KR20140020966A - 간 질환 치료용 약학 조성물 - Google Patents

간 질환 치료용 약학 조성물 Download PDF

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Publication number
KR20140020966A
KR20140020966A KR1020137027665A KR20137027665A KR20140020966A KR 20140020966 A KR20140020966 A KR 20140020966A KR 1020137027665 A KR1020137027665 A KR 1020137027665A KR 20137027665 A KR20137027665 A KR 20137027665A KR 20140020966 A KR20140020966 A KR 20140020966A
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KR
South Korea
Prior art keywords
proanthocyanidin
pharmaceutical composition
liver
improving
plant
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Ceased
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KR1020137027665A
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English (en)
Korean (ko)
Inventor
창샤우펑
마춘씨엔
양쿠오이
린시홍
린첸퉁
황카이웬
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재단법인 공업기술연구원
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Publication of KR20140020966A publication Critical patent/KR20140020966A/ko
Ceased legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/15Pinaceae (Pine family), e.g. pine or cedar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/45Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/87Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
KR1020137027665A 2011-03-22 2011-03-22 간 질환 치료용 약학 조성물 Ceased KR20140020966A (ko)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2011/072045 WO2012126178A2 (zh) 2011-03-22 2011-03-22 减缓肝癌恶化、改善肝功能、改善肝纤维化、改善肝硬化、改善肝发炎及促进受损肝脏再生之药物组合物

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020167033543A Division KR101981378B1 (ko) 2011-03-22 2011-03-22 간 질환 치료용 약학 조성물

Publications (1)

Publication Number Publication Date
KR20140020966A true KR20140020966A (ko) 2014-02-19

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KR1020167033543A Active KR101981378B1 (ko) 2011-03-22 2011-03-22 간 질환 치료용 약학 조성물
KR1020137027665A Ceased KR20140020966A (ko) 2011-03-22 2011-03-22 간 질환 치료용 약학 조성물

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Country Link
EP (1) EP2689777B1 (enExample)
JP (1) JP6166251B2 (enExample)
KR (2) KR101981378B1 (enExample)
CN (1) CN103442709B (enExample)
AU (1) AU2011362905B2 (enExample)
CA (1) CA2830616C (enExample)
DK (1) DK2689777T3 (enExample)
ES (1) ES2668785T3 (enExample)
NO (1) NO2689777T3 (enExample)
PL (1) PL2689777T3 (enExample)
RU (1) RU2561688C2 (enExample)
SG (1) SG193486A1 (enExample)
WO (1) WO2012126178A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022080846A1 (ko) * 2020-10-13 2022-04-21 서울대학교병원 플라본을 포함하는 섬유증의 예방 또는 치료용 조성물

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140179774A1 (en) * 2012-12-26 2014-06-26 Industrial Technology Research Institute Methods for inhibition of shc-1/p66 to combat aging-related diseases
CN104774909A (zh) * 2014-10-17 2015-07-15 江苏大学 一种原花青素诱导肝癌细胞自噬性死亡的分析方法及应用
GB201909709D0 (en) * 2019-07-05 2019-08-21 Univ Liverpool Biomarkers for irritable bowel syndrome
WO2022205137A1 (zh) * 2021-03-31 2022-10-06 贝尔克斯生技股份有限公司 高聚原花青素组合物及其应用
CN115010720B (zh) * 2022-06-02 2023-08-11 中国科学院昆明植物研究所 中甸艾中倍半萜二聚体及其药物组合物与其制备方法和应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6713506B2 (en) * 2000-10-11 2004-03-30 University Of South Florida Tea polyphenol esters and analogs thereof for cancer prevention and treatment
CN1443533A (zh) * 2002-03-07 2003-09-24 程彦杰 原花青素类化合物在用于制备解酒保肝产品方面的用途
TW200505468A (en) * 2003-08-11 2005-02-16 Suntory Ltd Agent for improving hepato-bililary dysfunction
WO2005074632A2 (en) * 2004-01-30 2005-08-18 Mars, Incorporated Methods and compositions for treating cancer
US20070054868A1 (en) * 2005-06-20 2007-03-08 The Trustees Of Columbia University In The City Of New York Synergistic polyphenol compounds, compositions thereof, and uses thereof
JP2008156265A (ja) * 2006-12-22 2008-07-10 Yamagata Prefecture A型プロアントシアニジンオリゴマー画分及びその製造方法
JP2008195672A (ja) * 2007-02-14 2008-08-28 Okayama Univ 経口摂取用組成物及び経口摂取用組成物の製造方法
JP4822291B2 (ja) * 2008-03-14 2011-11-24 財団法人宮崎県産業支援財団 肝線維化抑制剤
TWI370736B (en) * 2008-12-31 2012-08-21 Ind Tech Res Inst Pharmaceutical composition for treating hepatitis b and heath food for inhibiting hepatitis b virus
CN101822372A (zh) * 2009-03-05 2010-09-08 财团法人工业技术研究院 用以治疗b型肝炎的药学组合物与抑制b型肝炎病毒的保健食品
CN101507730B (zh) * 2009-03-26 2011-01-26 复旦大学 表没食子儿茶素没食子酸酯与柔红霉素的组合物及其应用

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022080846A1 (ko) * 2020-10-13 2022-04-21 서울대학교병원 플라본을 포함하는 섬유증의 예방 또는 치료용 조성물

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Publication number Publication date
PL2689777T3 (pl) 2018-08-31
CN103442709A (zh) 2013-12-11
JP2014508785A (ja) 2014-04-10
WO2012126178A3 (zh) 2012-11-22
RU2013146602A (ru) 2015-04-27
KR101981378B1 (ko) 2019-05-22
ES2668785T3 (es) 2018-05-22
AU2011362905B2 (en) 2015-11-12
KR20160143868A (ko) 2016-12-14
CA2830616C (en) 2017-02-21
CA2830616A1 (en) 2012-09-27
DK2689777T3 (en) 2018-05-22
CN103442709B (zh) 2018-10-19
EP2689777A4 (en) 2014-09-17
EP2689777A2 (en) 2014-01-29
NO2689777T3 (enExample) 2018-08-25
AU2011362905A1 (en) 2013-10-31
WO2012126178A2 (zh) 2012-09-27
RU2561688C2 (ru) 2015-08-27
JP6166251B2 (ja) 2017-07-19
SG193486A1 (en) 2013-10-30
EP2689777B1 (en) 2018-03-28

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