EA201390294A1 - Способы и композиции для оценки повреждения почек с применением гиалуроновой кислоты - Google Patents

Способы и композиции для оценки повреждения почек с применением гиалуроновой кислоты

Info

Publication number
EA201390294A1
EA201390294A1 EA201390294A EA201390294A EA201390294A1 EA 201390294 A1 EA201390294 A1 EA 201390294A1 EA 201390294 A EA201390294 A EA 201390294A EA 201390294 A EA201390294 A EA 201390294A EA 201390294 A1 EA201390294 A1 EA 201390294A1
Authority
EA
Eurasian Patent Office
Prior art keywords
compositions
methods
hyaluronic acid
kidney damage
kidney injury
Prior art date
Application number
EA201390294A
Other languages
English (en)
Inventor
Джозеф Андерберг
Джефф Грей
Пол Макферсон
Кевин Накамура
Джеймс Патрик Кампф
Джон А. мл. Келлум
Кай Сингбартл
Original Assignee
Астьют Медикал, Инк.
Юниверсити Оф Питтсбург - Оф Зе Коммон Уэлс Систем Оф Хайе Эдьюкейшн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Астьют Медикал, Инк., Юниверсити Оф Питтсбург - Оф Зе Коммон Уэлс Систем Оф Хайе Эдьюкейшн filed Critical Астьют Медикал, Инк.
Publication of EA201390294A1 publication Critical patent/EA201390294A1/ru

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/00272-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/38Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence, e.g. gluco- or galactomannans, Konjac gum, Locust bean gum or Guar gum
    • G01N2400/40Glycosaminoglycans, i.e. GAG or mucopolysaccharides, e.g. chondroitin sulfate, dermatan sulfate, hyaluronic acid, heparin, heparan sulfate, and related sulfated polysaccharides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/34Genitourinary disorders
    • G01N2800/347Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/56Staging of a disease; Further complications associated with the disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

Настоящее изобретение относится к способам и композициям для наблюдения за состоянием, диагностики, прогнозирования и определения схемы лечения субъектов, страдающих повреждением почек или предположительно имеющих повреждение почек. В частности, настоящее изобретение относится к применению анализов, позволяющих обнаружить один или более из гиалуроновой кислоты (ГК), в качестве диагностических и прогностических биомаркерных анализов при повреждениях почек.
EA201390294A 2010-09-24 2011-09-23 Способы и композиции для оценки повреждения почек с применением гиалуроновой кислоты EA201390294A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38642110P 2010-09-24 2010-09-24
PCT/US2011/053015 WO2012040592A1 (en) 2010-09-24 2011-09-23 Methods and compositions for the evaluation of renal injury using hyaluronic acid

Publications (1)

Publication Number Publication Date
EA201390294A1 true EA201390294A1 (ru) 2013-09-30

Family

ID=45874188

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201390294A EA201390294A1 (ru) 2010-09-24 2011-09-23 Способы и композиции для оценки повреждения почек с применением гиалуроновой кислоты

Country Status (13)

Country Link
US (1) US20130252264A1 (ru)
EP (1) EP2619231B1 (ru)
JP (1) JP2013541005A (ru)
KR (1) KR20140051099A (ru)
CN (2) CN106248921A (ru)
AU (1) AU2011305197B2 (ru)
BR (1) BR112013006631A2 (ru)
CA (1) CA2813011A1 (ru)
EA (1) EA201390294A1 (ru)
ES (1) ES2619617T3 (ru)
MX (1) MX348303B (ru)
NZ (1) NZ609126A (ru)
WO (1) WO2012040592A1 (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014028339A1 (en) * 2012-08-11 2014-02-20 Astute Medical, Inc. Evaluating renal injury using hyaluronic acid

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5939272A (en) 1989-01-10 1999-08-17 Biosite Diagnostics Incorporated Non-competitive threshold ligand-receptor assays
US5028535A (en) 1989-01-10 1991-07-02 Biosite Diagnostics, Inc. Threshold ligand-receptor assay
US5922615A (en) 1990-03-12 1999-07-13 Biosite Diagnostics Incorporated Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network
CA2072758A1 (en) 1990-09-14 1992-03-15 Kenneth Francis Buechler Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays
US5955377A (en) 1991-02-11 1999-09-21 Biostar, Inc. Methods and kits for the amplification of thin film based assays
DE69228682T2 (de) 1991-04-10 1999-07-01 Biosite Diagnostics Inc., San Diego, Calif. "crosstalk"- oder übersprech-inhibitoren und ihre verwendung
DE69231382T2 (de) 1991-04-12 2001-01-25 Biosite Diagnostics Inc., San Diego Neue konjugate und testverfahren für die gleichzeitige bestimmung von multiplen liganden
US6143576A (en) 1992-05-21 2000-11-07 Biosite Diagnostics, Inc. Non-porous diagnostic devices for the controlled movement of reagents
US6019944A (en) 1992-05-21 2000-02-01 Biosite Diagnostics, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membranes
US5494829A (en) 1992-07-31 1996-02-27 Biostar, Inc. Devices and methods for detection of an analyte based upon light interference
US5824799A (en) 1993-09-24 1998-10-20 Biosite Diagnostics Incorporated Hybrid phthalocyanine derivatives and their uses
US6113855A (en) 1996-11-15 2000-09-05 Biosite Diagnostics, Inc. Devices comprising multiple capillarity inducing surfaces
US5947124A (en) 1997-03-11 1999-09-07 Biosite Diagnostics Incorporated Diagnostic for determining the time of a heart attack
US6057098A (en) 1997-04-04 2000-05-02 Biosite Diagnostics, Inc. Polyvalent display libraries
JP2004208693A (ja) * 2002-12-17 2004-07-29 Sanyo Chem Ind Ltd 抗ヒアルロン酸抗体、これを含む試薬キット、抗ヒアルロン酸抗体の製造法及びヒアルロン酸の測定法
ATE516498T1 (de) * 2004-05-20 2011-07-15 Wako Pure Chem Ind Ltd Verfahren zum testen von hyaluronsäure mit hyaluronsäure-bindungsprotein
CA2721846C (en) * 2008-04-18 2021-01-26 Pharmacophotonics, Inc. Renal function analysis method and apparatus
WO2009146450A2 (en) * 2008-05-30 2009-12-03 Therapeutic Monitoring Services, L.L.C. Methods for monitoring immunosuppressant drug levels, renal function, and hepatic function using small volume samples
US8673574B2 (en) * 2008-08-21 2014-03-18 Pxbiosciences Llc Diagnosis and monitoring of renal failure using peptide biomarkers
CA2735587A1 (en) * 2008-08-28 2010-03-04 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
US8501489B2 (en) 2008-09-26 2013-08-06 University of Pittsburgh—of the Commonwealth System of Higher Education Urinary biomarkers to predict long-term dialysis
CN102369293B (zh) * 2009-02-06 2014-05-28 阿斯图特医药公司 肾损伤和肾衰竭的诊断及预后
ES2592386T3 (es) * 2009-12-20 2016-11-29 Astute Medical, Inc. Métodos y composiciones para el diagnóstico y pronóstico de lesión renal e insuficiencia renal

Also Published As

Publication number Publication date
CN103189394A (zh) 2013-07-03
NZ609126A (en) 2015-05-29
AU2011305197B2 (en) 2015-06-11
EP2619231A4 (en) 2014-04-30
AU2011305197A1 (en) 2013-05-02
JP2013541005A (ja) 2013-11-07
KR20140051099A (ko) 2014-04-30
CN103189394B (zh) 2016-08-17
MX2013003204A (es) 2013-06-05
ES2619617T3 (es) 2017-06-26
US20130252264A1 (en) 2013-09-26
CN106248921A8 (zh) 2017-07-21
CN106248921A (zh) 2016-12-21
WO2012040592A1 (en) 2012-03-29
EP2619231B1 (en) 2016-12-21
MX348303B (es) 2017-06-06
EP2619231A1 (en) 2013-07-31
BR112013006631A2 (pt) 2017-10-24
CA2813011A1 (en) 2012-03-29

Similar Documents

Publication Publication Date Title
EA201290711A1 (ru) Способы и композиции для диагностики и прогнозирования повреждений почек и почечной недостаточности
EA201290629A1 (ru) Способы и композиции для диагностики и прогнозирования повреждений почек и почечной недостаточности
EA201290056A1 (ru) Способы и композиции для диагностики и прогнозирования повреждений почек и почечной недостаточности
EP2767833A3 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
EA201490384A1 (ru) Способы и композиции для диагностики и прогнозирования повреждений почек и почечной недостаточности
NZ625423A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
EA201290192A1 (ru) Способы и композиции для диагностики и прогнозирования повреждений почек и почечной недостаточности
NZ605698A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
EA201290311A1 (ru) Факторы риска и прогнозирование инфаркта миокарда
WO2010057184A3 (en) Methods for detection of acute kidney injury in humans
EA201490105A1 (ru) Способы и композиции для диагностики и прогнозирования повреждений почек и почечной недостаточности
BR112015014232A2 (pt) lesão renal aguda
NZ608316A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
NZ624614A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
EA201290106A1 (ru) Способы и композиции для диагностики и прогнозирования повреждения почек и почечной недостаточности
EA201291314A1 (ru) Способы и композиции для диагностики и прогнозирования повреждений почек и почечной недостаточности
IN2014DN08537A (ru)
WO2012139052A3 (en) Antibody biomarkers for diabetes
NZ601648A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
WO2011130647A3 (en) Compositions and methods for characterizing a myopathy
BR112012024175A2 (pt) hbf e a1m como marcadores de estágio precoce para preeclampsia
NZ605561A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
EA201390294A1 (ru) Способы и композиции для оценки повреждения почек с применением гиалуроновой кислоты
NZ601643A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
TR201906195T4 (tr) Niemann pıck hastalığının teşhisi için metot.