KR20150015488A - 2-아미노-4-아릴티아졸 화합물의 아미드 및 그의 염 - Google Patents

2-아미노-4-아릴티아졸 화합물의 아미드 및 그의 염 Download PDF

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Publication number
KR20150015488A
KR20150015488A KR1020147033855A KR20147033855A KR20150015488A KR 20150015488 A KR20150015488 A KR 20150015488A KR 1020147033855 A KR1020147033855 A KR 1020147033855A KR 20147033855 A KR20147033855 A KR 20147033855A KR 20150015488 A KR20150015488 A KR 20150015488A
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KR
South Korea
Prior art keywords
formula
compound
trifluoromethyl
tetrahydrothieno
phenyl
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Abandoned
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KR1020147033855A
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English (en)
Korean (ko)
Inventor
수레쉬 마하데브 카담
아브라함 토마스
수쿠마르 신하
수케르티 쿠마르
비핀 파르소탐 칸사그라
사친 가베인
산딥 반두 칸다게일
샤일레시 파와스
자얀트 프라카슈라오 파틸
샤일렌드라 바데인
바브나 미슈라
라제시 드위베디
Original Assignee
그렌마크 파머수티칼스 에스. 아.
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54193746&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR20150015488(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 그렌마크 파머수티칼스 에스. 아. filed Critical 그렌마크 파머수티칼스 에스. 아.
Publication of KR20150015488A publication Critical patent/KR20150015488A/ko
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/553—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
KR1020147033855A 2012-06-08 2013-06-08 2-아미노-4-아릴티아졸 화합물의 아미드 및 그의 염 Abandoned KR20150015488A (ko)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
IN1687/MUM/2012 2012-06-08
IN1687MU2012 2012-06-08
US201261665282P 2012-06-27 2012-06-27
US61/665,282 2012-06-27
IN3519MU2012 2012-12-13
IN3519/MUM/2012 2012-12-13
US201261748016P 2012-12-31 2012-12-31
US61/748,016 2012-12-31
PCT/IB2013/054703 WO2013183035A2 (en) 2012-06-08 2013-06-08 Amides of 2-amino-4-arylthiazole compounds and their salts

Publications (1)

Publication Number Publication Date
KR20150015488A true KR20150015488A (ko) 2015-02-10

Family

ID=54193746

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020147033855A Abandoned KR20150015488A (ko) 2012-06-08 2013-06-08 2-아미노-4-아릴티아졸 화합물의 아미드 및 그의 염

Country Status (22)

Country Link
US (1) US9458173B2 (cg-RX-API-DMAC7.html)
EP (1) EP2858999B1 (cg-RX-API-DMAC7.html)
JP (1) JP5989900B2 (cg-RX-API-DMAC7.html)
KR (1) KR20150015488A (cg-RX-API-DMAC7.html)
CN (1) CN104350058A (cg-RX-API-DMAC7.html)
AP (1) AP3546A (cg-RX-API-DMAC7.html)
AU (1) AU2013273118B2 (cg-RX-API-DMAC7.html)
BR (1) BR112014029155A2 (cg-RX-API-DMAC7.html)
CA (1) CA2873570C (cg-RX-API-DMAC7.html)
CL (1) CL2014003317A1 (cg-RX-API-DMAC7.html)
EA (1) EA031334B1 (cg-RX-API-DMAC7.html)
HK (1) HK1207643A1 (cg-RX-API-DMAC7.html)
IL (1) IL236084A0 (cg-RX-API-DMAC7.html)
IN (1) IN2014MN02467A (cg-RX-API-DMAC7.html)
MX (1) MX354014B (cg-RX-API-DMAC7.html)
MY (1) MY165622A (cg-RX-API-DMAC7.html)
NZ (1) NZ701721A (cg-RX-API-DMAC7.html)
PE (1) PE20142306A1 (cg-RX-API-DMAC7.html)
PH (1) PH12014502685A1 (cg-RX-API-DMAC7.html)
SG (1) SG11201408093PA (cg-RX-API-DMAC7.html)
WO (1) WO2013183035A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA201500082B (cg-RX-API-DMAC7.html)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR091279A1 (es) 2012-06-08 2015-01-21 Gilead Sciences Inc Inhibidores macrociclicos de virus flaviviridae
PT2861604T (pt) 2012-06-08 2017-05-05 Gilead Sciences Inc Inibidores macrocíclicos de vírus flaviridae
EP3010489A1 (en) 2013-06-20 2016-04-27 Glenmark Pharmaceuticals S.A. Nanoparticulate formulation comprising a trpa1 antagonist
JP6573968B2 (ja) * 2014-08-11 2019-09-11 ハイドラ バイオサイエンシズ インコーポレイテッドＨｙｄｒａ Ｂｉｏｓｃｉｅｎｃｅｓ，Ｉｎｃ． ＴＲＰＣ５調節因子としての、精神神経障害の処置のためのチエノおよびフロ［２，３−ｄ］ピリミジン−２，４［１Ｈ，３Ｈ］−ジオン誘導体
WO2016042501A1 (en) * 2014-09-16 2016-03-24 Glenmark Pharmaceuticals S.A. Trpa1 antagonist for the treatment of pain associated to diabetic neuropathic pain
TW202321229A (zh) 2021-08-18 2023-06-01 美商富曼西公司 殺真菌的取代的雜環化合物
CN114671875A (zh) * 2022-04-27 2022-06-28 成都施贝康生物医药科技有限公司 新型二氢嘧啶类化合物、异构体或盐及其制备方法和用途

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2248231A1 (de) 1972-10-02 1974-04-11 Basf Ag 3-aminoisothiazolo eckige klammer auf 3,4-d eckige klammer zu pyrimidine
SE9701398D0 (sv) 1997-04-15 1997-04-15 Astra Pharma Prod Novel compounds
ES2193839B1 (es) * 2001-06-22 2005-02-16 Almirall Prodesfarma, S.A. Nuevos derivados de 6-fenildihidropirrolpirimidindiona.
AU2003253165A1 (en) * 2002-08-13 2004-02-25 Warner-Lambert Company Llc Pyrimidine fused bicyclic metalloproteinase inhibitors
US6890923B2 (en) 2002-12-16 2005-05-10 Astrazeneca Ab Compounds
WO2004055054A1 (en) 2002-12-18 2004-07-01 Novartis Ag Anktm1, a cold-activated trp-like channel expressed in nociceptive neurons
EP1657238A4 (en) * 2003-08-22 2008-12-03 Takeda Pharmaceutical CONDENSATE PYRIMIDINE DERIVATIVE AND ITS USE
WO2005077959A1 (en) 2004-02-11 2005-08-25 Smithkline Beecham Corporation Pth agonists
WO2005089206A2 (en) 2004-03-13 2005-09-29 Irm Llc Modulators of ion channel trpa1
EP1847541A4 (en) 2005-02-03 2009-12-30 Takeda Pharmaceutical CONDENSED PYRIMIDINE DERIVATIVE AND USE THEREOF
US20070032531A1 (en) 2005-08-04 2007-02-08 Apogee Biotechnology Corporation Sphingosine kinase inhibitors and methods of their use
US20070105920A1 (en) 2005-11-08 2007-05-10 Akzo Nobel N.V. 2-(Benzimidazol-1-Yl)-N-(4-phenylthiazol-2-yl) acetamide derivatives
AU2006327181A1 (en) 2005-12-22 2007-06-28 Hydra Biosciences, Inc. TRPA1 inhibitors for treating pain
CN101454318A (zh) * 2006-03-22 2009-06-10 阿斯利康(瑞典)有限公司 吡啶并嘧啶衍生物及其作为pde4抑制剂的用途
TW200800997A (en) 2006-03-22 2008-01-01 Astrazeneca Ab Chemical compounds
JP2011201776A (ja) 2008-07-23 2011-10-13 Mochida Pharmaceut Co Ltd ヘテロシクリデン−ｎ−（３，４−ジヒドロ−２（１ｈ）−キナゾリノン−５−イル）アセトアミド誘導体
AR065081A1 (es) 2007-01-29 2009-05-13 Xenon Pharmaceuticals Inc Compuestos de quinazolinona y pirimidona fusionados y composicion farmaceutica
ES2609912T3 (es) 2007-06-22 2017-04-25 Hydra Biosciences, Inc. Compuestos de 2,6-dioxo, -2,3-dihidro-1h-purina útiles para el tratamiento de trastornos relacionados con la actividad del canal trpa1
US7951814B2 (en) * 2008-06-17 2011-05-31 Glenmark Pharmaceuticals, S.A. Quinazolinedione derivatives as TRPA1 modulators
WO2009158719A2 (en) 2008-06-27 2009-12-30 Hydra Biosciences, Inc. Methods and compositions for treating disorders
SI2411393T1 (sl) 2009-03-23 2014-03-31 Glenmark Pharmaceuticals S.A. Kondenzirani pirimidin-dionski derivati kot TRPA 1 modulatorji
WO2010109328A1 (en) 2009-03-23 2010-09-30 Glenmark Pharmaceuticals, S.A. Isothiazolo-pyrimidinedione derivatives as trpa1 modulators
US8623880B2 (en) 2009-03-23 2014-01-07 Glenmark Pharmaceuticals S.A. Fused pyrimidine-dione derivatives as TRPA1 modulators
EP2411395B1 (en) * 2009-03-23 2013-05-29 Glenmark Pharmaceuticals S.A. Furopyrimidinedione derivatives as trpa1 modulators
PE20140234A1 (es) 2010-12-20 2014-03-08 Glenmark Phamaceuticals S A Compuestos de 2-amino-4-ariltiazol como antagonistas de trpa1

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Publication number Publication date
BR112014029155A2 (pt) 2017-06-27
HK1207643A1 (en) 2016-02-05
PE20142306A1 (es) 2015-01-16
AP2014008076A0 (en) 2014-11-30
ZA201500082B (en) 2015-12-23
EP2858999A2 (en) 2015-04-15
EP2858999B1 (en) 2017-05-10
AU2013273118A1 (en) 2014-11-27
JP5989900B2 (ja) 2016-09-07
PH12014502685B1 (en) 2015-01-26
US20150111038A1 (en) 2015-04-23
MX354014B (es) 2018-02-08
MY165622A (en) 2018-04-18
CA2873570A1 (en) 2013-12-12
CN104350058A (zh) 2015-02-11
AP3546A (en) 2016-01-14
WO2013183035A3 (en) 2014-02-27
CL2014003317A1 (es) 2015-02-13
AU2013273118B2 (en) 2015-11-05
SG11201408093PA (en) 2015-01-29
IN2014MN02467A (cg-RX-API-DMAC7.html) 2015-07-10
EA031334B1 (ru) 2018-12-28
CA2873570C (en) 2016-11-01
IL236084A0 (en) 2015-02-01
EA201492054A1 (ru) 2016-08-31
PH12014502685A1 (en) 2015-01-26
MX2014014482A (es) 2015-06-05
WO2013183035A2 (en) 2013-12-12
JP2015520183A (ja) 2015-07-16
NZ701721A (en) 2016-03-31
US9458173B2 (en) 2016-10-04

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