KR20150132479A - 복합 유전자 세트에서의 독특하게 태그되고 재배열된 적응 면역 수용체 유전자 - Google Patents
복합 유전자 세트에서의 독특하게 태그되고 재배열된 적응 면역 수용체 유전자 Download PDFInfo
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- KR20150132479A KR20150132479A KR1020157029634A KR20157029634A KR20150132479A KR 20150132479 A KR20150132479 A KR 20150132479A KR 1020157029634 A KR1020157029634 A KR 1020157029634A KR 20157029634 A KR20157029634 A KR 20157029634A KR 20150132479 A KR20150132479 A KR 20150132479A
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- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
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- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1093—General methods of preparing gene libraries, not provided for in other subgroups
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- C12Q1/6846—Common amplification features
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
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- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/155—Modifications characterised by incorporating/generating a new priming site
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- C12Q2535/00—Reactions characterised by the assay type for determining the identity of a nucleotide base or a sequence of oligonucleotides
- C12Q2535/122—Massive parallel sequencing
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- C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
- C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
- C12Q2537/143—Multiplexing, i.e. use of multiple primers or probes in a single reaction, usually for simultaneously analyse of multiple analysis
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- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/179—Nucleic acid detection characterized by the use of physical, structural and functional properties the label being a nucleic acid
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- C—CHEMISTRY; METALLURGY
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
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- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361789408P | 2013-03-15 | 2013-03-15 | |
| US61/789,408 | 2013-03-15 | ||
| USPCT/US2013/045994 | 2013-06-14 | ||
| PCT/US2013/045994 WO2013188831A1 (en) | 2012-06-15 | 2013-06-14 | Uniquely tagged rearranged adaptive immune receptor genes in a complex gene set |
| PCT/US2014/030859 WO2014145992A1 (en) | 2013-03-15 | 2014-03-17 | Uniquely tagged rearranged adaptive immune receptor genes in a complex gene set |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20150132479A true KR20150132479A (ko) | 2015-11-25 |
Family
ID=51538155
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020157029634A Withdrawn KR20150132479A (ko) | 2013-03-15 | 2014-03-17 | 복합 유전자 세트에서의 독특하게 태그되고 재배열된 적응 면역 수용체 유전자 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20160024493A1 (enExample) |
| EP (1) | EP2971105B1 (enExample) |
| JP (1) | JP6431895B2 (enExample) |
| KR (1) | KR20150132479A (enExample) |
| CN (1) | CN105452483B (enExample) |
| AU (2) | AU2014232314B2 (enExample) |
| CA (1) | CA2906218A1 (enExample) |
| IL (1) | IL241394B (enExample) |
| SG (2) | SG11201506991VA (enExample) |
| WO (1) | WO2014145992A1 (enExample) |
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| JP6302847B2 (ja) | 2012-03-05 | 2018-03-28 | アダプティヴ バイオテクノロジーズ コーポレーション | 頻度が一致したサブユニットからの、対をなす免疫受容体鎖の決定 |
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| US10066265B2 (en) | 2014-04-01 | 2018-09-04 | Adaptive Biotechnologies Corp. | Determining antigen-specific t-cells |
| US11390921B2 (en) | 2014-04-01 | 2022-07-19 | Adaptive Biotechnologies Corporation | Determining WT-1 specific T cells and WT-1 specific T cell receptors (TCRs) |
| ES2777529T3 (es) | 2014-04-17 | 2020-08-05 | Adaptive Biotechnologies Corp | Cuantificación de genomas de células inmunitarias adaptativas en una mezcla compleja de células |
| US10202640B2 (en) * | 2014-05-07 | 2019-02-12 | The Board Of Trustees Of The Leland Stanford Junior University | Single cell analysis of T cells using high-throughput multiplex amplification and deep sequencing |
| EP3146079B1 (en) | 2014-05-22 | 2019-01-30 | The University Of British Columbia | Methods for determining lymphocyte receptor chain pairs |
| WO2016069886A1 (en) | 2014-10-29 | 2016-05-06 | Adaptive Biotechnologies Corporation | Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from many samples |
| US10246701B2 (en) | 2014-11-14 | 2019-04-02 | Adaptive Biotechnologies Corp. | Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture |
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| CN104562215B (zh) * | 2014-12-29 | 2017-03-22 | 北京诺禾致源科技股份有限公司 | 扩增子文库的构建方法 |
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- 2014-03-17 US US14/777,294 patent/US20160024493A1/en not_active Abandoned
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- 2014-03-17 EP EP14722474.5A patent/EP2971105B1/en active Active
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| WO2014145992A1 (en) | 2014-09-18 |
| SG11201506991VA (en) | 2015-10-29 |
| US20160024493A1 (en) | 2016-01-28 |
| CA2906218A1 (en) | 2014-09-18 |
| CN105452483A (zh) | 2016-03-30 |
| AU2020213348B2 (en) | 2022-05-19 |
| SG10201707394PA (en) | 2017-10-30 |
| IL241394A0 (en) | 2015-11-30 |
| JP6431895B2 (ja) | 2018-12-05 |
| JP2016512685A (ja) | 2016-05-09 |
| EP2971105B1 (en) | 2018-08-01 |
| CN105452483B (zh) | 2019-01-11 |
| AU2020213348A1 (en) | 2020-08-27 |
| AU2014232314A1 (en) | 2015-09-17 |
| EP2971105A1 (en) | 2016-01-20 |
| IL241394B (en) | 2019-12-31 |
| US20250043272A1 (en) | 2025-02-06 |
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