PH12013000037A1 - Novel composition for extracorporeal reduction of beta-amyloids and process for producing thereof - Google Patents

Novel composition for extracorporeal reduction of beta-amyloids and process for producing thereof

Info

Publication number
PH12013000037A1
PH12013000037A1 PH1/2013/000037A PH12013000037A PH12013000037A1 PH 12013000037 A1 PH12013000037 A1 PH 12013000037A1 PH 12013000037 A PH12013000037 A PH 12013000037A PH 12013000037 A1 PH12013000037 A1 PH 12013000037A1
Authority
PH
Philippines
Prior art keywords
beta
amyloids
composition
subject
producing
Prior art date
Application number
PH1/2013/000037A
Other languages
English (en)
Inventor
Kasinathan Chinnaswamy
B Santos Rogelio Jr
Stein Stanley
Original Assignee
Amylex Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CN201811292445.6A priority Critical patent/CN109731169A/zh
Priority to SM20180445T priority patent/SMT201800445T1/it
Priority to KR1020187030342A priority patent/KR20180117226A/ko
Priority to EP13781268.1A priority patent/EP2841447B1/en
Priority to DK13781268.1T priority patent/DK2841447T3/en
Priority to CA2871585A priority patent/CA2871585A1/en
Priority to US14/397,486 priority patent/US20150087591A1/en
Priority to CN201380027665.5A priority patent/CN104662032A/zh
Priority to PH1/2013/000037A priority patent/PH12013000037A1/en
Priority to LTEP13781268.1T priority patent/LT2841447T/lt
Priority to SG11201406972UA priority patent/SG11201406972UA/en
Priority to RS20181008A priority patent/RS57651B1/sr
Priority to PL13781268T priority patent/PL2841447T3/pl
Priority to PCT/PH2013/000005 priority patent/WO2013162387A1/en
Application filed by Amylex Pharmaceuticals Inc filed Critical Amylex Pharmaceuticals Inc
Priority to JP2015508893A priority patent/JP2015515491A/ja
Priority to KR20147030161A priority patent/KR20150022753A/ko
Priority to AU2013253098A priority patent/AU2013253098A1/en
Priority to SI201331147T priority patent/SI2841447T1/sl
Priority to IN2137MUN2014 priority patent/IN2014MN02137A/en
Priority to HRP20181365TT priority patent/HRP20181365T1/hr
Priority to ES13781268.1T priority patent/ES2685374T3/es
Publication of PH12013000037A1 publication Critical patent/PH12013000037A1/en
Priority to AU2016208257A priority patent/AU2016208257B2/en
Priority to CY181100895T priority patent/CY1120610T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654—Dialysates therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2207/00—Methods of manufacture, assembly or production

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Emergency Medicine (AREA)
  • Analytical Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • External Artificial Organs (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
PH1/2013/000037A 2012-04-26 2013-01-30 Novel composition for extracorporeal reduction of beta-amyloids and process for producing thereof PH12013000037A1 (en)

Priority Applications (23)

Application Number Priority Date Filing Date Title
PL13781268T PL2841447T3 (pl) 2012-04-26 2013-01-30 Nowa kompozycja dopozaustrojowej redukcji beta-amyloidów oraz procesu ich wytwarzania
KR1020187030342A KR20180117226A (ko) 2012-04-26 2013-01-30 베타-아밀로이드의 체외 감소를 위한 신규 조성물 및 이의 제조 방법
EP13781268.1A EP2841447B1 (en) 2012-04-26 2013-01-30 Novel composition for extracorporeal reduction of beta-amyloids and process for producing thereof
DK13781268.1T DK2841447T3 (en) 2012-04-26 2013-01-30 Hitherto UNKNOWN COMPOSITION FOR EXTRACORPORAL REDUCTION OF BETA AMYLOIDS AND METHOD FOR PREPARING IT
CA2871585A CA2871585A1 (en) 2012-04-26 2013-01-30 Novel composition for extracorporeal reduction of beta-amyloids and process for producing thereof
US14/397,486 US20150087591A1 (en) 2012-04-26 2013-01-30 Novel Composition for Extracorporeal Reduction of Beta-Amyloids and Process for Producing Thereof
CN201380027665.5A CN104662032A (zh) 2012-04-26 2013-01-30 用于体外减少β-淀粉样蛋白的新型组合物及其制备方法
PH1/2013/000037A PH12013000037A1 (en) 2013-01-30 2013-01-30 Novel composition for extracorporeal reduction of beta-amyloids and process for producing thereof
LTEP13781268.1T LT2841447T (lt) 2012-04-26 2013-01-30 Nauja kompozicija, skirta beta-amiloidų ekstrakorporaliniam sumažinimui, ir jos gavimo būdas
SG11201406972UA SG11201406972UA (en) 2012-04-26 2013-01-30 Novel composition for extracorporeal reduction of beta-amyloids and process for producing thereof
RS20181008A RS57651B1 (sr) 2012-04-26 2013-01-30 Nova supstanca za vantelesno smanjenje beta-amiloida i postupak za njenu proizvodnju
CN201811292445.6A CN109731169A (zh) 2012-04-26 2013-01-30 用于体外减少β-淀粉样蛋白的新型组合物及其制备方法
ES13781268.1T ES2685374T3 (es) 2012-04-26 2013-01-30 Nueva composición para la reducción extracorpórea de beta amiloides y procedimiento de producción de la misma
PCT/PH2013/000005 WO2013162387A1 (en) 2012-04-26 2013-01-30 Novel composition for extracorporeal reduction of beta-amyloids and process for producing thereof
JP2015508893A JP2015515491A (ja) 2012-04-26 2013-01-30 β−アミロイドの体外的減少のための新規組成物及びその製造方法
KR20147030161A KR20150022753A (ko) 2012-04-26 2013-01-30 베타-아밀로이드의 체외 감소를 위한 신규 조성물 및 이의 제조 방법
AU2013253098A AU2013253098A1 (en) 2012-04-26 2013-01-30 Novel composition for extracorporeal reduction of Beta-Amyloids and process for producing thereof
SI201331147T SI2841447T1 (sl) 2012-04-26 2013-01-30 Novi sestavek za zunajtelesno redukcijo beta-amiloidov in postopek za njega izdelavo
IN2137MUN2014 IN2014MN02137A (enExample) 2012-04-26 2013-01-30
HRP20181365TT HRP20181365T1 (hr) 2012-04-26 2013-01-30 Novi sastav za izvantjelesno smanjenje beta-amiloida i postupak njegove proizvodnje
SM20180445T SMT201800445T1 (it) 2012-04-26 2013-01-30 Composizione innovativa per la riduzione extracorporea di beta-amiloidi e processo per la relativa produzione
AU2016208257A AU2016208257B2 (en) 2012-04-26 2016-07-25 Novel composition for extracorporeal reduction of beta-amyloids and process for producing thereof
CY181100895T CY1120610T1 (el) 2012-04-26 2018-08-28 Νεα συνθεση για την εξωσωματικη μειωση των βητα-αμυλοειδων και διαδικασια παραγωγης αυτης

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PH1/2013/000037A PH12013000037A1 (en) 2013-01-30 2013-01-30 Novel composition for extracorporeal reduction of beta-amyloids and process for producing thereof

Publications (1)

Publication Number Publication Date
PH12013000037A1 true PH12013000037A1 (en) 2013-10-14

Family

ID=49483563

Family Applications (1)

Application Number Title Priority Date Filing Date
PH1/2013/000037A PH12013000037A1 (en) 2012-04-26 2013-01-30 Novel composition for extracorporeal reduction of beta-amyloids and process for producing thereof

Country Status (19)

Country Link
US (1) US20150087591A1 (enExample)
EP (1) EP2841447B1 (enExample)
JP (1) JP2015515491A (enExample)
KR (2) KR20150022753A (enExample)
CN (2) CN104662032A (enExample)
AU (2) AU2013253098A1 (enExample)
CA (1) CA2871585A1 (enExample)
DK (1) DK2841447T3 (enExample)
ES (1) ES2685374T3 (enExample)
HR (1) HRP20181365T1 (enExample)
IN (1) IN2014MN02137A (enExample)
LT (1) LT2841447T (enExample)
PH (1) PH12013000037A1 (enExample)
PL (1) PL2841447T3 (enExample)
RS (1) RS57651B1 (enExample)
SG (1) SG11201406972UA (enExample)
SI (1) SI2841447T1 (enExample)
SM (1) SMT201800445T1 (enExample)
WO (1) WO2013162387A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106800590B (zh) * 2015-11-25 2021-04-09 杭州智鹤丹谷生物医药有限公司 一种结合多种淀粉样蛋白单体和聚集体的多肽及其应用
CN105651840B (zh) * 2016-04-01 2017-12-26 商丘师范学院 一种检测β‑淀粉样蛋白寡聚体的类免疫电化学传感器及其制备方法
CN109954128A (zh) * 2019-03-08 2019-07-02 南开大学 一种可干扰β-淀粉样蛋白聚集并协助清除的功能化纳米凝胶及制备方法
CN114933635B (zh) * 2021-08-29 2023-05-19 武汉夫图生物科技有限公司 纳米小肽fh及其在制备治疗及预防眼底血管疾病药物中的应用
US20230201438A1 (en) * 2021-12-23 2023-06-29 Fresenius Medical Care Holdings, Inc. Compounds, systems, and techniques for removal of peripheral amyloid beta peptide with albumin binding competitors
CN115337388A (zh) * 2022-07-01 2022-11-15 南方医科大学 一种抗菌和预防hpv病毒的按需释放凝胶及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5223199B2 (enExample) * 1972-05-27 1977-06-22
JPS4942189A (enExample) * 1972-08-29 1974-04-20
CA2214247C (en) * 1995-03-14 2004-02-10 Praecis Pharmaceuticals Incorporated Modulators of amyloid aggregation
JPH09157283A (ja) * 1995-12-13 1997-06-17 Tatsuaki Yamaguchi 燐酸吸着コロイド
US6022859A (en) * 1996-11-15 2000-02-08 Wisconsin Alumni Research Foundation Inhibitors of β-amyloid toxicity
WO2004056318A2 (en) * 2002-12-19 2004-07-08 New York University Method for treating amyloid disease
US20060069010A1 (en) * 2003-10-17 2006-03-30 Senicure Llc Detoxification depot for Alzheimer's disease
US20070092508A1 (en) * 2005-10-21 2007-04-26 Recombiant Technologies, Llc Detoxification depot for Alzheimer's disease
EP2501412B1 (en) * 2009-11-18 2017-03-29 Nektar Therapeutics Salt form of a multi-arm polymer-drug conjugate
CN102108119A (zh) * 2009-12-25 2011-06-29 天津键凯科技有限公司 多臂聚乙二醇衍生物及其与药物的结合物和凝胶
JP5843345B2 (ja) * 2010-07-08 2016-01-13 旭化成メディカル株式会社 β−アミロイド除去システム

Also Published As

Publication number Publication date
EP2841447A4 (en) 2015-10-28
CN104662032A (zh) 2015-05-27
LT2841447T (lt) 2018-09-10
DK2841447T3 (en) 2018-09-03
ES2685374T3 (es) 2018-10-08
AU2016208257A1 (en) 2016-08-11
SI2841447T1 (sl) 2018-10-30
SMT201800445T1 (it) 2018-09-13
CA2871585A1 (en) 2013-10-31
SG11201406972UA (en) 2014-11-27
KR20150022753A (ko) 2015-03-04
AU2016208257B2 (en) 2018-08-16
HRP20181365T1 (hr) 2018-10-19
US20150087591A1 (en) 2015-03-26
EP2841447B1 (en) 2018-06-13
RS57651B1 (sr) 2018-11-30
KR20180117226A (ko) 2018-10-26
CN109731169A (zh) 2019-05-10
EP2841447A1 (en) 2015-03-04
IN2014MN02137A (enExample) 2015-08-21
PL2841447T3 (pl) 2019-03-29
JP2015515491A (ja) 2015-05-28
AU2013253098A1 (en) 2014-11-13
WO2013162387A1 (en) 2013-10-31
AU2013253098A2 (en) 2015-04-30

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