KR20140051099A - 히알루론산을 이용하는 신장 손상의 평가를 위한 방법 및 조성물 - Google Patents

히알루론산을 이용하는 신장 손상의 평가를 위한 방법 및 조성물 Download PDF

Info

Publication number
KR20140051099A
KR20140051099A KR1020137010404A KR20137010404A KR20140051099A KR 20140051099 A KR20140051099 A KR 20140051099A KR 1020137010404 A KR1020137010404 A KR 1020137010404A KR 20137010404 A KR20137010404 A KR 20137010404A KR 20140051099 A KR20140051099 A KR 20140051099A
Authority
KR
South Korea
Prior art keywords
subject
concentration
rifle
likelihood
measured concentration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020137010404A
Other languages
English (en)
Korean (ko)
Inventor
조셉 앤더버그
제프 그레이
폴 맥퍼슨
케빈 나카무라
제임스 패트릭 캄프
카이 싱바럴
존 에이. 주니어 켈럼
Original Assignee
아스튜트 메디컬 인코포레이티드
유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 아스튜트 메디컬 인코포레이티드, 유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 filed Critical 아스튜트 메디컬 인코포레이티드
Publication of KR20140051099A publication Critical patent/KR20140051099A/ko
Ceased legal-status Critical Current

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/38—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence, e.g. gluco- or galactomannans, Konjac gum, Locust bean gum or Guar gum
    • G01N2400/40—Glycosaminoglycans, i.e. GAG or mucopolysaccharides, e.g. chondroitin sulfate, dermatan sulfate, hyaluronic acid, heparin, heparan sulfate, and related sulfated polysaccharides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/34—Genitourinary disorders
    • G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/56—Staging of a disease; Further complications associated with the disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
KR1020137010404A 2010-09-24 2011-09-23 히알루론산을 이용하는 신장 손상의 평가를 위한 방법 및 조성물 Ceased KR20140051099A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38642110P 2010-09-24 2010-09-24
US61/386,421 2010-09-24
PCT/US2011/053015 WO2012040592A1 (en) 2010-09-24 2011-09-23 Methods and compositions for the evaluation of renal injury using hyaluronic acid

Publications (1)

Publication Number Publication Date
KR20140051099A true KR20140051099A (ko) 2014-04-30

Family

ID=45874188

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020137010404A Ceased KR20140051099A (ko) 2010-09-24 2011-09-23 히알루론산을 이용하는 신장 손상의 평가를 위한 방법 및 조성물

Country Status (13)

Country Link
US (1) US20130252264A1 (enExample)
EP (1) EP2619231B1 (enExample)
JP (1) JP2013541005A (enExample)
KR (1) KR20140051099A (enExample)
CN (2) CN103189394B (enExample)
AU (1) AU2011305197B2 (enExample)
BR (1) BR112013006631A2 (enExample)
CA (1) CA2813011A1 (enExample)
EA (1) EA201390294A1 (enExample)
ES (1) ES2619617T3 (enExample)
MX (1) MX348303B (enExample)
NZ (1) NZ609126A (enExample)
WO (1) WO2012040592A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2882767B1 (en) * 2012-08-11 2023-07-12 Astute Medical, Inc. Evaluating renal injury using hyaluronic acid
CN119643878B (zh) * 2024-12-25 2025-07-25 中国人民解放军总医院第一医学中心 一种检测肾脏纤维化相关疾病的生物标志物及其应用

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5939272A (en) 1989-01-10 1999-08-17 Biosite Diagnostics Incorporated Non-competitive threshold ligand-receptor assays
US5028535A (en) 1989-01-10 1991-07-02 Biosite Diagnostics, Inc. Threshold ligand-receptor assay
US5922615A (en) 1990-03-12 1999-07-13 Biosite Diagnostics Incorporated Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network
WO1992005282A1 (en) 1990-09-14 1992-04-02 Biosite Diagnostics, Inc. Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays
US5955377A (en) 1991-02-11 1999-09-21 Biostar, Inc. Methods and kits for the amplification of thin film based assays
ATE177841T1 (de) 1991-04-10 1999-04-15 Biosite Diagnostics Inc ''crosstalk''- oder übersprech-inhibitoren und ihre verwendung
EP0579767B1 (en) 1991-04-11 2000-08-23 Biosite Diagnostics Inc. Novel conjugates and assays for simultaneous detection of multiple ligands
US5885527A (en) 1992-05-21 1999-03-23 Biosite Diagnostics, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membrances
US6143576A (en) 1992-05-21 2000-11-07 Biosite Diagnostics, Inc. Non-porous diagnostic devices for the controlled movement of reagents
US5494829A (en) 1992-07-31 1996-02-27 Biostar, Inc. Devices and methods for detection of an analyte based upon light interference
US5824799A (en) 1993-09-24 1998-10-20 Biosite Diagnostics Incorporated Hybrid phthalocyanine derivatives and their uses
US6113855A (en) 1996-11-15 2000-09-05 Biosite Diagnostics, Inc. Devices comprising multiple capillarity inducing surfaces
US5947124A (en) 1997-03-11 1999-09-07 Biosite Diagnostics Incorporated Diagnostic for determining the time of a heart attack
US6057098A (en) 1997-04-04 2000-05-02 Biosite Diagnostics, Inc. Polyvalent display libraries
JP2004208693A (ja) * 2002-12-17 2004-07-29 Sanyo Chem Ind Ltd 抗ヒアルロン酸抗体、これを含む試薬キット、抗ヒアルロン酸抗体の製造法及びヒアルロン酸の測定法
WO2005114186A1 (ja) * 2004-05-20 2005-12-01 Wako Pure Chemical Industries, Ltd. ヒアルロン酸バインディングプロテインを用いたヒアルロン酸の測定方法
US20090285761A1 (en) * 2008-04-18 2009-11-19 Pharmacophotonics, Llc D/B/A Fast Diagnostics Renal Function Analysis Method and Apparatus
WO2009146450A2 (en) * 2008-05-30 2009-12-03 Therapeutic Monitoring Services, L.L.C. Methods for monitoring immunosuppressant drug levels, renal function, and hepatic function using small volume samples
US8673574B2 (en) * 2008-08-21 2014-03-18 Pxbiosciences Llc Diagnosis and monitoring of renal failure using peptide biomarkers
NZ610356A (en) * 2008-08-28 2015-03-27 Astute Medical Inc Methods and compositions for diagnosis and prognosis of renal injury and renal failure
US8501489B2 (en) * 2008-09-26 2013-08-06 University of Pittsburgh—of the Commonwealth System of Higher Education Urinary biomarkers to predict long-term dialysis
EP2393937A4 (en) * 2009-02-06 2012-08-08 Astute Medical Inc METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE
JP5763098B2 (ja) * 2009-12-20 2015-08-12 アスチュート メディカル，インコーポレイテッド 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物

Also Published As

Publication number Publication date
BR112013006631A2 (pt) 2017-10-24
NZ609126A (en) 2015-05-29
CN106248921A8 (zh) 2017-07-21
AU2011305197B2 (en) 2015-06-11
EP2619231A4 (en) 2014-04-30
ES2619617T3 (es) 2017-06-26
MX2013003204A (es) 2013-06-05
JP2013541005A (ja) 2013-11-07
EP2619231B1 (en) 2016-12-21
WO2012040592A1 (en) 2012-03-29
AU2011305197A1 (en) 2013-05-02
CN106248921A (zh) 2016-12-21
CA2813011A1 (en) 2012-03-29
CN103189394A (zh) 2013-07-03
EP2619231A1 (en) 2013-07-31
CN103189394B (zh) 2016-08-17
EA201390294A1 (ru) 2013-09-30
US20130252264A1 (en) 2013-09-26
MX348303B (es) 2017-06-06

Similar Documents

Publication Publication Date Title
KR101940014B1 (ko) 신손상 및 신부전을 진단 및 예측하는 방법 및 조성물
KR102003258B1 (ko) 신손상 및 신부전을 진단 및 예측하는 방법 및 조성물
KR20140051754A (ko) 신장 손상 및 신부전의 진단 및 예후를 위한 방법 및 조성물
KR20140074307A (ko) 신장 손상 및 신부전의 진단 및 예후진단을 위한 방법 및 조성물
JP5981144B2 (ja) 腎損傷および腎不全の診断および予後診断
KR102431003B1 (ko) 신손상 및 신부전의 진단 및 예후를 위한 방법 및 조성물
JP2012517594A (ja) 腎損傷および腎不全の診断および予後診断のための方法および組成物
HK1200218A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
KR20120061863A (ko) 신장 손상 및 신부전증의 진단과 예후를 위한 방법 및 조성물
US20190227056A1 (en) Methods and compositions for the evaluation of renal injury using hyaluronic acid
CN107003325A (zh) 用于诊断和预后肾损伤和肾衰竭的方法和组合物
CN103189394B (zh) 利用透明质酸评价肾损伤的方法和组合物
JP6538353B2 (ja) 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物
HK1232598A1 (en) Methods and compositions for the evaluation of renal injury using hyaluronic acid
HK1186198B (en) Methods and compositions for the evaluation of renal injury using hyaluronic acid
HK1186198A (en) Methods and compositions for the evaluation of renal injury using hyaluronic acid
HK1212774B (en) Methods and composition for diagnosis and prognosis of renal injury and renal failure
HK1212774A1 (zh) 用於腎損傷和腎衰竭的診斷及預後方法和組合物
HK1162617B (zh) 腎損傷和腎衰竭的診斷和預後
HK1236620A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1167889B (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1167888B (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1219129A1 (zh) 用於肾损伤和肾衰竭的诊断及预後的方法和组合物
HK1168129B (en) Diagnosis and prognosis of renal injury and renal failure
HK1195128B (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20130423

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20160729

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20180212

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20180430

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20180212

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I