KR20150068404A - 우유로부터 락토페린을 정제하기 위한 개선된 방법 및 이의 제품 - Google Patents

우유로부터 락토페린을 정제하기 위한 개선된 방법 및 이의 제품 Download PDF

Info

Publication number
KR20150068404A
KR20150068404A KR1020157010356A KR20157010356A KR20150068404A KR 20150068404 A KR20150068404 A KR 20150068404A KR 1020157010356 A KR1020157010356 A KR 1020157010356A KR 20157010356 A KR20157010356 A KR 20157010356A KR 20150068404 A KR20150068404 A KR 20150068404A
Authority
KR
South Korea
Prior art keywords
lactoferrin
milk
treating
rnase
membrane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
KR1020157010356A
Other languages
English (en)
Korean (ko)
Inventor
앤드류 브라운
Original Assignee
머레이 걸번 코-어퍼러티브 컴퍼니 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2012904391A external-priority patent/AU2012904391A0/en
Application filed by 머레이 걸번 코-어퍼러티브 컴퍼니 리미티드 filed Critical 머레이 걸번 코-어퍼러티브 컴퍼니 리미티드
Publication of KR20150068404A publication Critical patent/KR20150068404A/ko
Abandoned legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/40—Transferrins, e.g. lactoferrins, ovotransferrins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
    • A23J1/20—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00—Working-up of proteins for foodstuffs
    • A23J3/04—Animal proteins
    • A23J3/08—Dairy proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Nutrition Science (AREA)
  • Water Supply & Treatment (AREA)
  • Analytical Chemistry (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
KR1020157010356A 2012-10-08 2013-10-08 우유로부터 락토페린을 정제하기 위한 개선된 방법 및 이의 제품 Abandoned KR20150068404A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
AU2012904391 2012-10-08
AU2012904391A AU2012904391A0 (en) 2012-10-08 Improved process for purifying milk proteins and products thereof
AU2013204858 2013-04-12
AU2013204858A AU2013204858B2 (en) 2012-10-08 2013-04-12 Improved process for purifying milk proteins and products thereof
PCT/AU2013/001152 WO2014056025A1 (en) 2012-10-08 2013-10-08 Improved process for purifying lactoferrin from milk and products thereof

Publications (1)

Publication Number Publication Date
KR20150068404A true KR20150068404A (ko) 2015-06-19

Family

ID=50476773

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020157010356A Abandoned KR20150068404A (ko) 2012-10-08 2013-10-08 우유로부터 락토페린을 정제하기 위한 개선된 방법 및 이의 제품

Country Status (12)

Country Link
US (1) US10016487B2 (enExample)
EP (1) EP2904006A4 (enExample)
JP (1) JP6475163B2 (enExample)
KR (1) KR20150068404A (enExample)
CN (1) CN104768971B (enExample)
AU (1) AU2013204858B2 (enExample)
BR (1) BR112015007674A2 (enExample)
CA (1) CA2886892A1 (enExample)
IN (1) IN2015DN02971A (enExample)
NZ (1) NZ631826A (enExample)
RU (1) RU2683228C2 (enExample)
WO (1) WO2014056025A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2013204858B2 (en) 2012-10-08 2015-06-25 Saputo Dairy Australia Pty Limited Improved process for purifying milk proteins and products thereof
CN106215174A (zh) * 2016-08-04 2016-12-14 无锡科捷诺生物科技有限责任公司 一种人乳铁蛋白的制剂化制备方法
CN112533494A (zh) 2018-06-22 2021-03-19 方塔拉合作集团有限公司 使用极性脂质治疗或预防妊娠期糖尿病
JP7370224B2 (ja) * 2019-11-08 2023-10-27 ライオン株式会社 ラクトフェリン含有腸溶製剤
FR3115037B1 (fr) * 2020-10-12 2025-02-21 Cie Laitiere Europeenne Procédé de purification de fraction de protéines cationiques et fraction ainsi obtenue
CN113278063A (zh) * 2021-05-13 2021-08-20 上海仁统生物科技中心 一种利用超滤法自初乳中获取乳铁蛋白的方法
IL311036A (en) * 2021-08-23 2024-04-01 Lactea Therapeutics Llc Lactoferrin compositions and methods of use
CN118355957A (zh) * 2023-01-19 2024-07-19 内蒙古伊利实业集团股份有限公司 提取乳铁蛋白的方法以及乳铁蛋白粉
PL248495B1 (pl) * 2023-05-07 2025-12-22 Polmlek Spolka Z Ograniczona Odpowiedzialnoscia Sposób uzyskiwania laktoferyny w proszku z surowego mleka

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2584727B1 (fr) * 1985-07-11 1988-06-17 Roussel Uclaf Procede d'extraction de proteines du lait, produits, application du procede, et compositions pharmaceutiques
US5221734A (en) 1987-10-01 1993-06-22 Ciba-Geigy Corporation Process for preparing a polypeptide growth factor for milk
GB8729031D0 (en) * 1987-12-11 1988-01-27 Express Foods Group Ltd Isolation of immunoglobulin rich fraction from whey
JP2686831B2 (ja) * 1989-09-22 1997-12-08 雪印乳業株式会社 鉄結合性蛋白質を分離、精製し、採取する方法
US5596082A (en) * 1992-01-15 1997-01-21 Campina Melkunie Bv Process for isolating lactoferrin and lactoperoxidase from milk and milk products, and products obtained by such process
JPH05202098A (ja) 1992-01-29 1993-08-10 Snow Brand Milk Prod Co Ltd 乳質原料から生理活性物質の製造法
US5756680A (en) * 1994-01-05 1998-05-26 Sepragen Corporation Sequential separation of whey proteins and formulations thereof
US5861491A (en) * 1994-02-16 1999-01-19 Pharming B.V. Isolation of lactoferrin from milk
NL1005677C2 (nl) * 1997-03-27 1998-09-29 Campina Melkunie Bv Werkwijze voor het winnen van groeifactoren, of een samenstelling die één of meer groeifactoren bevat, uit melk of een derivaat daarvan.
ATE420108T1 (de) * 2001-07-20 2009-01-15 Campina Bv Verfahren zur herstellung von preparationen aus milchprodukten, welche wachstumsfaktoren (tgf- beta und igf-1), lactoperoxidase und immunglobuline mit niedriger gegenseitiger verunreinigung enthalten
US6875459B2 (en) * 2001-09-10 2005-04-05 Henry B. Kopf Method and apparatus for separation of milk, colostrum, and whey
NZ535784A (en) * 2002-03-07 2006-02-24 Upfront Chromatography As A process of isolating lactoferrin
FR2841747B1 (fr) * 2002-07-02 2004-08-20 Cie Laitiere Europeenne Isolat de proteines de lait et procede pour sa preparation
GB0313892D0 (en) * 2003-06-16 2003-07-23 Hannah Res Inst Control of lactation
US20050208638A1 (en) * 2004-03-22 2005-09-22 Chao Wu Process for preparing bioactive protein-enriched whey products
EP1789073A4 (en) 2004-09-14 2011-06-08 Nexcell Biosciences Inc ISOLATION OF GROWTH AND DIFFERENTIATION FACTORS FROM COLOSTRUM
WO2007028211A1 (en) * 2005-09-09 2007-03-15 Murray Goulburn Co-Operative Co Limited Composition of whey growth factor extract for reducing muscle inflammation
FR2901796A1 (fr) * 2006-05-31 2007-12-07 Lab Francais Du Fractionnement Procede d'extraction d'une ou de plusieurs proteines presentes dans du lait
JP5276004B2 (ja) * 2006-11-10 2013-08-28 マリー ゴールバーン シーオー−オペレイティブ シーオー．リミテッド アンギオゲニンの調製方法
CA2723994C (en) * 2008-05-14 2018-05-01 Agriculture Victoria Services Pty Ltd Angiogenin-enriched milk fractions
WO2010112988A1 (en) 2009-01-28 2010-10-07 Jean-Paul Perraudin Method for production of lactoferrin
CN102413868B (zh) * 2009-04-23 2013-08-21 株式会社Jms 医疗用连接器
JPWO2012015037A1 (ja) 2010-07-30 2013-09-12 森永乳業株式会社 抗菌活性増強剤
AU2013204858B2 (en) * 2012-10-08 2015-06-25 Saputo Dairy Australia Pty Limited Improved process for purifying milk proteins and products thereof

Also Published As

Publication number Publication date
JP6475163B2 (ja) 2019-02-27
WO2014056025A8 (en) 2015-05-14
EP2904006A1 (en) 2015-08-12
IN2015DN02971A (enExample) 2015-09-18
AU2013204858B2 (en) 2015-06-25
CA2886892A1 (en) 2014-04-17
RU2683228C2 (ru) 2019-03-26
WO2014056025A1 (en) 2014-04-17
AU2013204858A1 (en) 2014-04-24
RU2015116933A (ru) 2016-11-27
US20150315264A1 (en) 2015-11-05
CN104768971A (zh) 2015-07-08
EP2904006A4 (en) 2016-04-06
US10016487B2 (en) 2018-07-10
CN104768971B (zh) 2017-12-05
JP2015536905A (ja) 2015-12-24
BR112015007674A2 (pt) 2017-07-04
NZ631826A (en) 2017-08-25

Similar Documents

Publication Publication Date Title
JP6475163B2 (ja) 乳汁からラクトフェリンを精製するための改良されたプロセスおよびその製品
EP2280999B1 (en) Process for producing milk fractions rich in secretory immunoglobulins
AU2009224095A1 (en) Process for isolating sialic acid containing oligosaccharides, and the compositions containing sialic acid containing oligosaccharides obtainable thereby
US20120245119A1 (en) Method for separating sialyllactose material
JP5641598B2 (ja) シアリルラクトース素材の分離方法
KR101404035B1 (ko) 신규 유 단백질 분획물 및 이의 만성 염증성 질환 예방또는 치료 용도
AU2013204850B2 (en) Improved process for purifying milk proteins and products thereof
US20130039903A1 (en) Eczema treatment
CN100480378C (zh) 生产乳过氧化物酶的方法
AU2011283472B2 (en) Antimicrobial activity enhancing agent
Mulvihill et al. Production of whey-protein-enriched products
AU2017231471B2 (en) Fractionation method for whey protein, production method for composition including alpha-lactalbumin, and production method for composition including beta-lactoglobulin
WO2013018169A1 (ja) 抗菌活性増強剤
JPH08301776A (ja) 上皮細胞の分化促進剤
HK1151046A (en) Process for producing milk fractions rich in secretory immunoglobulins
HK1151046B (en) Process for producing milk fractions rich in secretory immunoglobulins

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20150422

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20181005

Comment text: Request for Examination of Application

N231 Notification of change of applicant
PN2301 Change of applicant

Patent event date: 20181220

Comment text: Notification of Change of Applicant

Patent event code: PN23011R01D

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20190820

Patent event code: PE09021S01D

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

Patent event code: PE07011S01D

Comment text: Decision to Grant Registration

Patent event date: 20200203

NORF Unpaid initial registration fee
PC1904 Unpaid initial registration fee