KR20120061086A - 조직 인자 경로 저해제에 대한 앱타머 및 출혈 장애 치료제로서의 이의 용도 - Google Patents
조직 인자 경로 저해제에 대한 앱타머 및 출혈 장애 치료제로서의 이의 용도 Download PDFInfo
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| US20070166741A1 (en) | 1998-12-14 | 2007-07-19 | Somalogic, Incorporated | Multiplexed analyses of test samples |
| US7947447B2 (en) | 2007-01-16 | 2011-05-24 | Somalogic, Inc. | Method for generating aptamers with improved off-rates |
| JP5714505B2 (ja) | 2008-12-22 | 2015-05-07 | ノヴォ ノルディスク アー／エス | 組織因子経路阻害因子に対する抗体 |
| EP2673364A1 (en) * | 2011-02-11 | 2013-12-18 | Baxter International Inc | Aptamers to tissue factor pathway inhibitor and their use as bleeding disorder therapeutics |
| KR20140066977A (ko) * | 2011-06-08 | 2014-06-03 | 미에드지나로도위 인스티투트 바이오로지 모레쿠라네지 아이 코모르코웨즈 | 서열-특이적 조작된 리보뉴클레아제 ｈ 및 ｄｎａ－ｒｎａ 하이브리드 결합 단백질의 서열 선호도를 측정하는 방법 |
| AU2013235567A1 (en) * | 2012-03-22 | 2014-10-09 | Baxalta GmbH | Aptamers to tissue factor pathway inhibitor and their use as bleeding disorder therapeutics |
| DE102012020496A1 (de) | 2012-10-18 | 2014-04-24 | Charité - Universitätsmedizin Berlin | Biomarker zur Diagnostik und Behandlung von Neurofibromatose Typ 1 |
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| US10457743B2 (en) | 2013-07-19 | 2019-10-29 | Novo Nordisk A/S | Antibodies recognizing the N-terminal part of tissue factor pathway inhibitor capable of eliciting pro-coagulant activity |
| WO2015035305A1 (en) | 2013-09-09 | 2015-03-12 | Somalogic, Inc. | Pdgf and vegf aptamers having improved stability and their use in treating pdgf and vegf mediated diseases and disorders |
| US11181534B2 (en) | 2014-04-04 | 2021-11-23 | Bloodworks | Routine laboratory and point-of-care (POC) testing for hemostasis |
| SG10202100131WA (en) * | 2015-06-23 | 2021-02-25 | Childrens Hospital Philadelphia | Modified factor ix, and compositions, methods and uses for gene transfer to cells, organs and tissues |
| US20170232079A1 (en) * | 2015-10-06 | 2017-08-17 | Kieu Hoang | Method of manufacturing prothrombin complex concentrate from fraction iii and non-prothrombin complex concentrate from fraction iv |
| CN108368509B (zh) | 2015-12-04 | 2022-03-22 | 全药工业株式会社 | 改善了血中滞留性的抗il－17适体 |
| CN112442127A (zh) * | 2019-08-29 | 2021-03-05 | 苏州康宁杰瑞生物科技有限公司 | 针对tfpi的单克隆抗体 |
| CN115792231B (zh) * | 2022-11-04 | 2023-07-25 | 中拓生物有限公司 | 一种基于凝血酶适配体调节的酶级联反应的DNase I生物传感器 |
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| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US6239116B1 (en) | 1994-07-15 | 2001-05-29 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US6429199B1 (en) | 1994-07-15 | 2002-08-06 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules for activating dendritic cells |
| US5981471A (en) * | 1997-02-06 | 1999-11-09 | Entremed, Inc. | Compositions and methods for inhibiting cellular proliferation |
| AU738513B2 (en) | 1997-02-28 | 2001-09-20 | University Of Iowa Research Foundation, The | Use of nucleic acids containing unmethylated CpG dinucleotide in the treatment of LPS-associated disorders |
| US6426334B1 (en) | 1997-04-30 | 2002-07-30 | Hybridon, Inc. | Oligonucleotide mediated specific cytokine induction and reduction of tumor growth in a mammal |
| CA2302805A1 (en) | 1997-09-05 | 1999-03-11 | The Regents Of The University Of California | Use of immunostimulatory oligonucleotides for preventing or reducing antigen-stimulated, granulocyte-mediated inflammation |
| DE69940623D1 (de) * | 1998-11-09 | 2009-04-30 | Eiken Chemical | Prozess zur Synthetisierung von Nukleinsäure |
| US6514948B1 (en) | 1999-07-02 | 2003-02-04 | The Regents Of The University Of California | Method for enhancing an immune response |
| WO2003102212A2 (en) * | 2002-05-31 | 2003-12-11 | Regents Of The University Of Minnesota | In vitro evaluation of nucleic acid ligands |
| US7250496B2 (en) * | 2002-11-14 | 2007-07-31 | Rosetta Genomics Ltd. | Bioinformatically detectable group of novel regulatory genes and uses thereof |
| EP1919499A2 (en) | 2005-07-29 | 2008-05-14 | Universiteit van Maastricht | Regulation of tissue factor activity by protein s and tissue factor pathway inhibitor |
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| ES2655589T3 (es) | 2018-02-20 |
| EP2467167A1 (en) | 2012-06-27 |
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| AU2010284329A1 (en) | 2012-03-29 |
| RU2012110221A (ru) | 2013-09-27 |
| BR112012003806A2 (pt) | 2016-11-16 |
| CN102869385A (zh) | 2013-01-09 |
| IL218048A0 (en) | 2012-04-30 |
| NZ598557A (en) | 2013-08-30 |
| IN2012DN01984A (enExample) | 2015-07-24 |
| MX2012002133A (es) | 2013-02-15 |
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| AU2010284329B2 (en) | 2015-04-16 |
| US8252913B2 (en) | 2012-08-28 |
| EP2467167B1 (en) | 2017-08-16 |
| SG178408A1 (en) | 2012-03-29 |
| CA2770762A1 (en) | 2011-02-24 |
| JP2013502218A (ja) | 2013-01-24 |
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