CA2886892A1 - Improved process for purifying lactoferrin from milk and products thereof - Google Patents
Improved process for purifying lactoferrin from milk and products thereof Download PDFInfo
- Publication number
- CA2886892A1 CA2886892A1 CA2886892A CA2886892A CA2886892A1 CA 2886892 A1 CA2886892 A1 CA 2886892A1 CA 2886892 A CA2886892 A CA 2886892A CA 2886892 A CA2886892 A CA 2886892A CA 2886892 A1 CA2886892 A1 CA 2886892A1
- Authority
- CA
- Canada
- Prior art keywords
- lactoferrin
- milk
- salt
- treatment
- filtration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 235000013336 milk Nutrition 0.000 title claims abstract 17
- 239000008267 milk Substances 0.000 title claims abstract 17
- 210000004080 milk Anatomy 0.000 title claims abstract 17
- 102000010445 Lactoferrin Human genes 0.000 title claims abstract 16
- 108010063045 Lactoferrin Proteins 0.000 title claims abstract 16
- CSSYQJWUGATIHM-IKGCZBKSSA-N l-phenylalanyl-l-lysyl-l-cysteinyl-l-arginyl-l-arginyl-l-tryptophyl-l-glutaminyl-l-tryptophyl-l-arginyl-l-methionyl-l-lysyl-l-lysyl-l-leucylglycyl-l-alanyl-l-prolyl-l-seryl-l-isoleucyl-l-threonyl-l-cysteinyl-l-valyl-l-arginyl-l-arginyl-l-alanyl-l-phenylal Chemical compound C([C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C1=CC=CC=C1 CSSYQJWUGATIHM-IKGCZBKSSA-N 0.000 title claims abstract 16
- 235000021242 lactoferrin Nutrition 0.000 title claims abstract 16
- 229940078795 lactoferrin Drugs 0.000 title claims abstract 16
- 238000000034 method Methods 0.000 title claims abstract 14
- 238000001914 filtration Methods 0.000 claims abstract 11
- 150000003839 salts Chemical class 0.000 claims abstract 11
- 239000003102 growth factor Substances 0.000 claims abstract 10
- 239000012466 permeate Substances 0.000 claims abstract 8
- 239000012465 retentate Substances 0.000 claims abstract 4
- 206010028980 Neoplasm Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 201000011510 cancer Diseases 0.000 claims 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 230000036039 immunity Effects 0.000 claims 2
- 230000001737 promoting effect Effects 0.000 claims 2
- 206010000234 Abortion spontaneous Diseases 0.000 claims 1
- 208000009206 Abruptio Placentae Diseases 0.000 claims 1
- 201000001320 Atherosclerosis Diseases 0.000 claims 1
- 208000028564 B-cell non-Hodgkin lymphoma Diseases 0.000 claims 1
- 208000020084 Bone disease Diseases 0.000 claims 1
- 208000024172 Cardiovascular disease Diseases 0.000 claims 1
- 241000193403 Clostridium Species 0.000 claims 1
- 201000003883 Cystic fibrosis Diseases 0.000 claims 1
- 206010056340 Diabetic ulcer Diseases 0.000 claims 1
- 241000588724 Escherichia coli Species 0.000 claims 1
- 208000001951 Fetal Death Diseases 0.000 claims 1
- 208000001362 Fetal Growth Retardation Diseases 0.000 claims 1
- 206010055690 Foetal death Diseases 0.000 claims 1
- 208000009329 Graft vs Host Disease Diseases 0.000 claims 1
- 206010061218 Inflammation Diseases 0.000 claims 1
- 206010022971 Iron Deficiencies Diseases 0.000 claims 1
- 208000015710 Iron-Deficiency Anemia Diseases 0.000 claims 1
- 208000006816 Neonatal Sepsis Diseases 0.000 claims 1
- 206010048685 Oral infection Diseases 0.000 claims 1
- 206010036595 Premature delivery Diseases 0.000 claims 1
- 206010040070 Septic Shock Diseases 0.000 claims 1
- 241000194017 Streptococcus Species 0.000 claims 1
- 206010052779 Transplant rejections Diseases 0.000 claims 1
- 208000035868 Vascular inflammations Diseases 0.000 claims 1
- 206010052428 Wound Diseases 0.000 claims 1
- 208000027418 Wounds and injury Diseases 0.000 claims 1
- 208000007502 anemia Diseases 0.000 claims 1
- 230000001093 anti-cancer Effects 0.000 claims 1
- 239000002260 anti-inflammatory agent Substances 0.000 claims 1
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 1
- 230000000845 anti-microbial effect Effects 0.000 claims 1
- 230000000840 anti-viral effect Effects 0.000 claims 1
- 239000004599 antimicrobial Substances 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 239000003443 antiviral agent Substances 0.000 claims 1
- 230000032770 biofilm formation Effects 0.000 claims 1
- 235000012000 cholesterol Nutrition 0.000 claims 1
- 230000003247 decreasing effect Effects 0.000 claims 1
- 206010012601 diabetes mellitus Diseases 0.000 claims 1
- 230000023011 digestive tract development Effects 0.000 claims 1
- 208000035475 disorder Diseases 0.000 claims 1
- 231100000479 fetal death Toxicity 0.000 claims 1
- 230000001605 fetal effect Effects 0.000 claims 1
- 208000030941 fetal growth restriction Diseases 0.000 claims 1
- 208000004104 gestational diabetes Diseases 0.000 claims 1
- 208000024908 graft versus host disease Diseases 0.000 claims 1
- 230000012010 growth Effects 0.000 claims 1
- 230000003463 hyperproliferative effect Effects 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 208000037805 labour Diseases 0.000 claims 1
- 208000018773 low birth weight Diseases 0.000 claims 1
- 231100000533 low birth weight Toxicity 0.000 claims 1
- 230000008774 maternal effect Effects 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 238000005374 membrane filtration Methods 0.000 claims 1
- 230000000813 microbial effect Effects 0.000 claims 1
- 208000015994 miscarriage Diseases 0.000 claims 1
- 230000001537 neural effect Effects 0.000 claims 1
- 210000000056 organ Anatomy 0.000 claims 1
- 230000011164 ossification Effects 0.000 claims 1
- 201000008482 osteoarthritis Diseases 0.000 claims 1
- 201000001245 periodontitis Diseases 0.000 claims 1
- 201000008532 placental abruption Diseases 0.000 claims 1
- 201000011461 pre-eclampsia Diseases 0.000 claims 1
- 230000035935 pregnancy Effects 0.000 claims 1
- 230000002028 premature Effects 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 230000002062 proliferating effect Effects 0.000 claims 1
- 239000000718 radiation-protective agent Substances 0.000 claims 1
- 208000023504 respiratory system disease Diseases 0.000 claims 1
- 230000036303 septic shock Effects 0.000 claims 1
- 210000004927 skin cell Anatomy 0.000 claims 1
- 208000000995 spontaneous abortion Diseases 0.000 claims 1
- 230000009885 systemic effect Effects 0.000 claims 1
- 208000019206 urinary tract infection Diseases 0.000 claims 1
- 230000003612 virological effect Effects 0.000 claims 1
- 230000029663 wound healing Effects 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/40—Transferrins, e.g. lactoferrins, ovotransferrins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
- A23J1/20—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Diabetes (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Nutrition Science (AREA)
- Water Supply & Treatment (AREA)
- Analytical Chemistry (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2012904391 | 2012-10-08 | ||
| AU2012904391A AU2012904391A0 (en) | 2012-10-08 | Improved process for purifying milk proteins and products thereof | |
| AU2013204858 | 2013-04-12 | ||
| AU2013204858A AU2013204858B2 (en) | 2012-10-08 | 2013-04-12 | Improved process for purifying milk proteins and products thereof |
| PCT/AU2013/001152 WO2014056025A1 (en) | 2012-10-08 | 2013-10-08 | Improved process for purifying lactoferrin from milk and products thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2886892A1 true CA2886892A1 (en) | 2014-04-17 |
Family
ID=50476773
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2886892A Abandoned CA2886892A1 (en) | 2012-10-08 | 2013-10-08 | Improved process for purifying lactoferrin from milk and products thereof |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10016487B2 (enExample) |
| EP (1) | EP2904006A4 (enExample) |
| JP (1) | JP6475163B2 (enExample) |
| KR (1) | KR20150068404A (enExample) |
| CN (1) | CN104768971B (enExample) |
| AU (1) | AU2013204858B2 (enExample) |
| BR (1) | BR112015007674A2 (enExample) |
| CA (1) | CA2886892A1 (enExample) |
| IN (1) | IN2015DN02971A (enExample) |
| NZ (1) | NZ631826A (enExample) |
| RU (1) | RU2683228C2 (enExample) |
| WO (1) | WO2014056025A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4392446A4 (en) * | 2021-08-23 | 2025-07-16 | Lactea Therapeutics Llc | LACTOFERRIN COMPOSITIONS AND METHODS OF USE |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2013204858B2 (en) | 2012-10-08 | 2015-06-25 | Saputo Dairy Australia Pty Limited | Improved process for purifying milk proteins and products thereof |
| CN106215174A (zh) * | 2016-08-04 | 2016-12-14 | 无锡科捷诺生物科技有限责任公司 | 一种人乳铁蛋白的制剂化制备方法 |
| CN112533494A (zh) | 2018-06-22 | 2021-03-19 | 方塔拉合作集团有限公司 | 使用极性脂质治疗或预防妊娠期糖尿病 |
| JP7370224B2 (ja) * | 2019-11-08 | 2023-10-27 | ライオン株式会社 | ラクトフェリン含有腸溶製剤 |
| FR3115037B1 (fr) * | 2020-10-12 | 2025-02-21 | Cie Laitiere Europeenne | Procédé de purification de fraction de protéines cationiques et fraction ainsi obtenue |
| CN113278063A (zh) * | 2021-05-13 | 2021-08-20 | 上海仁统生物科技中心 | 一种利用超滤法自初乳中获取乳铁蛋白的方法 |
| CN118355957A (zh) * | 2023-01-19 | 2024-07-19 | 内蒙古伊利实业集团股份有限公司 | 提取乳铁蛋白的方法以及乳铁蛋白粉 |
| PL248495B1 (pl) * | 2023-05-07 | 2025-12-22 | Polmlek Spolka Z Ograniczona Odpowiedzialnoscia | Sposób uzyskiwania laktoferyny w proszku z surowego mleka |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2584727B1 (fr) * | 1985-07-11 | 1988-06-17 | Roussel Uclaf | Procede d'extraction de proteines du lait, produits, application du procede, et compositions pharmaceutiques |
| US5221734A (en) | 1987-10-01 | 1993-06-22 | Ciba-Geigy Corporation | Process for preparing a polypeptide growth factor for milk |
| GB8729031D0 (en) * | 1987-12-11 | 1988-01-27 | Express Foods Group Ltd | Isolation of immunoglobulin rich fraction from whey |
| JP2686831B2 (ja) * | 1989-09-22 | 1997-12-08 | 雪印乳業株式会社 | 鉄結合性蛋白質を分離、精製し、採取する方法 |
| US5596082A (en) * | 1992-01-15 | 1997-01-21 | Campina Melkunie Bv | Process for isolating lactoferrin and lactoperoxidase from milk and milk products, and products obtained by such process |
| JPH05202098A (ja) | 1992-01-29 | 1993-08-10 | Snow Brand Milk Prod Co Ltd | 乳質原料から生理活性物質の製造法 |
| US5756680A (en) * | 1994-01-05 | 1998-05-26 | Sepragen Corporation | Sequential separation of whey proteins and formulations thereof |
| US5861491A (en) * | 1994-02-16 | 1999-01-19 | Pharming B.V. | Isolation of lactoferrin from milk |
| NL1005677C2 (nl) * | 1997-03-27 | 1998-09-29 | Campina Melkunie Bv | Werkwijze voor het winnen van groeifactoren, of een samenstelling die één of meer groeifactoren bevat, uit melk of een derivaat daarvan. |
| ATE420108T1 (de) * | 2001-07-20 | 2009-01-15 | Campina Bv | Verfahren zur herstellung von preparationen aus milchprodukten, welche wachstumsfaktoren (tgf- beta und igf-1), lactoperoxidase und immunglobuline mit niedriger gegenseitiger verunreinigung enthalten |
| US6875459B2 (en) * | 2001-09-10 | 2005-04-05 | Henry B. Kopf | Method and apparatus for separation of milk, colostrum, and whey |
| NZ535784A (en) * | 2002-03-07 | 2006-02-24 | Upfront Chromatography As | A process of isolating lactoferrin |
| FR2841747B1 (fr) * | 2002-07-02 | 2004-08-20 | Cie Laitiere Europeenne | Isolat de proteines de lait et procede pour sa preparation |
| GB0313892D0 (en) * | 2003-06-16 | 2003-07-23 | Hannah Res Inst | Control of lactation |
| US20050208638A1 (en) * | 2004-03-22 | 2005-09-22 | Chao Wu | Process for preparing bioactive protein-enriched whey products |
| EP1789073A4 (en) | 2004-09-14 | 2011-06-08 | Nexcell Biosciences Inc | ISOLATION OF GROWTH AND DIFFERENTIATION FACTORS FROM COLOSTRUM |
| WO2007028211A1 (en) * | 2005-09-09 | 2007-03-15 | Murray Goulburn Co-Operative Co Limited | Composition of whey growth factor extract for reducing muscle inflammation |
| FR2901796A1 (fr) * | 2006-05-31 | 2007-12-07 | Lab Francais Du Fractionnement | Procede d'extraction d'une ou de plusieurs proteines presentes dans du lait |
| JP5276004B2 (ja) * | 2006-11-10 | 2013-08-28 | マリー ゴールバーン シーオー−オペレイティブ シーオー．リミテッド | アンギオゲニンの調製方法 |
| CA2723994C (en) * | 2008-05-14 | 2018-05-01 | Agriculture Victoria Services Pty Ltd | Angiogenin-enriched milk fractions |
| WO2010112988A1 (en) | 2009-01-28 | 2010-10-07 | Jean-Paul Perraudin | Method for production of lactoferrin |
| CN102413868B (zh) * | 2009-04-23 | 2013-08-21 | 株式会社Jms | 医疗用连接器 |
| JPWO2012015037A1 (ja) | 2010-07-30 | 2013-09-12 | 森永乳業株式会社 | 抗菌活性増強剤 |
| AU2013204858B2 (en) * | 2012-10-08 | 2015-06-25 | Saputo Dairy Australia Pty Limited | Improved process for purifying milk proteins and products thereof |
-
2013
- 2013-04-12 AU AU2013204858A patent/AU2013204858B2/en active Active
- 2013-10-08 WO PCT/AU2013/001152 patent/WO2014056025A1/en not_active Ceased
- 2013-10-08 US US14/434,324 patent/US10016487B2/en active Active
- 2013-10-08 JP JP2015534883A patent/JP6475163B2/ja not_active Expired - Fee Related
- 2013-10-08 EP EP13844731.3A patent/EP2904006A4/en not_active Withdrawn
- 2013-10-08 IN IN2971DEN2015 patent/IN2015DN02971A/en unknown
- 2013-10-08 CA CA2886892A patent/CA2886892A1/en not_active Abandoned
- 2013-10-08 RU RU2015116933A patent/RU2683228C2/ru not_active IP Right Cessation
- 2013-10-08 NZ NZ631826A patent/NZ631826A/en not_active IP Right Cessation
- 2013-10-08 BR BR112015007674A patent/BR112015007674A2/pt not_active Application Discontinuation
- 2013-10-08 KR KR1020157010356A patent/KR20150068404A/ko not_active Abandoned
- 2013-10-08 CN CN201380055328.7A patent/CN104768971B/zh not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4392446A4 (en) * | 2021-08-23 | 2025-07-16 | Lactea Therapeutics Llc | LACTOFERRIN COMPOSITIONS AND METHODS OF USE |
Also Published As
| Publication number | Publication date |
|---|---|
| JP6475163B2 (ja) | 2019-02-27 |
| WO2014056025A8 (en) | 2015-05-14 |
| EP2904006A1 (en) | 2015-08-12 |
| IN2015DN02971A (enExample) | 2015-09-18 |
| AU2013204858B2 (en) | 2015-06-25 |
| KR20150068404A (ko) | 2015-06-19 |
| RU2683228C2 (ru) | 2019-03-26 |
| WO2014056025A1 (en) | 2014-04-17 |
| AU2013204858A1 (en) | 2014-04-24 |
| RU2015116933A (ru) | 2016-11-27 |
| US20150315264A1 (en) | 2015-11-05 |
| CN104768971A (zh) | 2015-07-08 |
| EP2904006A4 (en) | 2016-04-06 |
| US10016487B2 (en) | 2018-07-10 |
| CN104768971B (zh) | 2017-12-05 |
| JP2015536905A (ja) | 2015-12-24 |
| BR112015007674A2 (pt) | 2017-07-04 |
| NZ631826A (en) | 2017-08-25 |
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| EEER | Examination request |
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| FZDE | Discontinued |
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