AU2013204858B2 - Improved process for purifying milk proteins and products thereof - Google Patents

Improved process for purifying milk proteins and products thereof Download PDF

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Publication number
AU2013204858B2
AU2013204858B2 AU2013204858A AU2013204858A AU2013204858B2 AU 2013204858 B2 AU2013204858 B2 AU 2013204858B2 AU 2013204858 A AU2013204858 A AU 2013204858A AU 2013204858 A AU2013204858 A AU 2013204858A AU 2013204858 B2 AU2013204858 B2 AU 2013204858B2
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AU
Australia
Prior art keywords
lactoferrin
milk
salt
treatment
filtration
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Active
Application number
AU2013204858A
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English (en)
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AU2013204858A1 (en
Inventor
Andrew Brown
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Saputo Dairy Australia Pty Ltd Canada
Original Assignee
Saputo Dairy Australia Pty Ltd Canada
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2012904391A external-priority patent/AU2012904391A0/en
Application filed by Saputo Dairy Australia Pty Ltd Canada filed Critical Saputo Dairy Australia Pty Ltd Canada
Priority to AU2013204858A priority Critical patent/AU2013204858B2/en
Priority to JP2015534883A priority patent/JP6475163B2/ja
Priority to US14/434,324 priority patent/US10016487B2/en
Priority to BR112015007674A priority patent/BR112015007674A2/pt
Priority to CN201380055328.7A priority patent/CN104768971B/zh
Priority to RU2015116933A priority patent/RU2683228C2/ru
Priority to NZ631826A priority patent/NZ631826A/en
Priority to EP13844731.3A priority patent/EP2904006A4/en
Priority to KR1020157010356A priority patent/KR20150068404A/ko
Priority to IN2971DEN2015 priority patent/IN2015DN02971A/en
Priority to PCT/AU2013/001152 priority patent/WO2014056025A1/en
Priority to CA2886892A priority patent/CA2886892A1/en
Publication of AU2013204858A1 publication Critical patent/AU2013204858A1/en
Publication of AU2013204858B2 publication Critical patent/AU2013204858B2/en
Application granted granted Critical
Assigned to Saputo Dairy Australia Pty Limited reassignment Saputo Dairy Australia Pty Limited Request for Assignment Assignors: MURRAY GOULBURN CO-OPERATIVE CO. LIMITED
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/40—Transferrins, e.g. lactoferrins, ovotransferrins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
    • A23J1/20—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Nutrition Science (AREA)
  • Water Supply & Treatment (AREA)
  • Analytical Chemistry (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
AU2013204858A 2012-10-08 2013-04-12 Improved process for purifying milk proteins and products thereof Active AU2013204858B2 (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
AU2013204858A AU2013204858B2 (en) 2012-10-08 2013-04-12 Improved process for purifying milk proteins and products thereof
KR1020157010356A KR20150068404A (ko) 2012-10-08 2013-10-08 우유로부터 락토페린을 정제하기 위한 개선된 방법 및 이의 제품
PCT/AU2013/001152 WO2014056025A1 (en) 2012-10-08 2013-10-08 Improved process for purifying lactoferrin from milk and products thereof
BR112015007674A BR112015007674A2 (pt) 2012-10-08 2013-10-08 processo aperfeiçoado para purificar lactoferrina de leite e produtos do mesmo
CN201380055328.7A CN104768971B (zh) 2012-10-08 2013-10-08 用于从乳纯化乳铁蛋白的改进方法及其产品
RU2015116933A RU2683228C2 (ru) 2012-10-08 2013-10-08 Усовершенствованный способ очистки лактоферрина молока и его продукты
NZ631826A NZ631826A (en) 2012-10-08 2013-10-08 Improved process for purifying lactoferrin from milk and products thereof
EP13844731.3A EP2904006A4 (en) 2012-10-08 2013-10-08 IMPROVED PROCESS FOR THE PURIFICATION OF LACTOFERRIN FROM MILK AND PRODUCTS THEREOF
JP2015534883A JP6475163B2 (ja) 2012-10-08 2013-10-08 乳汁からラクトフェリンを精製するための改良されたプロセスおよびその製品
IN2971DEN2015 IN2015DN02971A (enExample) 2012-10-08 2013-10-08
US14/434,324 US10016487B2 (en) 2012-10-08 2013-10-08 Process for purifying lactoferrin from milk and products thereof
CA2886892A CA2886892A1 (en) 2012-10-08 2013-10-08 Improved process for purifying lactoferrin from milk and products thereof

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2012904391 2012-10-08
AU2012904391A AU2012904391A0 (en) 2012-10-08 Improved process for purifying milk proteins and products thereof
AU2013204858A AU2013204858B2 (en) 2012-10-08 2013-04-12 Improved process for purifying milk proteins and products thereof

Publications (2)

Publication Number Publication Date
AU2013204858A1 AU2013204858A1 (en) 2014-04-24
AU2013204858B2 true AU2013204858B2 (en) 2015-06-25

Family

ID=50476773

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2013204858A Active AU2013204858B2 (en) 2012-10-08 2013-04-12 Improved process for purifying milk proteins and products thereof

Country Status (12)

Country Link
US (1) US10016487B2 (enExample)
EP (1) EP2904006A4 (enExample)
JP (1) JP6475163B2 (enExample)
KR (1) KR20150068404A (enExample)
CN (1) CN104768971B (enExample)
AU (1) AU2013204858B2 (enExample)
BR (1) BR112015007674A2 (enExample)
CA (1) CA2886892A1 (enExample)
IN (1) IN2015DN02971A (enExample)
NZ (1) NZ631826A (enExample)
RU (1) RU2683228C2 (enExample)
WO (1) WO2014056025A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2013204858B2 (en) 2012-10-08 2015-06-25 Saputo Dairy Australia Pty Limited Improved process for purifying milk proteins and products thereof
CN106215174A (zh) * 2016-08-04 2016-12-14 无锡科捷诺生物科技有限责任公司 一种人乳铁蛋白的制剂化制备方法
CN112533494A (zh) 2018-06-22 2021-03-19 方塔拉合作集团有限公司 使用极性脂质治疗或预防妊娠期糖尿病
JP7370224B2 (ja) * 2019-11-08 2023-10-27 ライオン株式会社 ラクトフェリン含有腸溶製剤
FR3115037B1 (fr) * 2020-10-12 2025-02-21 Cie Laitiere Europeenne Procédé de purification de fraction de protéines cationiques et fraction ainsi obtenue
CN113278063A (zh) * 2021-05-13 2021-08-20 上海仁统生物科技中心 一种利用超滤法自初乳中获取乳铁蛋白的方法
IL311036A (en) * 2021-08-23 2024-04-01 Lactea Therapeutics Llc Lactoferrin compositions and methods of use
CN118355957A (zh) * 2023-01-19 2024-07-19 内蒙古伊利实业集团股份有限公司 提取乳铁蛋白的方法以及乳铁蛋白粉
PL248495B1 (pl) * 2023-05-07 2025-12-22 Polmlek Spolka Z Ograniczona Odpowiedzialnoscia Sposób uzyskiwania laktoferyny w proszku z surowego mleka

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993013676A1 (en) * 1992-01-15 1993-07-22 Campina Melkunie B.V. Process for isolating lactoferrin and lactoperoxidase from milk and milk products, and products obtained by such process
WO1995022258A2 (en) * 1994-02-16 1995-08-24 Pharming Bv Isolation of lactoferrin from milk
WO2003008447A1 (en) * 2001-07-20 2003-01-30 Campina B.V. Process for obtaining growth factor (tgf-beta and igf-1), lactoperoxidase and immunoglobulins preparations from milk products having low mutual cross-contamination
WO2003073866A1 (en) * 2002-03-07 2003-09-12 Upfront Chromatography A/S A process of isolating lactoferrin
US20050208638A1 (en) * 2004-03-22 2005-09-22 Chao Wu Process for preparing bioactive protein-enriched whey products
US20060040025A1 (en) * 2002-07-02 2006-02-23 Jerome Souppe Milk protein isolate and method for preparing same

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US5221734A (en) 1987-10-01 1993-06-22 Ciba-Geigy Corporation Process for preparing a polypeptide growth factor for milk
GB8729031D0 (en) * 1987-12-11 1988-01-27 Express Foods Group Ltd Isolation of immunoglobulin rich fraction from whey
JP2686831B2 (ja) * 1989-09-22 1997-12-08 雪印乳業株式会社 鉄結合性蛋白質を分離、精製し、採取する方法
JPH05202098A (ja) 1992-01-29 1993-08-10 Snow Brand Milk Prod Co Ltd 乳質原料から生理活性物質の製造法
US5756680A (en) * 1994-01-05 1998-05-26 Sepragen Corporation Sequential separation of whey proteins and formulations thereof
NL1005677C2 (nl) * 1997-03-27 1998-09-29 Campina Melkunie Bv Werkwijze voor het winnen van groeifactoren, of een samenstelling die één of meer groeifactoren bevat, uit melk of een derivaat daarvan.
US6875459B2 (en) * 2001-09-10 2005-04-05 Henry B. Kopf Method and apparatus for separation of milk, colostrum, and whey
GB0313892D0 (en) * 2003-06-16 2003-07-23 Hannah Res Inst Control of lactation
EP1789073A4 (en) 2004-09-14 2011-06-08 Nexcell Biosciences Inc ISOLATION OF GROWTH AND DIFFERENTIATION FACTORS FROM COLOSTRUM
WO2007028211A1 (en) * 2005-09-09 2007-03-15 Murray Goulburn Co-Operative Co Limited Composition of whey growth factor extract for reducing muscle inflammation
FR2901796A1 (fr) * 2006-05-31 2007-12-07 Lab Francais Du Fractionnement Procede d'extraction d'une ou de plusieurs proteines presentes dans du lait
JP5276004B2 (ja) * 2006-11-10 2013-08-28 マリー ゴールバーン シーオー−オペレイティブ シーオー．リミテッド アンギオゲニンの調製方法
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WO2010112988A1 (en) 2009-01-28 2010-10-07 Jean-Paul Perraudin Method for production of lactoferrin
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JPWO2012015037A1 (ja) 2010-07-30 2013-09-12 森永乳業株式会社 抗菌活性増強剤
AU2013204858B2 (en) * 2012-10-08 2015-06-25 Saputo Dairy Australia Pty Limited Improved process for purifying milk proteins and products thereof

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993013676A1 (en) * 1992-01-15 1993-07-22 Campina Melkunie B.V. Process for isolating lactoferrin and lactoperoxidase from milk and milk products, and products obtained by such process
WO1995022258A2 (en) * 1994-02-16 1995-08-24 Pharming Bv Isolation of lactoferrin from milk
WO2003008447A1 (en) * 2001-07-20 2003-01-30 Campina B.V. Process for obtaining growth factor (tgf-beta and igf-1), lactoperoxidase and immunoglobulins preparations from milk products having low mutual cross-contamination
WO2003073866A1 (en) * 2002-03-07 2003-09-12 Upfront Chromatography A/S A process of isolating lactoferrin
US20060040025A1 (en) * 2002-07-02 2006-02-23 Jerome Souppe Milk protein isolate and method for preparing same
US20050208638A1 (en) * 2004-03-22 2005-09-22 Chao Wu Process for preparing bioactive protein-enriched whey products

Also Published As

Publication number Publication date
JP6475163B2 (ja) 2019-02-27
WO2014056025A8 (en) 2015-05-14
EP2904006A1 (en) 2015-08-12
IN2015DN02971A (enExample) 2015-09-18
CA2886892A1 (en) 2014-04-17
KR20150068404A (ko) 2015-06-19
RU2683228C2 (ru) 2019-03-26
WO2014056025A1 (en) 2014-04-17
AU2013204858A1 (en) 2014-04-24
RU2015116933A (ru) 2016-11-27
US20150315264A1 (en) 2015-11-05
CN104768971A (zh) 2015-07-08
EP2904006A4 (en) 2016-04-06
US10016487B2 (en) 2018-07-10
CN104768971B (zh) 2017-12-05
JP2015536905A (ja) 2015-12-24
BR112015007674A2 (pt) 2017-07-04
NZ631826A (en) 2017-08-25

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