EP0998561A4 - Trail receptor - Google Patents
Trail receptorInfo
- Publication number
- EP0998561A4 EP0998561A4 EP98934441A EP98934441A EP0998561A4 EP 0998561 A4 EP0998561 A4 EP 0998561A4 EP 98934441 A EP98934441 A EP 98934441A EP 98934441 A EP98934441 A EP 98934441A EP 0998561 A4 EP0998561 A4 EP 0998561A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- trail receptor
- trail
- receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US89211997A | 1997-07-15 | 1997-07-15 | |
US892119 | 1997-07-15 | ||
PCT/US1998/014410 WO1999003992A1 (en) | 1997-07-15 | 1998-07-10 | Trail receptor |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0998561A1 EP0998561A1 (en) | 2000-05-10 |
EP0998561A4 true EP0998561A4 (en) | 2004-08-18 |
Family
ID=25399402
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP98934441A Withdrawn EP0998561A4 (en) | 1997-07-15 | 1998-07-10 | Trail receptor |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0998561A4 (en) |
JP (1) | JP2001510042A (en) |
AU (1) | AU8395798A (en) |
CA (1) | CA2295719A1 (en) |
IL (1) | IL133920A0 (en) |
NZ (1) | NZ501951A (en) |
WO (1) | WO1999003992A1 (en) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6506569B1 (en) | 1997-05-30 | 2003-01-14 | Human Genome Sciences, Inc. | Antibodies to human tumor necrosis factor receptor TR10 |
CA2292790A1 (en) | 1997-05-30 | 1998-12-03 | Human Genome Sciences, Inc. | Human tumor necrosis factor receptor tr10 |
US6252050B1 (en) * | 1998-06-12 | 2001-06-26 | Genentech, Inc. | Method for making monoclonal antibodies and cross-reactive antibodies obtainable by the method |
ATE324377T1 (en) * | 1999-05-28 | 2006-05-15 | Human Genome Sciences Inc | HUMAN TUMOR NECROSIS FACTOR RECEPTOR FC FUSION PROTEINS TR10 |
US6627199B1 (en) | 1999-07-09 | 2003-09-30 | Amgen Inc | Isolation, identification and characterization of tmst2, a novel member of the TNF-receptor supergene family |
WO2001010908A1 (en) | 1999-08-04 | 2001-02-15 | Amgen Inc. | Ntr3, a member of the tnf-receptor supergene family |
AU783682B2 (en) | 1999-08-04 | 2005-11-24 | Amgen, Inc. | Fhm, a novel member of the TNF ligand supergene family |
US7476383B2 (en) | 2000-05-02 | 2009-01-13 | The Uab Research Foundation | Antibody selective for DR4 and uses thereof |
US7279160B2 (en) | 2000-05-02 | 2007-10-09 | The Uab Research Foundation | Combinations of DR5 antibodies and other therapeutic agents |
TWI318983B (en) * | 2000-05-02 | 2010-01-01 | Uab Research Foundation | An antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and uses thereof |
KR100436089B1 (en) * | 2000-07-06 | 2004-06-14 | 설대우 | DNA cassette for the production of secretable recombinant trimeric TRAIL protein, Tetracycline/Doxycycline-inducible Adeno-associated virus(AAV), and combination of both and the gene therapy method thereof |
KR20020056565A (en) * | 2000-12-29 | 2002-07-10 | 황규언 | Three-dimensional structure of human derived apoptotic factor and receptor thereof by X-ray chrystallography and TRAIL deletion mutant protein |
US7064189B2 (en) | 2001-05-25 | 2006-06-20 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to trail receptors |
EP1846034A4 (en) | 2005-02-02 | 2010-11-10 | Uab Research Foundation | Agents and methods related to reducing resistance to apoptosis-inducing death receptor agonists |
CA2780130A1 (en) | 2009-11-05 | 2011-05-12 | The Uab Research Foundation | Treating basal-like genotype cancers |
WO2011116344A2 (en) | 2010-03-18 | 2011-09-22 | The Uab Research Foundation | Targeting cancer stem cells |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998054202A1 (en) * | 1997-05-30 | 1998-12-03 | Human Genome Sciences, Inc. | Human tumor necrosis factor receptor tr10 |
WO1999010484A1 (en) * | 1997-08-26 | 1999-03-04 | Genentech, Inc. | Rtd receptor |
-
1998
- 1998-07-10 JP JP2000503198A patent/JP2001510042A/en active Pending
- 1998-07-10 NZ NZ501951A patent/NZ501951A/en unknown
- 1998-07-10 WO PCT/US1998/014410 patent/WO1999003992A1/en not_active Application Discontinuation
- 1998-07-10 CA CA002295719A patent/CA2295719A1/en not_active Abandoned
- 1998-07-10 IL IL13392098A patent/IL133920A0/en unknown
- 1998-07-10 EP EP98934441A patent/EP0998561A4/en not_active Withdrawn
- 1998-07-10 AU AU83957/98A patent/AU8395798A/en not_active Abandoned
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998054202A1 (en) * | 1997-05-30 | 1998-12-03 | Human Genome Sciences, Inc. | Human tumor necrosis factor receptor tr10 |
WO1999010484A1 (en) * | 1997-08-26 | 1999-03-04 | Genentech, Inc. | Rtd receptor |
Non-Patent Citations (2)
Title |
---|
DEGLI ESPOSITI M A ET AL: "The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain", IMMUNITY, CELL PRESS, US, vol. 7, no. 6, 1 December 1997 (1997-12-01), pages 813 - 820, XP002087442, ISSN: 1074-7613 * |
See also references of WO9903992A1 * |
Also Published As
Publication number | Publication date |
---|---|
WO1999003992A1 (en) | 1999-01-28 |
CA2295719A1 (en) | 1999-01-28 |
JP2001510042A (en) | 2001-07-31 |
IL133920A0 (en) | 2001-04-30 |
NZ501951A (en) | 2001-09-28 |
EP0998561A1 (en) | 2000-05-10 |
AU8395798A (en) | 1999-02-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20000121 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20040701 |
|
18D | Application deemed to be withdrawn |
Effective date: 20040201 |
|
REG | Reference to a national code |
Ref country code: HK Ref legal event code: WD Ref document number: 1028785 Country of ref document: HK |