KR20150031897A - Perfume composition for expressing the fragrance of juniperus rigida - Google Patents

Abstract

The present invention relates to a perfume composition for reproducing fragrance of Juniperus rigida and to skin externals comprising the perfume composition. The perfume composition according to the present invention can be applied to cosmetic products (perfume, cosmetics, body lotion, and the likes) utilizing effects of the Juniperus rigida.

Description

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a perfume composition that reproduces fragrance of juniper tree.

The present invention relates to a perfume composition recreating the fragrance of Pinaceae juniper tree and a composition for external application for skin comprising the perfume composition.

Junjoo is a species distributed in Korea, Japan, China and so on. It grows well in the foothills of the foot, especially in limestone areas. It is about 8m in height and 20cm in diameter. Leaves are narrow in line, three in number, with pointed ends and narrow white grooves in the center of the outer surface. Leaf length is 12 ~ 20mm. The flower blooms in May, and the greenish brown flower hangs on the axilla of the old branch. A male flower has 1 to 3 blooms, 20 scales, and 4 ~ 5 anthers. The female flower is bloomed one by one, it is round, there are nine pieces of fruit, three are deep, and there are three undergrowths in it.

Korean Patent Publication No. KR 2012-0051456 relates to a perfume composition recreating an oriental herb scent. The patent discloses the use of juniper fruit which is known to have a medicinal effect in order to reproduce herbal scent as a constitution of the invention. However, the fragrance of the juniper tree itself is not well known, and a perfume composition for reproducing the fragrance of the juniper tree has not been developed to date.

Korea Patent No. KR-2012-0051456

It is an object of the present invention to provide a fragrance composition recreating the fragrance of juniper tree containing juniper fruit extract as an active ingredient.

Another object of the present invention is to provide a composition for external application for skin comprising the perfume composition.

The present invention relates to a perfume composition recreating the fragrance of juniper tree containing Juniperus japonica extract as an active ingredient.

The present invention also relates to a composition for external application for skin comprising a fragrance composition recreating the fragrance of juniper tree.

INDUSTRIAL APPLICABILITY The present invention can provide a fragrance composition that can reproduce the original fragrance of juniper tree and exhibits excellent palatability and aroma effect. The perfume composition according to the present invention can be applied to related fragrance products (fragrance, cosmetics, body lotion, etc.) utilizing the efficacy of juniper.

Figure 1 relates to 10-20 International Standard Electrode Assembly.
FIG. 2 shows an example of brain wave changes before and after inhalation using the EEG brain mapping (3D brain mapping program).
FIG. 3 is a brain map showing Absolute beta changes before and after inhalation of the Juniper stem extract.
Figure 4 is a brain map showing relative beta changes before and after inhalation of the Juniper stem extract.
FIG. 5 is a brain map showing relative low beta changes before and after inhalation of the Juniper stem extract.
FIG. 6 is a brain map showing changes in Ratio of alpha to high beta before and after inhalation of the Juniper stem extract.
7 is a brain map showing the change of relative alpha waves before and after inhalation of the fragrance composition of the juniper trunks combination.
Figure 8 is a brain map showing relative mid beta changes before and after inhalation of the Juniper stem combination perfume composition.
Figure 9 is a brain map showing Ratio of mid beta to theta change before and after inhalation of the Juniper stem combination perfume composition.
Figure 10 is a brain map showing spectral edge frequency 50% of alpha change before and after inhalation of the Juniper stem combination perfume composition.

The present invention relates to a fragrance composition capable of reproducing the fragrance of juniper trees.

More specifically, the present invention provides a fragrance composition recreating the fragrance of juniper tree containing Juniper extract as an active ingredient.

The juniper extract may be extracted from juniper trunks, but is not limited thereto.

The extract can be extracted by a solvent extraction method, but is not limited thereto.

The main components of the extract are selected from the group consisting of hexenal, 2-amylfuran, acetic acid, valeric acid, hexanoic acid, guaiacol, phenylethyl alcohol, 4-vinyl guaiacol, , Syringaldehyde, stearic acid, oleic acid, and linoleic acid, and may contain all of the main components. The components of the extract may be extracted from Juniper stem.

The extract comprises 0.1 to 0.3 parts by weight of hexenyl, 0.1 to 0.3 parts by weight of 2-amylfuran, 0.1 to 0.2 parts by weight of acetic acid, 0.1 to 0.3 part by weight of valeric acid, 0.1 to 0.3 parts by weight of hexanobutyric acid, 0.1 to 0.4 parts by weight of phenyl ethyl alcohol, 0.1 to 1.0 part by weight of 4-vinyl guaiacol, 0.1 to 0.3 parts by weight of child-owned phenol, 1.0 to 3.0 parts by weight of vanillin 5.0 to 10.0 parts by weight of palmitic acid, 1.0 to 7.0 parts by weight of sering azalide, 1.0 to 5.0 parts by weight of stearic acid, 1.0 to 5.0 parts by weight of oleic acid and 1.0 to 5.0 parts by weight of linoleic acid .

The perfume composition may further comprise natural oils and synthetic raw materials. The natural oil is not a synthetic oil produced through a synthetic process, but natural oil or natural oil, but it may be a vegetable oil. In addition, the above-mentioned synthetic raw material is a raw material which is produced by processing a natural raw material by a chemical method. The natural oils and the synthetic raw materials are not limited as long as they are related to the juniper fragrance.

That is, the perfume composition of the present invention may contain extracts from Juniper, natural oils or synthetic fuels to the extracts, or all natural oils and synthetic fuels to the extracts (in the juniper combination).

More specifically, the natural oils may be one or more selected from the group consisting of rosewood oil, clay sage oil, patry oil, olivanum oil, immortelle oil, burdock tar oil, copafu balsam oil, But is not limited thereto. When the natural oil is used, the aroma effect can be exerted. In one embodiment of the present invention, the physiological / psychological effect by the aroma effect is measured.

The natural oil may contain 10.0 to 15.0 parts by weight of rosewood oil, 1.0 to 5.0 parts by weight of clay sage oil, 1.0 to 5.0 parts by weight of patry oil, 10.0 to 20.0 parts by weight of olivanum oil, 1.0-5.0 parts by weight of mustel oil, 0.5-5.0 parts by weight of waxy tar oil, 5.0-10.0 parts by weight of copafu Balsam oil, and 0.5-5.0 parts by weight of cysteine.

The starting material for the synthesis is selected from the group consisting of aldehyde c-6, aldehyde c-8, aldehyde c-7, aldehyde c-9, acetic acid, aldehyde c-10, valeric acid, hexanoic acid, benzyl alcohol, One selected from the group consisting of acetic acid, 4-vinyl guaiacol, child-owned agar, vanillin, myristic acid, palmitic acid, sialingdehyde, stearic acid, oleic acid, linoleic acid and myralecinoid But is not limited thereto.

The aldehyde c-7 is used in an amount of 0.5 to 1.0 part by weight, the aldehyde c-9 is used in an amount of 0.5 to 1.0 part by weight, and the aldehyde c-9 is used in an amount of 0.5 to 1.0 part by weight based on 100 parts by weight of the total perfume composition. 0.1 to 1.0 part by weight of acetic acid, 0.5 to 1.5 parts by weight of aldehyde c-10, 2.0 to 3.0 parts by weight of valeric acid, 6.0 to 8.0 parts by weight of hexanoic acid, 11.0 to 13.0 parts by weight of benzyl alcohol, 0.5 to 1.5 parts by weight of an alcohol, 2.5 to 3.5 parts by weight of an octanoic acid, 1.5 to 2.0 parts by weight of 4-vinylguaiacol, 1.5 to 2.0 parts by weight of a propylene glycol, 1.0 to 2.0 parts by weight of vanillin, 4.0 to 6.0 parts by weight of palmitic acid, 1.0 to 2.0 parts by weight of sialingdehyde, 3.0 to 4.0 parts by weight of stearic acid, 1.0 to 2.0 parts by weight of oleic acid, 1.5 to 2.5 parts by weight of linoleic acid, And 5.0 to 10.0 parts by weight of a resinoid.

The present invention also relates to a composition for external application for skin comprising a fragrance composition recreating the fragrance of juniper tree.

The composition for external application for skin may be formulated into perfume, cosmetics, body lotion and the like, and other components may be suitably selected and compounded in order to achieve the desired effect according to the conventional art.

BEST MODE FOR CARRYING OUT THE INVENTION Hereinafter, the present invention will be described in detail with reference to the following examples. However, the following examples are intended to illustrate the contents of the present invention, but the scope of the present invention is not limited to the following examples. Embodiments of the present invention are provided to more fully describe the present invention to those skilled in the art.

Example  One. Juniper tree  stem Dry  Preparation of extract

Extraction from domestic juniper trunks purchased from medicinal products was performed by solvent extraction. After 150 g of the juniper trunks were ground, 1800 mL of ethanol was added to the Erlenmeyer flask, and the mixture was stirred for 24 hours. After that, the extracts of the juniper trunks were filtered using a vacuum filter, and then concentrated using a vacuum concentrator. The concentrated concrete was suspended in distilled water, and then fractionated three times using diethyl ether. Thereafter, the impurities in the diethyl ether are removed by using anhydrous sodium sulfate (sodium sulfate anhydrous), and the filtrate is concentrated under reduced pressure. The weight of the concentrated concrete was measured and the recovery rate was measured.

Example  2. Juniper tree  stem Dry  Analysis of extracts

2-1. GC - MS  Analysis condition

The analysis conditions of GC-MS are shown in Table 1 below.

 Condition GC (Agilent 7890) -column: HP innowax column 30m x 0.25um x 250mm
-Oven temperature: 60 占 폚, 0 min? 3 占 폚 / min? 250 mm
-injector temp: 250 ° C MS (Agilent 5975) -ion source temp: 230 DEG C
-Quard temp: 150 DEG C
-mode: TIC mold

2-2. GC - MS  Analysis

Table 2 shows the dry extracts of the Junjuku mushroom.

ingredient  content(%) hexanal 0.19 2-amyl furan 0.19 acetic acid 0.12 valeric acid 0.24 hexanoic acid 0.73 guaiacol 0.04 phenylethyl alcohol 0.23 4-vinyl guaiacol 0.71 isoeugenol 0.19 vanillin 1.60 palmitic acid 8.90 syringaldehyde 4.20 stearic acid 2.95 oleic acid 2.12 linoleic acid 2.10 Etc 75.49 100.00

As can be seen from the above, the juniper trunk dry extract contains hexanal, hexanoic acid, 4-vinyl guaiacol, vanillin, syringaldehyde, Stearic acid, linoleic acid, palmitic acid, and some other acids.

Example  3. Juniper stem Dry  A combination perfume composition for reproducing the fragrance of an extract

Based on the analysis of the components of the Junjoo trunk dry extract to obtain generally available raw materials and natural images, a new combination of the natural oil and synthetic materials of Table 3, To prepare a perfume composition.

ingredient  content(%) aldehyde c-6  0.5 to 1.0 aldehyde c-8  1.0 to 2.0 aldehyde c-7  0.5 to 1.0 aldehyde c-9  0.5 to 1.0 acetic acid  0.1 to 1.0 aldehyde c-10  0.5 to 1.5 valeric acid  2.0 to 3.0 hexanoic acid  6.0 to 8.0 benzyl alcohol  11.0 to 13.0 phenylethyl alcohol  0.5 to 1.5 octanoic acid  2.5 to 3.5 4-vinyl guaiacol  1.5 to 2.0 isoeugenol  1.5 to 2.0 vanilline  1.0 to 2.0 myristic acid  3.0 to 4.0 palmitic acid  4.0 to 6.0 syringaldehyde  1.0 to 2.0 stearic acid  3.0 to 4.0 oleic acid  1.0 to 2.0 linoleic acid  1.5 to 2.5 rosewood oil  10.0 to 15.0 clay sage oil  1.0 to 5.0 myrrhe resinoid  5.0 to 10.0 patchouly oil  1.0 to 5.0 olibanum oil  10.0 to 20.0 immortelle oil  1.0 to 5.0 birch tar oil  0.5 to 5.0 copahu balsam oil  5.0 to 10.0 ciste oil  0.5 to 5.0 Etc  1.0 to 10.0  100.0

Example  4. Juniper stem Dry  Physiological / Psychological Effects of Extract and Combined Fragrance Composition

The effects of neurophysiologic inhalation of dry juniper stem extract and combination fragrance composition on EEG were compared and analyzed.

4-1. Experiment environment

EEG was measured in 10 subjects (5 men and 5 women). The measurement site was a 32.4㎡ (9.8 pyeong) laboratory with a constant temperature (23˚C) and humidity (50% EEG was measured in a stable state.

4-2. Brain wave device

The instrument used for EEG was the QEEG-8 System (LXE3208, LAXTHA Inc. Korea). EEG signals were measured using a data collection device and an analysis program (Telescan).

4-3. How to measure

Electroencephalogram electrodes: 10-20 International Standard Electrode Attachment method was used to attach EEG electrodes to EEG electrodes, which were attached to EEG electrodes, to the prefrontal, frontal, temporal, and parietal regions of the subjects. Respectively.

4-4. Experimental Method ( Incense suction )

The vial's essential oil was poured into the stomach paper (13 cm) and kept at a distance of about 3 cm from the nose of the subject. In the state where the subject closed his eyes, the subject was exposed to the pre-incense (unstimulated) (Samples with low recovery were inhaled into the vials).

4-5. Data Analysis

Data were processed by batch processing by extracting only the EEG signals measured for 20 seconds during 1 minute measurement, and a corresponding sample T test was performed using a statistical analysis program of SPSS 18.0 version (measured at the time of perfusion of each sample Data of the subjects whose handwriting was found among the EEG signals were excluded).

The EEG brain mapping (3D brain mapping program) is used to show EEG changes during pre-inhalation and during inhalation.

The Value 7 color bar shown on the left side of FIG. 2 shows the mean data of the EEG signals measured before and after the incense suction, and shows different averages for EEG indicators (RMB, ALB, etc.). The higher the mean value of the EEG signals measured at Fp1, Fp2, F3, F4, T3, T4, P3 and P4, the higher the color is, and the lower the average value, the lower the color. For example, when alpha wave appeared at T3 position, blue color appeared before incense suction and purple color appeared during inhalation.

Example  5. EEG changes due to inhalation

5-1. AB Measurement of an indicator

Absolute beta power spectrum (AB) means the absolute power spectrum value of theta wave region of 4-8 Hz in EEG spectrum. Means the absolute power spectrum value of the beta wave region of 13 to 30 Hz. The beta wave is activated when there is a mental activity, such as appearing when doing general work, conscious action, or information processing.

Electroencephalogram (EEG) measurements before and after inhalation of juniper trunks showed significant increase in the right frontal lobe (F4) (p <0.05). These results indicate that the concentration of beta - wave induced by the right frontal region (F4) was increased by the inhalation of juniper trunks extract. (Table 4). These results indicate that the concentration of beta - wave induced by the right frontal region (F4) was increased by the inhalation of juniper trunks extract. Table 4 below shows changes in absolute beta waves before and after inhalation of the fragrance of juniper trunks extract.

AB (Absolute beta power spectrum) Site Inhalation N Mean SD t-test p Fp1 Before 9 12.0967 4.0720 -.638 .541 during 9 12.5364 3.3928 Fp2 Before 9 10.5920 4.4262 -2,287 .051 during 9 11.6229 3.9064 F3 Before 9 14.5991 5.1137 -.982 .355 during 9 15.2637 5.0497 F4 Before 9 11.7209 4.3319 -2.525 .036 during 9 12.7431 4.0869 T3 Before 9 19.5333 26.8041 .894 .397 during 9 18.3960 23.4186 T4 Before 9 9.7179 6.2470 .005 .996 during 9 9.7132 4.8890 P3 Before 9 19.7012 6.2947 1.988 .082 during 9 18.0152 6.7268 P4 Before 9 14.9542 4.4538 .200 .846 during 9 14.7896 4.5829

Fp1: Left prefrontal, Fp2: Right prefrontal

F3: Left frontal, F4: Right frontal

T3: Left temporal, T4: Right temporal,

P3: Left parietal, P4: Right parietal

These results could be confirmed by the brain map. As shown in FIG. 3, it was confirmed that the blue color changed to blue in the prefrontal region of the right frontal lobe of the nasal decidua extract before and after the inhalation. These results indicate that the concentration of beta - wave induced by the right frontal region (F4) was increased by the inhalation of juniper trunks extract.

5-2. RB  Measurement of an indicator

The relative beta power spectrum (RB) index is the absolute power ratio of the beta band to the absolute power of the whole frequency region in the EEG spectrum. The absolute beta ratio is the absolute value of the beta power spectrum (13-30 Hz) divided by the entire frequency range (4-50 Hz) it means.

The beta wave, which is activated when there is a general work or conscious behavior, or when there is mental activity such as information processing, shows that the right frontal lobe (F4) (P <0.05), respectively (Table 5). These results indicate that the Brain was awakened by the increase of beta wave induced in the right frontal lobe (F4) region at the time of inhalation of juniper trunks extract. Table 5 below shows the changes in relative beta waves before and after inhalation of the fragrance of juniper trunks extract.

Relative beta power spectrum (RB) Site Inhalation N Mean SD t-test p Fp1 Before 9 .1908 .0600 -1.362 .210 during 9 .2098 .0731 Fp2 Before 9 .1737 .0602 -2,267 .053 during 9 .2014 .0698 F3 Before 9 .1782 .0627 -1.824 .106 during 9 .2070 .0797 F4 Before 9 .1634 .0633 -2.593 .032 during 9 .1949 .0781 T3 Before 9 .2519 .1206 -1.001 .346 during 9 .2705 .1236 T4 Before 9 .2516 .1108 -1.031 .333 during 9 .2747 .0975 P3 Before 9 .2406 .0792 -.526 .613 during 9 .2519 .0913 P4 Before 9 .2382 .0865 -158 .878 during 9 .2412 .0754

Fp1: Left prefrontal, Fp2: Right prefrontal

F3: Left frontal, F4: Right frontal

T3: Left temporal, T4: Right temporal,

P3: Left parietal, P4: Right parietal

These results were confirmed by the brain map. As shown in FIG. 4, it was confirmed that the purple color changed to blue in the prefrontal region of the right frontal lobe of the nasal decidua extract before inhalation. This implies that the brain was awakened by the influence of the beta wave induced in the right frontal lobe.

5-3. Relative low beta power spectrum value

The relative low beta power spectrum (RLB) index is the absolute power ratio of the low beta band to the absolute power of the whole frequency region in the EEG spectrum, divided by the low beta wave region (12 to 15 Hz) into the entire frequency region (4 to 50 Hz) Means a spectral value.

The low beta wave is called sensory motor rhythm (SMR wave) and predominates in the relatively simple task of paying attention while minimizing the activity of the motor cortex. EEG showed a significant increase in the right prefrontal cortex (Fp2) (p <0.05) (Table 6). These results indicate that the concentration of attention is increased and the brain is awakened by the increase of the low beta wave induced in the right frontal lobe (F4) region at the time of inhaling the juniper trunks extract. Table 6 below shows changes in relative low beta waves before and after incense suction of Juniper stem extract.

Relative low beta power spectrum (RLB) Site Inhalation N Mean SD t-test p Fp1 Before 9 .0581 .0148 -1,272 .239 during 9 .0632 .0146 Fp2 Before 9 .0523 .0140 -2.663 .029 during 9 .0611 .0169 F3 Before 9 .0552 .0162 -1,692 .129 during 9 .0633 .0196 F4 Before 9 .0504 .0163 -2.032 .077 during 9 .0613 .0196 T3 Before 9 .0864 .0241 -1.330 .220 during 9 .0963 .0374 T4 Before 9 .0687 .0255 -1.668 .134 during 9 .0839 .0292 P3 Before 9 .1349 .0780 -.193 .852 during 9 .1394 .1098 P4 Before 9 .1221 .0723 -.747 .476 during 9 .1402 .0977

Fp1: Left prefrontal, Fp2: Right prefrontal

F3: Left frontal, F4: Right frontal

T3: Left temporal, T4: Right temporal,

P3: Left parietal, P4: Right parietal

These results were confirmed by the brain map. As shown in FIG. 5, it can be seen that the purple to blue color changes in the right prefrontal region (Fp2) and the frontal region of the pre-inhalation state of the juniper trunks extract and in the inhaled state. This means that brain activity is activated by optimization after inhaling the fragrance of Juniper stem extract.

5-4. Ratio of alpha to high beta value

The Ratio of alpha to high beta (RAHB) index refers to the spectral value obtained by dividing the alpha wave region (8-13 Hz) into the high beta wave region (20-30 Hz) with the alpha / high beta ratio in the EEG spectrum. The results of EEG measurements before and after inhalation of juniper trunks showed significant increase in the right frontal lobe (F4) (Table 7). These results indicate that brain stress is increased by the effect of alpha to high beta waves induced in the right frontal lobe when inhaling the juniper stem extract. Table 7 below shows the change in Ratio of alpha to high beta before and after incense suction of Juniper stem extract.

RAHB (Ratio of alpha to high beta) Site Inhalation N Mean SD t-test p Fp1 Before 9 10.0694 .7746 1.169 .276 during 9 10.1458 .5475 Fp2 Before 9 10.1042 .7395 1.941 .088 during 9 10.1528 .5617 F3 Before 9 10.0417 .7597 1.421 .193 during 9 10.1319 .5698 F4 Before 9 10.0833 .7454 2.322 .049 during 9 10.1250 .5745 T3 Before 9 10.3125 .6680 1.212 .260 during 9 10.2569 .6023 T4 Before 9 10.2917 .6518 1.390 .202 during 9 10.2431 .6063 P3 Before 9 10.4028 .8655 .941 .374 during 9 10.5556 .7619 P4 Before 9 10.2917 .8053 1.018 .338 during 9 10.4514 .7666

Fp1: Left prefrontal, Fp2: Right prefrontal

F3: Left frontal, F4: Right frontal

T3: Left temporal, T4: Right temporal,

P3: Left parietal, P4: Right parietal

These results can also be confirmed by the brain map. As shown in FIG. 6, it can be seen that the color changes from red to green in the vicinity of the right frontal lobe (F4) before the incense suction and after the inhalation of the juniper trunks extract. This means that brain stress is increased by the influence of alpha to high beta waves induced in the right frontal region (F4).

Example  6. Junzoo tree trunk combination perfume composition incense inhalation EEG changes

6-1. Relative alpha power spectrum value

Relative alpha power spectrum (RA) Indicator is the ratio of the absolute power of the alpha wave in the 8 ~ 10 Hz band, based on the absolute power of the whole frequency band. Alpha waves increase when brain function is relaxed and stable.

The results of EEG measurements before and after inhalation of the perfume composition showed significant increase in the right temporal lobe (T4) (p <0.05) (Table 8). This suggests that the morphological composition of the Juniper stem combination reached a stable state due to the increase of alpha waves induced in the right temporal lobe (T4) region during perfusion of perfume composition. Table 8 below shows changes in relative alpha waves before and after inhalation of the fragrance composition of the Juniper stem combination.

Relative alpha power spectrum (RA) Site Inhalation N Mean SD t-test p Fp1 Before 9 .4841 .1387 -.451 .662 during 9 .4955 .1014 Fp2 Before 9 .5045 .1430 -.419 .685 during 9 .5168 .1114 F3 Before 9 .5020 .1495 -.101 .922 during 9 .5052 .1042 F4 Before 9 .5252 .1541 -.620 .551 during 9 .5426 .1118 T3 Before 9 .3968 .1142 -.292 .777 during 9 .4037 .1066 T4 Before 9 .3539 .1902 -2.759 .022 during 9 .4253 .1878 P3 Before 9 .4945 .1268 .020 .984 during 9 .4941 .1061 P4 Before 9 .5181 .1318 -068 .947 during 9 .5193 .1351

Fp1: Left prefrontal, Fp2: Right prefrontal

F3: Left frontal, F4: Right frontal

T3: Left temporal, T4: Right temporal,

P3: Left parietal, P4: Right parietal

These results can be confirmed by the brain map. As shown in FIG. 7, it can be seen that the color changes from purple to green before the inhalation of the fragrance composition perfume composition and the right temporal region of the inhalation state. Juniper stem combination Perfume composition Inhalation means that the alpha wave induced in the right temporal lobe (T4) area has reached a stable state.

6-2. Relative mid beta power spectrum value

The relative mid-beta power spectrum (RMB) index refers to the ratio of the absolute beta power of the 15-20 Hz band to the absolute power of the entire frequency band.

The prevalence of RMB indices in predicting relatively high-stress thinking activities, such as calculations and mental arithmetic, was higher in the left temporal lobe (T3 ) (P <0.05), respectively (Table 9). These results indicate that concentration of the Juniper stem combination perfume composition upon inhalation increases. Table 9 below shows changes in relative mid beta waves before and after inhalation of the fragrance composition of the Juniper stem combination.

Relative mid beta power spectrum (RMB) Site Inhalation N Mean SD t-test p Fp1 Before 9 .0740 .0257 -.423 .682 during 9 .0767 .0260 Fp2 Before 9 .0689 .0242 -.463 .654 during 9 .0723 .0264 F3 Before 9 .0711 .0200 -1.621 .139 during 9 .0787 .0284 F4 Before 9 .0629 .0169 -1.669 .129 during 9 .0747 .0307 T3 Before 9 .0946 .0213 -2.332 .045 during 9 .1093 .0348 T4 Before 9 .1166 .0511 1.191 .264 during 9 .1061 .0488 P3 Before 9 .0853 .0220 -2.115 .064 during 9 .0985 .0314 P4 Before 9 .0794 .0186 -2.071 .068 during 9 .0934 .0345

Fp1: Left prefrontal, Fp2: Right prefrontal

F3: Left frontal, F4: Right frontal

T3: Left temporal, T4: Right temporal,

P3: Left parietal, P4: Right parietal

These results could be confirmed by the brain map. As shown in FIG. 8, it was confirmed that the color changes from blue to red on the left temporal region before suction of the fragrance composition perfume composition and the suction state of the juniper trunks combination. Juniper tree trunk combination perfume composition This means that concentration is increased when perfume is inhaled.

6-3. Ratio of mid beta to theta value

Ratio of mid-beta to theta (RMT) is the mid-beta / theta ratio. The RMT is a mid beta wave, which refers to the ability to pay attention to a specific target, divided by theta wave during sleepiness or meditation, with theta wave less and mid beta wave higher . (P <0.05) (Table 10). The results of the electroencephalogram (EEG) of the perfume composition showed that there was a significant increase in the right parietal lobe (P4). These results indicate that when the perfume composition is inhaled, the brain is activated and the concentration state is increased. Table 10 below shows the Ratio of mid beta to theta before and after inhalation of the Juniper stem combination perfume composition.

Ratio of mid beta to theta (RMT) Site Inhalation N Mean SD t-test p Fp1 Before 9 .3032 .1151 -1.544 .157 during 9 .3730 .1751 Fp2 Before 9 .2966 .1412 -1.371 .204 during 9 .3488 .1705 F3 Before 9 .2924 .1290 -1.440 .184 during 9 .3447 .1792 F4 Before 9 .2633 .1186 -1.786 .108 during 9 .3293 .1601 T3 Before 9 .5046 .2517 -1.323 .218 during 9 .5851 .3153 T4 Before 9 1.5521 2.0241 1.458 .179 during 9 1.0070 1.0675 P3 Before 9 .4200 .1837 -2.163 .059 during 9 .5072 .1784 P4 Before 9 .4159 .1574 -2.358 .043 during 9 .5158 .2066

Fp1: Left prefrontal, Fp2: Right prefrontal

F3: Left frontal, F4: Right frontal

T3: Left temporal, T4: Right temporal,

P3: Left parietal, P4: Right parietal

These results can be confirmed by the brain map. As shown in FIG. 9, it can be seen that the color changes from red to green in the right parietal region and the right temporal region in the pre-inhalation and inhalation state of the fragrance composition of the juniper stem combination. Juniper tree trunk combination perfume composition This means that the brain is activated when perfume is inhaled to increase concentration.

6-4. Spectral edge frequency  50% of alpha spectrum band value

Spectral edge frequency 50% of the alpha spectrum band (ASEF) index is an alpha wave SEF50, which is a comfortable EEG index indicating relaxation of body and mind. The results of EEG measurements before and after inhalation of the perfume composition showed significant decrease in the right prefrontal cortex (Fp2) (p <0.05). (Table 11). These results indicate that the pleasantness of the brain is reduced and awakened when the perfume composition is inhaled. Table 11 below shows changes in spectral edge frequency 50% of alpha waves before and after inhalation of the fragrance composition of the juniper trunks combination.

ASEF (Spectral edge frequency 50% of alpha spectrum band) Site Inhalation N Mean SD t-test p Fp1 Before 9 10.2000 .5431 1.468 .176 during 9 10.0500 .5110 Fp2 Before 9 10.2563 .5762 2.363 .042 during 9 10.0625 .5303 F3 Before 9 10.2063 .5287 1.818 .102 during 9 10.0625 .4714 F4 Before 9 10.1563 .5553 .891 .396 during 9 10.0563 .4836 T3 Before 9 10.1875 .6194 .119 .908 during 9 10.1750 .4005 T4 Before 9 10.2188 .5239 .891 .396 during 9 10.1188 .4845 P3 Before 9 10.2125 .7627 -1.106 .297 during 9 10.3125 .5833 P4 Before 9 10.2563 .8071 -.900 .391 during 9 10.3813 .6315

Fp1: Left prefrontal, Fp2: Right prefrontal

F3: Left frontal, F4: Right frontal

T3: Left temporal, T4: Right temporal,

P3: Left parietal, P4: Right parietal

These results could be confirmed by the brain map. As shown in FIG. 10, it was confirmed that the color changed from green to purple at the prefrontal region of the pre-inhalation and inhalation state of the fragrance composition of the juniper trunks combination. These results indicate that the pleasantness of the brain is reduced and awakened when the perfume composition is inhaled.

[Manufacturing Example]

The fragrance composition as shown in Table 12 was prepared by blending the fragrance composition having similarity to the fragrance of the Juniper stem extract as described above.

Perfume containing fragrance compositions recreating the fragrance of juniper trunks Junjuku tree trunk fragrance reproduction reproduction combination fragrance 15 wt% Alcohol 80 wt% water 4 wt% Pigment Suitable amount Sunscreen Suitable amount

Claims (7)

A fragrance composition recreating the fragrance of juniper tree containing juniper fruit extract as an active ingredient. The method according to claim 1,
Wherein the extract is extracted from a juniper tree trunk. The method according to claim 1,
The main components of the extract are selected from the group consisting of hexenal, 2-amylfuran, acetic acid, valeric acid, hexanoic acid, guaiacol, phenylethyl alcohol, 4-vinyl guaiacol, , Syringaldehyde, stearic acid, oleic acid, and linoleic acid. The fragrance composition recreates the fragrance of the juniper tree. The method according to claim 1,
Wherein the perfume composition further comprises a natural oil and a synthetic raw material. 5. The method of claim 4,
Wherein the natural oil is at least one selected from the group consisting of rosewood oil, clay sage oil, patry oil, olivanum oil, immortelle oil, burdock tar oil, copafu balsam oil, and cyste oil. A perfume composition recreating the fragrance of wood. 5. The method of claim 4,
The starting material for the synthesis is selected from the group consisting of aldehyde c-6, aldehyde c-8, aldehyde c-7, aldehyde c-9, acetic acid, aldehyde c-10, valeric acid, hexanoic acid, benzyl alcohol, One selected from the group consisting of acetic acid, 4-vinyl guaiacol, child-owned agar, vanillin, myristic acid, palmitic acid, sialingdehyde, stearic acid, oleic acid, linoleic acid and myralecinoid By weight based on the total weight of the fragrance composition. A composition for external application for skin comprising the perfume composition according to any one of claims 1 to 6.

Images