KR20150008889A - Ａｌｋ１ 수용체 및 리간드 길항제 및 그의 용도 - Google Patents

Ａｌｋ１ 수용체 및 리간드 길항제 및 그의 용도 Download PDF

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KR20150008889A
KR20150008889A KR1020147033523A KR20147033523A KR20150008889A KR 20150008889 A KR20150008889 A KR 20150008889A KR 1020147033523 A KR1020147033523 A KR 1020147033523A KR 20147033523 A KR20147033523 A KR 20147033523A KR 20150008889 A KR20150008889 A KR 20150008889A
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alk1
polypeptide
leu
val
pro
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Korean (ko)
Inventor
아샤 그린베르그
존 노프
래빈드라 쿠마
로버트 스콧 피어샐
제이스버 시라
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악셀레론 파마 인코포레이티드
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Publication of KR20150008889A publication Critical patent/KR20150008889A/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
KR1020147033523A 2006-11-02 2007-11-02 Ａｌｋ１ 수용체 및 리간드 길항제 및 그의 용도 Withdrawn KR20150008889A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85659206P 2006-11-02 2006-11-02
US60/856,592 2006-11-02
PCT/US2007/023217 WO2008057461A2 (en) 2006-11-02 2007-11-02 Alk1 receptor and ligand antagonists and uses thereof

Related Parent Applications (1)

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KR1020097011291A Division KR101581961B1 (ko) 2006-11-02 2007-11-02 Ａｌｋ１ 수용체 및 리간드 길항제 및 그의 용도

Related Child Applications (1)

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KR1020177001896A Division KR20170012582A (ko) 2006-11-02 2007-11-02 Ａｌｋ１ 수용체 및 리간드 길항제 및 그의 용도

Publications (1)

Publication Number Publication Date
KR20150008889A true KR20150008889A (ko) 2015-01-23

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Family Applications (3)

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KR1020147033523A Withdrawn KR20150008889A (ko) 2006-11-02 2007-11-02 Ａｌｋ１ 수용체 및 리간드 길항제 및 그의 용도
KR1020177001896A Ceased KR20170012582A (ko) 2006-11-02 2007-11-02 Ａｌｋ１ 수용체 및 리간드 길항제 및 그의 용도
KR1020097011291A Expired - Fee Related KR101581961B1 (ko) 2006-11-02 2007-11-02 Ａｌｋ１ 수용체 및 리간드 길항제 및 그의 용도

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KR1020177001896A Ceased KR20170012582A (ko) 2006-11-02 2007-11-02 Ａｌｋ１ 수용체 및 리간드 길항제 및 그의 용도
KR1020097011291A Expired - Fee Related KR101581961B1 (ko) 2006-11-02 2007-11-02 Ａｌｋ１ 수용체 및 리간드 길항제 및 그의 용도

Country Status (14)

Country Link
US (4) US8455428B2 (https=)
EP (2) EP3181580A1 (https=)
JP (5) JP2010508816A (https=)
KR (3) KR20150008889A (https=)
CN (2) CN111518218A (https=)
AU (1) AU2007317926A1 (https=)
BR (1) BRPI0717964A2 (https=)
CA (1) CA2668411C (https=)
DK (1) DK2087001T3 (https=)
ES (1) ES2612755T3 (https=)
IL (2) IL198522A (https=)
MX (1) MX2009004718A (https=)
RU (2) RU2559532C2 (https=)
WO (1) WO2008057461A2 (https=)

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JP6348448B2 (ja) 2018-06-27
JP2020150955A (ja) 2020-09-24
DK2087001T3 (en) 2017-02-06
CN101652387A (zh) 2010-02-17
IL198522A (en) 2017-06-29
RU2009120695A (ru) 2010-12-10
US20130344067A1 (en) 2013-12-26
CA2668411A1 (en) 2008-05-15
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CN111518218A (zh) 2020-08-11
CA2668411C (en) 2020-02-25
JP2018127471A (ja) 2018-08-16
US12144860B2 (en) 2024-11-19
AU2007317926A1 (en) 2008-05-15
JP2010508816A (ja) 2010-03-25
EP2087001B1 (en) 2016-10-26
IL253035A0 (en) 2017-08-31
BRPI0717964A2 (pt) 2013-12-17
US20220296708A1 (en) 2022-09-22
RU2013134324A (ru) 2015-01-27
JP2015143269A (ja) 2015-08-06
MX2009004718A (es) 2009-06-19
WO2008057461A3 (en) 2009-02-26
US20170354731A1 (en) 2017-12-14
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US8455428B2 (en) 2013-06-04
US20080175844A1 (en) 2008-07-24
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