AU2013253098A1 - Novel composition for extracorporeal reduction of Beta-Amyloids and process for producing thereof - Google Patents

Novel composition for extracorporeal reduction of Beta-Amyloids and process for producing thereof Download PDF

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Publication number
AU2013253098A1
AU2013253098A1 AU2013253098A AU2013253098A AU2013253098A1 AU 2013253098 A1 AU2013253098 A1 AU 2013253098A1 AU 2013253098 A AU2013253098 A AU 2013253098A AU 2013253098 A AU2013253098 A AU 2013253098A AU 2013253098 A1 AU2013253098 A1 AU 2013253098A1
Authority
AU
Australia
Prior art keywords
beta
blood
capturing
binding agent
amyloid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2013253098A
Other languages
English (en)
Other versions
AU2013253098A2 (en
Inventor
Chinnaswamy Kasinathan
Rogelio B. Santos Jr.
Stanley Stein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amylex Pharmaceuticals Inc
Original Assignee
Amylex Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amylex Pharmaceuticals Inc filed Critical Amylex Pharmaceuticals Inc
Publication of AU2013253098A1 publication Critical patent/AU2013253098A1/en
Priority to AU2014101449A priority Critical patent/AU2014101449A6/en
Publication of AU2013253098A2 publication Critical patent/AU2013253098A2/en
Priority to AU2016208257A priority patent/AU2016208257B2/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/22Affinity chromatography or related techniques based upon selective absorption processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654Dialysates therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711Alzheimer's disease; Amyloid plaque core protein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2207/00Methods of manufacture, assembly or production

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Neurology (AREA)
  • Analytical Chemistry (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • External Artificial Organs (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
AU2013253098A 2012-04-26 2013-01-30 Novel composition for extracorporeal reduction of Beta-Amyloids and process for producing thereof Abandoned AU2013253098A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2014101449A AU2014101449A6 (en) 2012-04-26 2014-12-08 Novel composition for extracorporeal reduction of beta-amyloids and process for producing thereof
AU2016208257A AU2016208257B2 (en) 2012-04-26 2016-07-25 Novel composition for extracorporeal reduction of beta-amyloids and process for producing thereof

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261638672P 2012-04-26 2012-04-26
US61/638,672 2012-04-26
PH1/2013/000037A PH12013000037A1 (en) 2013-01-30 2013-01-30 Novel composition for extracorporeal reduction of beta-amyloids and process for producing thereof
PH1-2013-000037 2013-01-30
PCT/PH2013/000005 WO2013162387A1 (en) 2012-04-26 2013-01-30 Novel composition for extracorporeal reduction of beta-amyloids and process for producing thereof

Related Child Applications (2)

Application Number Title Priority Date Filing Date
AU2014101449A Division AU2014101449A6 (en) 2012-04-26 2014-12-08 Novel composition for extracorporeal reduction of beta-amyloids and process for producing thereof
AU2016208257A Division AU2016208257B2 (en) 2012-04-26 2016-07-25 Novel composition for extracorporeal reduction of beta-amyloids and process for producing thereof

Publications (2)

Publication Number Publication Date
AU2013253098A1 true AU2013253098A1 (en) 2014-11-13
AU2013253098A2 AU2013253098A2 (en) 2015-04-30

Family

ID=49483563

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2013253098A Abandoned AU2013253098A1 (en) 2012-04-26 2013-01-30 Novel composition for extracorporeal reduction of Beta-Amyloids and process for producing thereof
AU2016208257A Ceased AU2016208257B2 (en) 2012-04-26 2016-07-25 Novel composition for extracorporeal reduction of beta-amyloids and process for producing thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2016208257A Ceased AU2016208257B2 (en) 2012-04-26 2016-07-25 Novel composition for extracorporeal reduction of beta-amyloids and process for producing thereof

Country Status (19)

Country Link
US (1) US20150087591A1 (enExample)
EP (1) EP2841447B1 (enExample)
JP (1) JP2015515491A (enExample)
KR (2) KR20180117226A (enExample)
CN (2) CN104662032A (enExample)
AU (2) AU2013253098A1 (enExample)
CA (1) CA2871585A1 (enExample)
DK (1) DK2841447T3 (enExample)
ES (1) ES2685374T3 (enExample)
HR (1) HRP20181365T1 (enExample)
IN (1) IN2014MN02137A (enExample)
LT (1) LT2841447T (enExample)
PH (1) PH12013000037A1 (enExample)
PL (1) PL2841447T3 (enExample)
RS (1) RS57651B1 (enExample)
SG (1) SG11201406972UA (enExample)
SI (1) SI2841447T1 (enExample)
SM (1) SMT201800445T1 (enExample)
WO (1) WO2013162387A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106800590B (zh) * 2015-11-25 2021-04-09 杭州智鹤丹谷生物医药有限公司 一种结合多种淀粉样蛋白单体和聚集体的多肽及其应用
CN105651840B (zh) * 2016-04-01 2017-12-26 商丘师范学院 一种检测β‑淀粉样蛋白寡聚体的类免疫电化学传感器及其制备方法
CN109954128A (zh) * 2019-03-08 2019-07-02 南开大学 一种可干扰β-淀粉样蛋白聚集并协助清除的功能化纳米凝胶及制备方法
CN114933635B (zh) * 2021-08-29 2023-05-19 武汉夫图生物科技有限公司 纳米小肽fh及其在制备治疗及预防眼底血管疾病药物中的应用
US20230201438A1 (en) * 2021-12-23 2023-06-29 Fresenius Medical Care Holdings, Inc. Compounds, systems, and techniques for removal of peripheral amyloid beta peptide with albumin binding competitors
CN115337388A (zh) * 2022-07-01 2022-11-15 南方医科大学 一种抗菌和预防hpv病毒的按需释放凝胶及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5223199B2 (enExample) * 1972-05-27 1977-06-22
JPS4942189A (enExample) * 1972-08-29 1974-04-20
CA2214247C (en) * 1995-03-14 2004-02-10 Praecis Pharmaceuticals Incorporated Modulators of amyloid aggregation
JPH09157283A (ja) * 1995-12-13 1997-06-17 Tatsuaki Yamaguchi 燐酸吸着コロイド
US6022859A (en) * 1996-11-15 2000-02-08 Wisconsin Alumni Research Foundation Inhibitors of β-amyloid toxicity
WO2004056318A2 (en) * 2002-12-19 2004-07-08 New York University Method for treating amyloid disease
US20060069010A1 (en) * 2003-10-17 2006-03-30 Senicure Llc Detoxification depot for Alzheimer's disease
US20070092508A1 (en) * 2005-10-21 2007-04-26 Recombiant Technologies, Llc Detoxification depot for Alzheimer's disease
EA024533B1 (ru) * 2009-11-18 2016-09-30 Нектар Терапьютикс Формы солей кислот конъюгатов полимер-лекарственное средство
CN103755949B (zh) * 2009-12-25 2016-04-13 天津键凯科技有限公司 多臂聚乙二醇衍生物及其与药物的结合物和凝胶
JP5843345B2 (ja) * 2010-07-08 2016-01-13 旭化成メディカル株式会社 β−アミロイド除去システム

Also Published As

Publication number Publication date
US20150087591A1 (en) 2015-03-26
WO2013162387A1 (en) 2013-10-31
EP2841447A1 (en) 2015-03-04
RS57651B1 (sr) 2018-11-30
EP2841447B1 (en) 2018-06-13
SMT201800445T1 (it) 2018-09-13
CN109731169A (zh) 2019-05-10
JP2015515491A (ja) 2015-05-28
DK2841447T3 (en) 2018-09-03
IN2014MN02137A (enExample) 2015-08-21
ES2685374T3 (es) 2018-10-08
CA2871585A1 (en) 2013-10-31
KR20150022753A (ko) 2015-03-04
SG11201406972UA (en) 2014-11-27
LT2841447T (lt) 2018-09-10
EP2841447A4 (en) 2015-10-28
PL2841447T3 (pl) 2019-03-29
CN104662032A (zh) 2015-05-27
AU2013253098A2 (en) 2015-04-30
AU2016208257A1 (en) 2016-08-11
SI2841447T1 (sl) 2018-10-30
HRP20181365T1 (hr) 2018-10-19
KR20180117226A (ko) 2018-10-26
PH12013000037A1 (en) 2013-10-14
AU2016208257B2 (en) 2018-08-16

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Legal Events

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DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 19 MAR 2015

MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted