KR20130010461A - Il―23에 결합하는 피브로넥틴 기반 스캐폴드 도메인 단백질 - Google Patents
Il―23에 결합하는 피브로넥틴 기반 스캐폴드 도메인 단백질 Download PDFInfo
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- KR20130010461A KR20130010461A KR1020127024171A KR20127024171A KR20130010461A KR 20130010461 A KR20130010461 A KR 20130010461A KR 1020127024171 A KR1020127024171 A KR 1020127024171A KR 20127024171 A KR20127024171 A KR 20127024171A KR 20130010461 A KR20130010461 A KR 20130010461A
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| AU2007325838B2 (en) | 2006-11-22 | 2013-09-19 | Bristol-Myers Squibb Company | Targeted therapeutics based on engineered proteins for tyrosine kinases receptors, including IGF-IR |
| AU2009213141A1 (en) | 2008-02-14 | 2009-08-20 | Bristol-Myers Squibb Company | Targeted therapeutics based on engineered proteins that bind EGFR |
| AR071874A1 (es) | 2008-05-22 | 2010-07-21 | Bristol Myers Squibb Co | Proteinas de dominio de armazon basadas en fibronectina multivalentes |
| TWI496582B (zh) | 2008-11-24 | 2015-08-21 | 必治妥美雅史谷比公司 | 雙重專一性之egfr/igfir結合分子 |
| JO3244B1 (ar) | 2009-10-26 | 2018-03-08 | Amgen Inc | بروتينات ربط مستضادات il – 23 البشرية |
| TW201138808A (en) * | 2010-05-03 | 2011-11-16 | Bristol Myers Squibb Co | Serum albumin binding molecules |
| JP6023703B2 (ja) | 2010-05-26 | 2016-11-09 | ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company | 改善された安定性を有するフィブロネクチンをベースとする足場タンパク質 |
| PT2635601T (pt) | 2010-11-04 | 2016-09-27 | Boehringer Ingelheim Int | Anticorpos anti-il-23 |
| US9260496B2 (en) | 2010-12-22 | 2016-02-16 | Bristol-Myers Squibb Company | Fibronectin based scaffold domain proteins that bind IL-23 |
| SI2697257T1 (sl) | 2011-04-13 | 2017-02-28 | Bristol-Myers Squibb Company | FC fuzijski proteini, ki vsebujejo nove linkerje ali razmestitve |
| WO2012158678A1 (en) | 2011-05-17 | 2012-11-22 | Bristol-Myers Squibb Company | Methods for maintaining pegylation of polypeptides |
| ES2848531T3 (es) | 2011-05-17 | 2021-08-10 | Bristol Myers Squibb Co | Métodos mejorados para la selección de proteínas de unión |
| EP2773659A2 (en) | 2011-10-31 | 2014-09-10 | Bristol-Myers Squibb Company | Fibronectin binding domains with reduced immunogenicity |
| US20140302999A1 (en) * | 2011-11-03 | 2014-10-09 | Magdalena Leszczyniecka | Method for determination of pharmacological properties of recombinant proteins |
| EP4039275A1 (en) | 2012-05-03 | 2022-08-10 | Boehringer Ingelheim International GmbH | Anti-il-23p19 antibodies |
| RS65556B1 (sr) | 2012-09-13 | 2024-06-28 | Bristol Myers Squibb Co | Proteini domena skele na bazi fibronektina koji vezuju miostatin |
| CZ2012829A3 (cs) | 2012-11-23 | 2014-06-11 | Biotechnologický Ústav Av Čr, V.V.I. | Polypeptidy pro léčbu autoimunitních chorob založenou na blokaci receptoru pro lidský cytokin IL-23 |
| EP2951206A2 (en) * | 2013-02-01 | 2015-12-09 | Bristol-Myers Squibb Company | Fibronectin based scaffold proteins |
| ES2814558T3 (es) * | 2013-02-06 | 2021-03-29 | Bristol Myers Squibb Co | Proteínas de dominio de fibronectina tipo III con solubilidad mejorada |
| ES2751735T3 (es) | 2013-02-12 | 2020-04-01 | Bristol Myers Squibb Co | Métodos de replegado de proteínas a elevado pH |
| EP3129401B1 (en) * | 2014-03-20 | 2019-06-12 | Bristol-Myers Squibb Company | Serum albumin-binding fibronectin type iii domains |
| US10507241B2 (en) | 2014-07-24 | 2019-12-17 | Boehringer Ingelheim International Gmbh | Biomarkers useful in the treatment of IL-23A related diseases |
| EA039598B9 (ru) | 2014-09-03 | 2022-03-10 | Бёрингер Ингельхайм Интернациональ Гмбх | Соединение, нацеленное на ил-23а и фно-альфа, и его применение |
| IL307578A (en) | 2015-02-04 | 2023-12-01 | Boehringer Ingelheim Int | Methods of treating inflammatory diseases |
| CN108290941A (zh) | 2015-09-23 | 2018-07-17 | 百时美施贵宝公司 | 快解离速率的血清白蛋白结合性纤连蛋白iii型结构域 |
| WO2017053619A1 (en) * | 2015-09-23 | 2017-03-30 | Bristrol-Myers Squibb Company | Glypican-3binding fibronectin based scafflold molecules |
| JP6872797B2 (ja) * | 2015-12-29 | 2021-05-19 | 国立大学法人東京工業大学 | 標的結合ペプチドの安定化方法 |
| TWI897843B (zh) * | 2017-05-03 | 2025-09-21 | 美商必治妥美雅史谷比公司 | 結合至肌肉生長抑制素以纖維連接蛋白為主之支架結構域蛋白質的穩定調配物 |
| WO2020176478A1 (en) | 2019-02-25 | 2020-09-03 | The University Of Chicago | Methods and compositions for treating inflammatory and autoimmune conditions with ecm-affinity peptides linked to anti-inflammatory agents |
| EP3789049A1 (en) * | 2019-09-06 | 2021-03-10 | QGel SA | Method for obtaining healthy intestinal organoids |
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2011
- 2011-02-16 BR BR112012019881A patent/BR112012019881A2/pt not_active IP Right Cessation
- 2011-02-16 SG SG2012058517A patent/SG183215A1/en unknown
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- 2011-02-16 KR KR1020127024171A patent/KR20130010461A/ko not_active Withdrawn
- 2011-02-16 WO PCT/US2011/024959 patent/WO2011103105A1/en not_active Ceased
- 2011-02-16 US US13/579,204 patent/US8927693B2/en active Active
- 2011-02-16 JP JP2012553974A patent/JP2013520426A/ja active Pending
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015080508A1 (ko) * | 2013-11-29 | 2015-06-04 | 일진엘이디(주) | 유전체층을 가진 발광 다이오드 |
Also Published As
| Publication number | Publication date |
|---|---|
| EA201270713A1 (ru) | 2013-01-30 |
| TWI508736B (zh) | 2015-11-21 |
| US8927693B2 (en) | 2015-01-06 |
| HK1179276A1 (en) | 2013-09-27 |
| EP2536757A1 (en) | 2012-12-26 |
| BR112012019881A2 (pt) | 2017-06-27 |
| AR080229A1 (es) | 2012-03-21 |
| EP2536757B1 (en) | 2015-03-25 |
| CA2790329A1 (en) | 2011-08-25 |
| CL2012002296A1 (es) | 2013-01-11 |
| US9714281B2 (en) | 2017-07-25 |
| AU2011218243A1 (en) | 2012-10-04 |
| US20150274806A1 (en) | 2015-10-01 |
| MX2012009050A (es) | 2012-09-07 |
| TW201130501A (en) | 2011-09-16 |
| WO2011103105A1 (en) | 2011-08-25 |
| TN2012000372A1 (en) | 2014-01-30 |
| SG183215A1 (en) | 2012-09-27 |
| JP2013520426A (ja) | 2013-06-06 |
| ZA201206969B (en) | 2015-06-24 |
| CN102762591A (zh) | 2012-10-31 |
| US20130012436A1 (en) | 2013-01-10 |
| PE20130041A1 (es) | 2013-01-28 |
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