BR112013006631A2 - métodos e composições para a avaliação de lesão renal utilizando ácido hialurônico - Google Patents

métodos e composições para a avaliação de lesão renal utilizando ácido hialurônico

Info

Publication number
BR112013006631A2
BR112013006631A2 BR112013006631A BR112013006631A BR112013006631A2 BR 112013006631 A2 BR112013006631 A2 BR 112013006631A2 BR 112013006631 A BR112013006631 A BR 112013006631A BR 112013006631 A BR112013006631 A BR 112013006631A BR 112013006631 A2 BR112013006631 A2 BR 112013006631A2
Authority
BR
Brazil
Prior art keywords
compositions
methods
hyaluronic acid
evaluation
renal injury
Prior art date
Application number
BR112013006631A
Other languages
English (en)
Inventor
Patrick Kampf James
Gray Jeff
A Kellum John Jr
Anderberg Joseph
Singbartl Kai
Nakamura Kevin
Mcpherson Paul
Original Assignee
Astute Medical Inc
Univ Pittsburgh Commonwealth Sys Higher Education
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astute Medical Inc, Univ Pittsburgh Commonwealth Sys Higher Education filed Critical Astute Medical Inc
Publication of BR112013006631A2 publication Critical patent/BR112013006631A2/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/38—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence, e.g. gluco- or galactomannans, e.g. Konjac gum, Locust bean gum, Guar gum
    • G01N2400/40—Glycosaminoglycans, i.e. GAG or mucopolysaccharides, e.g. chondroitin sulfate, dermatan sulfate, hyaluronic acid, heparin, heparan sulfate, and related sulfated polysaccharides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/34—Genitourinary disorders
    • G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/56—Staging of a disease; Further complications associated with the disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

métodos e composições para a avaliação de lesão renal utilizando ácido hialurônico. a presnete invenção se relaciona com os métodos e composições para monitoramento, diagnóstico, prognóstico e determinação dos regimes de tratamento em objetos que sofrem de, ou com suspeita de ter lesão renal. em particular, a invenção se relaciona com o uso de ensaios para detectar um ou mais de ácido hialurônico (ah) como ensaios biomarcadores de prognóstico e diagnóstico em lesões renais.
BR112013006631A 2010-09-24 2011-09-23 métodos e composições para a avaliação de lesão renal utilizando ácido hialurônico BR112013006631A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38642110P 2010-09-24 2010-09-24
PCT/US2011/053015 WO2012040592A1 (en) 2010-09-24 2011-09-23 Methods and compositions for the evaluation of renal injury using hyaluronic acid

Publications (1)

Publication Number Publication Date
BR112013006631A2 true BR112013006631A2 (pt) 2017-10-24

Family

ID=45874188

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013006631A BR112013006631A2 (pt) 2010-09-24 2011-09-23 métodos e composições para a avaliação de lesão renal utilizando ácido hialurônico

Country Status (13)

Country Link
US (1) US20130252264A1 (pt)
EP (1) EP2619231B1 (pt)
JP (1) JP2013541005A (pt)
KR (1) KR20140051099A (pt)
CN (2) CN103189394B (pt)
AU (1) AU2011305197B2 (pt)
BR (1) BR112013006631A2 (pt)
CA (1) CA2813011A1 (pt)
EA (1) EA201390294A1 (pt)
ES (1) ES2619617T3 (pt)
MX (1) MX348303B (pt)
NZ (1) NZ609126A (pt)
WO (1) WO2012040592A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150241415A1 (en) * 2012-08-11 2015-08-27 Astute Medical, Inc. Evaluating renal injury using hyaluronic acid

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5028535A (en) 1989-01-10 1991-07-02 Biosite Diagnostics, Inc. Threshold ligand-receptor assay
US5939272A (en) 1989-01-10 1999-08-17 Biosite Diagnostics Incorporated Non-competitive threshold ligand-receptor assays
US5922615A (en) 1990-03-12 1999-07-13 Biosite Diagnostics Incorporated Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network
CA2072758A1 (en) 1990-09-14 1992-03-15 Kenneth Francis Buechler Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays
US5955377A (en) 1991-02-11 1999-09-21 Biostar, Inc. Methods and kits for the amplification of thin film based assays
CA2107894C (en) 1991-04-10 2003-10-14 Kenneth F. Buechler Crosstalk inhibitors and their uses
ES2150915T3 (es) 1991-04-12 2000-12-16 Biosite Diagnostics Inc Nuevos conjugados y dosificados destinados para la deteccion simultanea de ligandos multiples.
US6143576A (en) 1992-05-21 2000-11-07 Biosite Diagnostics, Inc. Non-porous diagnostic devices for the controlled movement of reagents
US5885527A (en) 1992-05-21 1999-03-23 Biosite Diagnostics, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membrances
US5494829A (en) 1992-07-31 1996-02-27 Biostar, Inc. Devices and methods for detection of an analyte based upon light interference
US5824799A (en) 1993-09-24 1998-10-20 Biosite Diagnostics Incorporated Hybrid phthalocyanine derivatives and their uses
US6113855A (en) 1996-11-15 2000-09-05 Biosite Diagnostics, Inc. Devices comprising multiple capillarity inducing surfaces
US5947124A (en) 1997-03-11 1999-09-07 Biosite Diagnostics Incorporated Diagnostic for determining the time of a heart attack
US6057098A (en) 1997-04-04 2000-05-02 Biosite Diagnostics, Inc. Polyvalent display libraries
JP2004208693A (ja) * 2002-12-17 2004-07-29 Sanyo Chem Ind Ltd 抗ヒアルロン酸抗体、これを含む試薬キット、抗ヒアルロン酸抗体の製造法及びヒアルロン酸の測定法
US20070259380A1 (en) * 2004-05-20 2007-11-08 Kyoichi Sumida Method for Measuring Hyaluronic Acid Using Hyaluronic Acid Binding Protein
WO2009140026A2 (en) * 2008-04-18 2009-11-19 Pharmacophotonics, Llc D/B/A Fast Diagnostics Renal function analysis method and apparatus
US20090298106A1 (en) * 2008-05-30 2009-12-03 Therapeutic Monitoring Services, L.L.C. Methods for Monitoring Immunosuppressant Drug Levels, Renal Function, and Hepatic Function Using Small Volume Samples
US8673574B2 (en) * 2008-08-21 2014-03-18 Pxbiosciences Llc Diagnosis and monitoring of renal failure using peptide biomarkers
CN102187220B (zh) * 2008-08-28 2015-08-19 阿斯图特医药公司 用于诊断和预后肾损伤和肾衰竭的方法和组合物
US8501489B2 (en) * 2008-09-26 2013-08-06 University of Pittsburgh—of the Commonwealth System of Higher Education Urinary biomarkers to predict long-term dialysis
CN106546752A (zh) * 2009-02-06 2017-03-29 阿斯图特医药公司 肾损伤和肾衰竭的诊断及预后
CN104698161A (zh) * 2009-12-20 2015-06-10 阿斯图特医药公司 用于肾损伤和肾衰竭的诊断及预后的方法和组合物

Also Published As

Publication number Publication date
WO2012040592A1 (en) 2012-03-29
CN106248921A8 (zh) 2017-07-21
AU2011305197A1 (en) 2013-05-02
NZ609126A (en) 2015-05-29
MX2013003204A (es) 2013-06-05
JP2013541005A (ja) 2013-11-07
KR20140051099A (ko) 2014-04-30
CN106248921A (zh) 2016-12-21
EP2619231A1 (en) 2013-07-31
AU2011305197B2 (en) 2015-06-11
EP2619231A4 (en) 2014-04-30
CN103189394B (zh) 2016-08-17
EP2619231B1 (en) 2016-12-21
ES2619617T3 (es) 2017-06-26
US20130252264A1 (en) 2013-09-26
CN103189394A (zh) 2013-07-03
CA2813011A1 (en) 2012-03-29
MX348303B (es) 2017-06-06
EA201390294A1 (ru) 2013-09-30

Similar Documents

Publication Publication Date Title
WO2011106746A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
BR112013003391A2 (pt) biomarcadores de câncer pancreático e usos dos mesmos
BR112012019542A2 (pt) "método para avaliar o estado renal em um indivíduo, medição de um ou mais biomarcadores, e, kit"
EP3734280A3 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
EP2767833A3 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
BR112012011230A2 (pt) fatores de risco e previsão de infarto do miocárdio
NZ625423A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
TR201904386T4 (tr) Nükleotidleri içeren nükleozomların saptanmasına yönelik yöntem.
NZ605698A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
NZ608384A (en) Biomarkers of renal injury
NZ630277A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
BR112012032537A2 (pt) biomarcadores de câncer de pulmão e suas utilizações
MX2012001559A (es) Metodos y composiciones para diagnosticos y pronosticos de lesion renal y falla renal.
BR112014011818A2 (pt) método para realizar ensaios de quantificação
MX2011008323A (es) Metodos y composiciones para diagnosis y prognosis de lesion renal y falla renal.
BR112017008218A2 (pt) métodos e composições para diagnóstico e prognóstico de lesão renal e insuficiência renal
MX2019008260A (es) Metodos y composiciones para la evaluacion y tratamiento de lesion renal e insuficiencia renal con base en la medicion del ligando 14 de quimiocina de la porcion c-c.
NZ628085A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
BR112015014232A2 (pt) lesão renal aguda
EA201490105A1 (ru) Способы и композиции для диагностики и прогнозирования повреждений почек и почечной недостаточности
MX2014002030A (es) Biomarcadores de carcinoma de celulas renales y usos de los mismos.
TR201902845T4 (tr) Artritik durumların karakterize edilmesine yönelik bileşimler ve yöntemler.
NZ601648A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
MX2012003168A (es) Metodos y composiciones para diagnosis y prognosis de lesion renal e insuficiencia renal.
BR112012024175A2 (pt) hbf e a1m como marcadores de estágio precoce para preeclampsia

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2532 DE 16-07-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.