 앨런 로렌츠
데이비드 키스 라이언
Original Assignee
글리아로직스 인코포레이티드
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Publication date
Application filed by 글리아로직스 인코포레이티드 filed Critical 글리아로직스 인코포레이티드
Publication of KR20150139830A publication Critical patent/KR20150139830A/ko
Withdrawn legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
KR1020157023718A 2013-02-01 2014-01-31 신경변성 및 기타 질환의 치료를 위한 조성물 및 방법 Withdrawn KR20150139830A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361759933P 2013-02-01 2013-02-01
US61/759,933 2013-02-01
US201361780340P 2013-03-13 2013-03-13
US61/780,340 2013-03-13
PCT/US2014/014290 WO2014121137A2 (en) 2013-02-01 2014-01-31 Compositions and methods for the treatment of neurodegenerative and other diseases

Publications (1)

Publication Number Publication Date
KR20150139830A true KR20150139830A (ko) 2015-12-14

Family

ID=50382538

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020157023718A Withdrawn KR20150139830A (ko) 2013-02-01 2014-01-31 신경변성 및 기타 질환의 치료를 위한 조성물 및 방법

Country Status (10)

Country Link
US (5) US9597339B2 (enExample)
EP (1) EP2950797B1 (enExample)
JP (2) JP6328146B2 (enExample)
KR (1) KR20150139830A (enExample)
CN (1) CN105163735B (enExample)
AU (2) AU2014212109B2 (enExample)
CA (1) CA2899032A1 (enExample)
ES (1) ES2752021T3 (enExample)
IL (1) IL240206A0 (enExample)
WO (1) WO2014121137A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9597339B2 (en) * 2013-02-01 2017-03-21 Glialogix, Inc. Compositions and methods for the treatment of neurodegenerative and other diseases
KR102364840B1 (ko) * 2014-11-05 2022-02-18 삼성전자주식회사 신경세포의 탈수초화와 연관된 질환을 치료하기 위한 약학적 조성물 및 그를 이용하는 방법
US20160199393A1 (en) * 2015-01-08 2016-07-14 China Medical University Methods of treating brain ischemia or hypoxia
ES2650175B1 (es) * 2016-04-15 2019-02-04 Servicio Andaluz De Salud Tratamiento de enfermedades neurodegenerativas
CN109414507A (zh) * 2016-04-26 2019-03-01 美国圣路易斯大学 用于预防和治疗神经退行性疾病的高度选择性腺苷a3受体亚型激动剂
US20180110760A1 (en) * 2016-10-21 2018-04-26 Glialogix, Inc. Compositions and methods for the treatmentof neurodegenerative and other diseases
US10473672B2 (en) * 2017-02-09 2019-11-12 Kaohsiung Chang Gung Memorial Hospital Methods for diagnosing and treating Alzheimers disease using G72 protein and SLC7A11 mRNA as biomarkers
US20230210871A1 (en) * 2017-10-12 2023-07-06 The Limited Company Research And Development Company "Medbiopharm" Use of sulfasalazine as an inhibitor of the formation of advanced glycation end products
JP6603815B2 (ja) * 2017-11-21 2019-11-06 積水化学工業株式会社 皮膚外用剤

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FR2608988B1 (fr) 1986-12-31 1991-01-11 Centre Nat Rech Scient Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanoparticules
HUT77373A (hu) 1994-09-29 1998-03-30 Andaris Limited Porlasztva szárított mikrorészecskék gyógyszerészeti hordozóként
US5874064A (en) 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
ITMI962356A1 (it) 1996-11-13 1998-05-13 Uni Degli Studi Di Brescia D I Uso di composti derivati da molecole ad attivita' antinfiammatoria di tipo non steroideo per la prevenzione e il trattamento di
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KR100417623B1 (ko) 2000-03-28 2004-02-05 주식회사 뉴로테크 뇌질환 예방 및 치료용 조성물
CA2307278A1 (en) 2000-04-28 2001-10-28 University Of British Columbia Use of n-heterocyclic substituted salicylic acids for inhibition of cellular uptake of cystine
WO2003063822A2 (en) 2002-02-01 2003-08-07 Pfizer Products Inc. Method for making homogeneous spray-dried solid amorphous drug dispersions utilizing modified spray-drying apparatus
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US20060045865A1 (en) 2004-08-27 2006-03-02 Spherics, Inc. Controlled regional oral delivery
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Also Published As

Publication number Publication date
JP2018123159A (ja) 2018-08-09
US20170079991A1 (en) 2017-03-23
CA2899032A1 (en) 2014-08-07
US9980978B2 (en) 2018-05-29
US20170165279A1 (en) 2017-06-15
CN105163735B (zh) 2018-12-11
WO2014121137A3 (en) 2014-11-27
JP2016507526A (ja) 2016-03-10
US10398713B2 (en) 2019-09-03
JP6328146B2 (ja) 2018-05-23
ES2752021T3 (es) 2020-04-02
EP2950797B1 (en) 2019-09-11
EP2950797A2 (en) 2015-12-09
AU2018222921A1 (en) 2018-09-20
US9918997B2 (en) 2018-03-20
AU2014212109B2 (en) 2018-05-31
US9974798B2 (en) 2018-05-22
US20140221321A1 (en) 2014-08-07
AU2014212109A1 (en) 2015-08-06
US9597339B2 (en) 2017-03-21
WO2014121137A2 (en) 2014-08-07
IL240206A0 (en) 2015-09-24
CN105163735A (zh) 2015-12-16
US20190015431A1 (en) 2019-01-17
US20170079990A1 (en) 2017-03-23

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Date Code Title Description
PA0105 International application

Patent event date: 20150831

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid