KR20150022753A - 베타-아밀로이드의 체외 감소를 위한 신규 조성물 및 이의 제조 방법 - Google Patents

베타-아밀로이드의 체외 감소를 위한 신규 조성물 및 이의 제조 방법 Download PDF

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KR20150022753A
KR20150022753A KR20147030161A KR20147030161A KR20150022753A KR 20150022753 A KR20150022753 A KR 20150022753A KR 20147030161 A KR20147030161 A KR 20147030161A KR 20147030161 A KR20147030161 A KR 20147030161A KR 20150022753 A KR20150022753 A KR 20150022753A
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South Korea
Prior art keywords
beta
amyloid
blood
capture
peptide
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Korean (ko)
Inventor
로게리오 비. 주니어 산토스
스탠리 스테인
친나스워미 카시나탄
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아미렉스 파마슈티컬즈, 인코포레이티드
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Publication of KR20150022753A publication Critical patent/KR20150022753A/ko
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/22Affinity chromatography or related techniques based upon selective absorption processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654Dialysates therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711Alzheimer's disease; Amyloid plaque core protein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2207/00Methods of manufacture, assembly or production

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Emergency Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • External Artificial Organs (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
KR20147030161A 2012-04-26 2013-01-30 베타-아밀로이드의 체외 감소를 위한 신규 조성물 및 이의 제조 방법 Ceased KR20150022753A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261638672P 2012-04-26 2012-04-26
US61/638,672 2012-04-26
PH1/2013/000037A PH12013000037A1 (en) 2013-01-30 2013-01-30 Novel composition for extracorporeal reduction of beta-amyloids and process for producing thereof
PCT/PH2013/000005 WO2013162387A1 (en) 2012-04-26 2013-01-30 Novel composition for extracorporeal reduction of beta-amyloids and process for producing thereof
PH1-2013-000037 2013-01-30

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020187030342A Division KR20180117226A (ko) 2012-04-26 2013-01-30 베타-아밀로이드의 체외 감소를 위한 신규 조성물 및 이의 제조 방법

Publications (1)

Publication Number Publication Date
KR20150022753A true KR20150022753A (ko) 2015-03-04

Family

ID=49483563

Family Applications (2)

Application Number Title Priority Date Filing Date
KR20147030161A Ceased KR20150022753A (ko) 2012-04-26 2013-01-30 베타-아밀로이드의 체외 감소를 위한 신규 조성물 및 이의 제조 방법
KR1020187030342A Ceased KR20180117226A (ko) 2012-04-26 2013-01-30 베타-아밀로이드의 체외 감소를 위한 신규 조성물 및 이의 제조 방법

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020187030342A Ceased KR20180117226A (ko) 2012-04-26 2013-01-30 베타-아밀로이드의 체외 감소를 위한 신규 조성물 및 이의 제조 방법

Country Status (19)

Country Link
US (1) US20150087591A1 (enExample)
EP (1) EP2841447B1 (enExample)
JP (1) JP2015515491A (enExample)
KR (2) KR20150022753A (enExample)
CN (2) CN104662032A (enExample)
AU (2) AU2013253098A1 (enExample)
CA (1) CA2871585A1 (enExample)
DK (1) DK2841447T3 (enExample)
ES (1) ES2685374T3 (enExample)
HR (1) HRP20181365T1 (enExample)
IN (1) IN2014MN02137A (enExample)
LT (1) LT2841447T (enExample)
PH (1) PH12013000037A1 (enExample)
PL (1) PL2841447T3 (enExample)
RS (1) RS57651B1 (enExample)
SG (1) SG11201406972UA (enExample)
SI (1) SI2841447T1 (enExample)
SM (1) SMT201800445T1 (enExample)
WO (1) WO2013162387A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106800590B (zh) * 2015-11-25 2021-04-09 杭州智鹤丹谷生物医药有限公司 一种结合多种淀粉样蛋白单体和聚集体的多肽及其应用
CN105651840B (zh) * 2016-04-01 2017-12-26 商丘师范学院 一种检测β‑淀粉样蛋白寡聚体的类免疫电化学传感器及其制备方法
CN109954128A (zh) * 2019-03-08 2019-07-02 南开大学 一种可干扰β-淀粉样蛋白聚集并协助清除的功能化纳米凝胶及制备方法
CN114933635B (zh) * 2021-08-29 2023-05-19 武汉夫图生物科技有限公司 纳米小肽fh及其在制备治疗及预防眼底血管疾病药物中的应用
US20230201438A1 (en) * 2021-12-23 2023-06-29 Fresenius Medical Care Holdings, Inc. Compounds, systems, and techniques for removal of peripheral amyloid beta peptide with albumin binding competitors
CN115337388A (zh) * 2022-07-01 2022-11-15 南方医科大学 一种抗菌和预防hpv病毒的按需释放凝胶及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5223199B2 (enExample) * 1972-05-27 1977-06-22
JPS4942189A (enExample) * 1972-08-29 1974-04-20
CA2214247C (en) * 1995-03-14 2004-02-10 Praecis Pharmaceuticals Incorporated Modulators of amyloid aggregation
JPH09157283A (ja) * 1995-12-13 1997-06-17 Tatsuaki Yamaguchi 燐酸吸着コロイド
US6022859A (en) * 1996-11-15 2000-02-08 Wisconsin Alumni Research Foundation Inhibitors of β-amyloid toxicity
WO2004056318A2 (en) * 2002-12-19 2004-07-08 New York University Method for treating amyloid disease
US20060069010A1 (en) * 2003-10-17 2006-03-30 Senicure Llc Detoxification depot for Alzheimer's disease
US20070092508A1 (en) * 2005-10-21 2007-04-26 Recombiant Technologies, Llc Detoxification depot for Alzheimer's disease
EP2501412B1 (en) * 2009-11-18 2017-03-29 Nektar Therapeutics Salt form of a multi-arm polymer-drug conjugate
CN102108119A (zh) * 2009-12-25 2011-06-29 天津键凯科技有限公司 多臂聚乙二醇衍生物及其与药物的结合物和凝胶
JP5843345B2 (ja) * 2010-07-08 2016-01-13 旭化成メディカル株式会社 β−アミロイド除去システム

Also Published As

Publication number Publication date
EP2841447A4 (en) 2015-10-28
CN104662032A (zh) 2015-05-27
LT2841447T (lt) 2018-09-10
DK2841447T3 (en) 2018-09-03
ES2685374T3 (es) 2018-10-08
AU2016208257A1 (en) 2016-08-11
SI2841447T1 (sl) 2018-10-30
SMT201800445T1 (it) 2018-09-13
CA2871585A1 (en) 2013-10-31
SG11201406972UA (en) 2014-11-27
AU2016208257B2 (en) 2018-08-16
HRP20181365T1 (hr) 2018-10-19
US20150087591A1 (en) 2015-03-26
EP2841447B1 (en) 2018-06-13
RS57651B1 (sr) 2018-11-30
KR20180117226A (ko) 2018-10-26
CN109731169A (zh) 2019-05-10
EP2841447A1 (en) 2015-03-04
IN2014MN02137A (enExample) 2015-08-21
PL2841447T3 (pl) 2019-03-29
JP2015515491A (ja) 2015-05-28
AU2013253098A1 (en) 2014-11-13
PH12013000037A1 (en) 2013-10-14
WO2013162387A1 (en) 2013-10-31
AU2013253098A2 (en) 2015-04-30

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