IL240206A0 - Preparations containing amorphous sulfasalazine and their uses - Google Patents

Preparations containing amorphous sulfasalazine and their uses

Info

Publication number
IL240206A0
IL240206A0 IL240206A IL24020615A IL240206A0 IL 240206 A0 IL240206 A0 IL 240206A0 IL 240206 A IL240206 A IL 240206A IL 24020615 A IL24020615 A IL 24020615A IL 240206 A0 IL240206 A0 IL 240206A0
Authority
IL
Israel
Prior art keywords
compositions
amorphous sulfasalazine
sulfasalazine
amorphous
Prior art date
Application number
IL240206A
Other languages
English (en)
Hebrew (he)
Original Assignee
Glialogix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glialogix Inc filed Critical Glialogix Inc
Publication of IL240206A0 publication Critical patent/IL240206A0/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/63Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
IL240206A 2013-02-01 2015-07-29 Preparations containing amorphous sulfasalazine and their uses IL240206A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361759933P 2013-02-01 2013-02-01
US201361780340P 2013-03-13 2013-03-13
PCT/US2014/014290 WO2014121137A2 (en) 2013-02-01 2014-01-31 Compositions and methods for the treatment of neurodegenerative and other diseases

Publications (1)

Publication Number Publication Date
IL240206A0 true IL240206A0 (en) 2015-09-24

Family

ID=50382538

Family Applications (1)

Application Number Title Priority Date Filing Date
IL240206A IL240206A0 (en) 2013-02-01 2015-07-29 Preparations containing amorphous sulfasalazine and their uses

Country Status (10)

Country Link
US (5) US9597339B2 (enExample)
EP (1) EP2950797B1 (enExample)
JP (2) JP6328146B2 (enExample)
KR (1) KR20150139830A (enExample)
CN (1) CN105163735B (enExample)
AU (2) AU2014212109B2 (enExample)
CA (1) CA2899032A1 (enExample)
ES (1) ES2752021T3 (enExample)
IL (1) IL240206A0 (enExample)
WO (1) WO2014121137A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2950797B1 (en) * 2013-02-01 2019-09-11 Glialogix, Inc. Compositions and methods for the treatment of neurodegenerative and other diseases
KR102364840B1 (ko) * 2014-11-05 2022-02-18 삼성전자주식회사 신경세포의 탈수초화와 연관된 질환을 치료하기 위한 약학적 조성물 및 그를 이용하는 방법
US20160199393A1 (en) * 2015-01-08 2016-07-14 China Medical University Methods of treating brain ischemia or hypoxia
ES2650175B1 (es) * 2016-04-15 2019-02-04 Servicio Andaluz De Salud Tratamiento de enfermedades neurodegenerativas
US20190343860A1 (en) * 2016-04-26 2019-11-14 Saint Louis University Highly selective adenosine a3 receptor subtype agonists for the prevention and treatment of neurodegenerative disorders
WO2018075865A1 (en) * 2016-10-21 2018-04-26 Glialogix, Inc. Compositions for the treatment of neurodegenerative diseases
US10473672B2 (en) * 2017-02-09 2019-11-12 Kaohsiung Chang Gung Memorial Hospital Methods for diagnosing and treating Alzheimers disease using G72 protein and SLC7A11 mRNA as biomarkers
RU2680844C1 (ru) * 2017-10-12 2019-02-28 федеральное государственное автономное образовательное учреждение высшего образования "Казанский (Приволжский) федеральный университет" (ФГАОУ ВО КФУ) Применение сульфасалазина в качестве ингибитора образования конечных продуктов гликирования
US11033506B2 (en) 2017-11-21 2021-06-15 Sekisui Chemical Co., Ltd. External skin preparation comprising a core-shell structure

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* Cited by examiner, † Cited by third party
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US2396145A (en) 1940-12-14 1946-03-05 Pharmscia Ab Heterocyclic sulphonamido azo compounds
FR2608988B1 (fr) 1986-12-31 1991-01-11 Centre Nat Rech Scient Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanoparticules
KR970705979A (ko) 1994-09-29 1997-11-03 디 히스 치료용 매개체로서의 분무-건조 미소입자 (Spray-dried microparticles as therapeutic vehicles)
US5874064A (en) 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
ITMI962356A1 (it) 1996-11-13 1998-05-13 Uni Degli Studi Di Brescia D I Uso di composti derivati da molecole ad attivita' antinfiammatoria di tipo non steroideo per la prevenzione e il trattamento di
ES2236832T3 (es) 1997-01-16 2005-07-16 Massachusetts Institute Of Technology Preparacion de particulas para inhalacion.
CA2336139C (en) 1998-06-24 2008-10-14 Advanced Inhalation Research, Inc. Large porous particles emitted from an inhaler
JP4416325B2 (ja) 1998-08-25 2010-02-17 アルカーメス,インコーポレイテッド 安定な噴霧乾燥タンパク質製剤
US6586008B1 (en) 1999-08-25 2003-07-01 Advanced Inhalation Research, Inc. Use of simple amino acids to form porous particles during spray drying
KR100417623B1 (ko) * 2000-03-28 2004-02-05 주식회사 뉴로테크 뇌질환 예방 및 치료용 조성물
CA2307278A1 (en) 2000-04-28 2001-10-28 University Of British Columbia Use of n-heterocyclic substituted salicylic acids for inhibition of cellular uptake of cystine
JP2005523260A (ja) 2002-02-01 2005-08-04 ファイザー・プロダクツ・インク 圧力ノズルを用いた均質噴霧乾燥固体非晶質薬剤分散体の製造方法
KR100664822B1 (ko) 2002-02-01 2007-01-04 화이자 프로덕츠 인코포레이티드 변형된 분무-건조 장치를 이용한 균질한 분무-건조된 고체비결정성 약물 분산액의 제조 방법
CL2004001884A1 (es) 2003-08-04 2005-06-03 Pfizer Prod Inc Procedimiento de secado por pulverizacion para la formacion de dispersiones solidas amorfas de un farmaco y polimeros.
US20060045865A1 (en) 2004-08-27 2006-03-02 Spherics, Inc. Controlled regional oral delivery
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US8034765B2 (en) 2005-08-31 2011-10-11 Abraxis Bioscience, Llc Compositions and methods for preparation of poorly water soluble drugs with increased stability
US20070053869A1 (en) 2005-09-02 2007-03-08 Yuichi Sugiyama Formulation and method for enhancement of gastrointestinal absorption of pharmaceutical agents
GB0602123D0 (en) * 2006-02-02 2006-03-15 Novartis Ag Organic compounds
PT1983984T (pt) 2006-02-02 2018-06-14 Novartis Ag Tratamento da esclerosa tuberosa
US7964585B2 (en) 2006-03-14 2011-06-21 Case Western Reserve University Composition and method of treating peripheral neuropathy
MX2009002166A (es) 2006-08-31 2009-03-12 Eurand Inc Sistema de distribucion de farmacos, que comprenden soluciones solidas de farmacos debilmente basicos.
US8309129B2 (en) 2007-05-03 2012-11-13 Bend Research, Inc. Nanoparticles comprising a drug, ethylcellulose, and a bile salt
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EP2259777A2 (en) * 2008-02-28 2010-12-15 BIAL - Portela & Ca., S.A. Pharmaceutical composition for poorly soluble drugs
DK2113254T3 (da) * 2008-04-28 2012-12-03 Txcell Sammensætninger til behandling af en inflammatorisk autoimmun sygdom
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WO2010111132A2 (en) 2009-03-27 2010-09-30 Bend Research, Inc. Spray-drying process
PT2611530T (pt) 2010-09-03 2019-05-09 Bend Res Inc Aparelho de secagem por pulverização e métodos de utilização do mesmo
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HK1204970A1 (en) 2012-01-31 2015-12-11 Cerulean Pharma Inc. Polymer-agent conjugates, particles, compositions, and related methods of use
EP2950797B1 (en) * 2013-02-01 2019-09-11 Glialogix, Inc. Compositions and methods for the treatment of neurodegenerative and other diseases
EP3089736B1 (en) 2013-12-31 2025-07-23 Ascendia Pharmaceuticals, LLC Pharmaceutical compositions for poorly water-soluble compounds

Also Published As

Publication number Publication date
JP2016507526A (ja) 2016-03-10
WO2014121137A3 (en) 2014-11-27
US9597339B2 (en) 2017-03-21
US9974798B2 (en) 2018-05-22
US20170079991A1 (en) 2017-03-23
JP2018123159A (ja) 2018-08-09
US20140221321A1 (en) 2014-08-07
CN105163735B (zh) 2018-12-11
ES2752021T3 (es) 2020-04-02
WO2014121137A2 (en) 2014-08-07
US10398713B2 (en) 2019-09-03
EP2950797A2 (en) 2015-12-09
US20170165279A1 (en) 2017-06-15
US9980978B2 (en) 2018-05-29
US9918997B2 (en) 2018-03-20
JP6328146B2 (ja) 2018-05-23
CN105163735A (zh) 2015-12-16
KR20150139830A (ko) 2015-12-14
CA2899032A1 (en) 2014-08-07
AU2018222921A1 (en) 2018-09-20
US20190015431A1 (en) 2019-01-17
EP2950797B1 (en) 2019-09-11
AU2014212109A1 (en) 2015-08-06
US20170079990A1 (en) 2017-03-23
AU2014212109B2 (en) 2018-05-31

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