KR20110098009A - Ｃｈｋ1 억제제와 시클로덱스트린의 조성물 - Google Patents
Ｃｈｋ1 억제제와 시클로덱스트린의 조성물 Download PDFInfo
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- KR20110098009A KR20110098009A KR1020117017995A KR20117017995A KR20110098009A KR 20110098009 A KR20110098009 A KR 20110098009A KR 1020117017995 A KR1020117017995 A KR 1020117017995A KR 20117017995 A KR20117017995 A KR 20117017995A KR 20110098009 A KR20110098009 A KR 20110098009A
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- A61K31/4965—Non-condensed pyrazines
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Landscapes
- Health & Medical Sciences (AREA)
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- Hematology (AREA)
- Inorganic Chemistry (AREA)
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- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
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| US11020363B2 (en) | 2009-05-29 | 2021-06-01 | Cydex Pharmaceuticals, Inc. | Injectable nitrogen mustard compositions comprising a cyclodextrin derivative and methods of making and using the same |
| EP2434886B1 (en) | 2009-05-29 | 2019-10-16 | CyDex Pharmaceuticals, Inc. | Injectable melphalan compositions comprising a cyclodextrin derivative and methods of making and using the same |
| GB201008005D0 (en) | 2010-05-13 | 2010-06-30 | Sentinel Oncology Ltd | Pharmaceutical compounds |
| EP2758052B9 (en) * | 2011-09-18 | 2019-03-27 | Euro-Celtique S.A. | Pharmaceutical composition comprising an HDAC inhibitor and a cyclopolysaccharide |
| EP2578582A1 (en) | 2011-10-03 | 2013-04-10 | Respivert Limited | 1-Pyrazolyl-3-(4-((2-anilinopyrimidin-4-yl)oxy)napththalen-1-yl)ureas as p38 MAP kinase inhibitors |
| PE20142355A1 (es) | 2011-10-03 | 2015-01-10 | Respivert Ltd | 1-pirazolil-3-(4-((2-anilinopirimidin-4-il)oxi)naftalen-1-il)ureas como inhibidores de proteinas cinasas activadas por mitogeno p38 |
| AR092790A1 (es) | 2012-02-01 | 2015-05-06 | Euro Celtique Sa | Derivados bencimidazolicos del acido hidroxamico |
| WO2013155485A2 (en) * | 2012-04-13 | 2013-10-17 | Alessia Fornoni | Method of using cyclodextrin |
| AU2014293013A1 (en) | 2013-07-26 | 2016-03-17 | Race Oncology Ltd. | Combinatorial methods to improve the therapeutic benefit of bisantrene |
| PT3357919T (pt) | 2014-02-14 | 2020-02-20 | Respivert Ltd | Compostos heterocíclicos aromáticos como compostos antiinflamatórios |
| GB201409485D0 (en) | 2014-05-28 | 2014-07-09 | Euro Celtique Sa | Pharmaceutical composition |
| GB201409471D0 (en) | 2014-05-28 | 2014-07-09 | Euro Celtique Sa | Pharmaceutical composition |
| GB201409488D0 (en) | 2014-05-28 | 2014-07-09 | Euro Celtique Sa | Pharmaceutical composition |
| US9890564B2 (en) | 2014-10-28 | 2018-02-13 | Sargent Manufacturing Company | Interconnected lock with direct drive for adjustable deadbolt to latchbolt spacing |
| JP2017155023A (ja) * | 2016-03-04 | 2017-09-07 | ジェイファーマ株式会社 | Ｌａｔ１阻害活性を有する芳香族アミノ酸誘導体を含有する注射剤 |
| EP3432880A4 (en) * | 2016-03-20 | 2019-12-11 | Asdera LLC | USE OF CYCLODEXTRINS TO REDUCE ENDOCYTOSIS IN MALIGNES AND NEURODEEGENERATIVE DISEASES |
| CA3040155C (en) | 2016-10-11 | 2024-01-16 | Euro-Celtique S.A. | Compound for use in the treatment of hodgkin lymphoma |
| EP3618825A4 (en) * | 2017-05-03 | 2021-01-20 | Cydex Pharmaceuticals, Inc. | COMPOSITION CONTAINING CYCLODEXTRIN AND BUSULFAN |
| GB201709403D0 (en) | 2017-06-13 | 2017-07-26 | Euro Celtique Sa | Compounds for treating sarcoma |
| GB201709406D0 (en) | 2017-06-13 | 2017-07-26 | Euro-Cletique S A | Compounds for treating TNBC |
| GB201709402D0 (en) | 2017-06-13 | 2017-07-26 | Euro Celtique Sa | Compounds for treating t-pll |
| GB201709405D0 (en) | 2017-06-13 | 2017-07-26 | Euro Celtique Sa | Compounds for treating ovarian cancer |
| JP2020535235A (ja) | 2017-09-28 | 2020-12-03 | アスデラ エルエルシー | リン脂質の調節異常が関与する疾患および障害におけるシクロデキストリンの使用 |
| CN109078005B (zh) * | 2018-08-07 | 2021-11-26 | 江苏领航生物科技有限公司 | 一种白消安组合物及其制备方法和应用 |
| JP2022522928A (ja) | 2018-12-18 | 2022-04-21 | ムンディファーマ・インターナショナル・コーポレーション・リミテッド | 多発性骨髄腫を治療するための化合物 |
| AU2024265078A1 (en) | 2023-05-04 | 2025-12-11 | Revolution Medicines, Inc. | Combination therapy for a ras related disease or disorder |
| WO2024246220A1 (en) * | 2023-05-31 | 2024-12-05 | Institut National de la Santé et de la Recherche Médicale | Methods and compositions for treating lung cancer |
| WO2025034702A1 (en) | 2023-08-07 | 2025-02-13 | Revolution Medicines, Inc. | Rmc-6291 for use in the treatment of ras protein-related disease or disorder |
| WO2025080946A2 (en) | 2023-10-12 | 2025-04-17 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2025171296A1 (en) | 2024-02-09 | 2025-08-14 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2025217307A1 (en) | 2024-04-09 | 2025-10-16 | Revolution Medicines, Inc. | Methods for predicting response to a ras(on) inhibitor and combination therapies |
| WO2025240847A1 (en) | 2024-05-17 | 2025-11-20 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2025255438A1 (en) | 2024-06-07 | 2025-12-11 | Revolution Medicines, Inc. | Methods of treating a ras protein-related disease or disorder |
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| DE3346123A1 (de) * | 1983-12-21 | 1985-06-27 | Janssen Pharmaceutica, N.V., Beerse | Pharmazeutische praeparate von in wasser schwerloeslichen oder instabilen arzneistoffen und verfahren zu ihrer herstellung |
| HU193933B (en) * | 1984-06-08 | 1987-12-28 | Nitrokemia Ipartelepek | Herbicide or plant growth stimulating agent comprising beta-cyclodextrin complex of benzolsulphonylurea derivative and process for preparing the active substances |
| IE62095B1 (en) * | 1988-03-29 | 1994-12-14 | Univ Florida | Pharmaceutical formulations for parenteral use |
| US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
| GB9001987D0 (en) | 1990-01-29 | 1990-03-28 | Janssen Pharmaceutica Nv | Improved cyclodextrin based erythropietin formulation |
| US5602112A (en) | 1992-06-19 | 1997-02-11 | Supergen, Inc. | Pharmaceutical formulation |
| US6046177A (en) | 1997-05-05 | 2000-04-04 | Cydex, Inc. | Sulfoalkyl ether cyclodextrin based controlled release solid pharmaceutical formulations |
| CA2320772A1 (en) * | 1998-02-23 | 1999-08-26 | Cyclops, Ehf. | High-energy cyclodextrin complexes |
| MXPA02012909A (es) | 2000-07-24 | 2004-05-05 | Boehringer Ingelheim Pharma | Formulaciones mejoradas de dosis oral de 1-(5-ter-butil -2-p-tiolil2h -pirazol-3 -il)-3-(4-2 (2-morfolin-4-il -etoxi) -naftalen -1-il) -urea. |
| UA76977C2 (en) | 2001-03-02 | 2006-10-16 | Icos Corp | Aryl- and heteroaryl substituted chk1 inhibitors and their use as radiosensitizers and chemosensitizers |
| WO2003015828A1 (en) * | 2001-08-20 | 2003-02-27 | Boehringer Ingelheim Pharmaceuticals, Inc. | Parenteral formulations of 1-(5-tert-butyl-2-p-tolyl-2h-pryrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea and a cyclodextrin |
| SE0201658D0 (sv) * | 2002-05-31 | 2002-05-31 | Astrazeneca Ab | Immediate release pharmaceutical formulation |
| MXPA06003110A (es) * | 2003-09-17 | 2006-06-20 | Icos Corp | Uso de inhibidores de chk1 para controlar la proliferacion celular. |
| KR20050039573A (ko) * | 2003-10-23 | 2005-04-29 | 주식회사 태평양 | 티오우레아계 유도체의 용해성과 생체이용률이 개선된약제학적 조성물 |
| PL1869020T3 (pl) * | 2005-03-29 | 2011-05-31 | Icos Corp | Pochodne heteroarylomocznika użyteczne w hamowaniu działania CHK1 |
| CN1813739A (zh) | 2005-11-25 | 2006-08-09 | 王颖 | 一种注射用盐酸纳美芬冻干粉针制剂 |
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| CN101528215B (zh) | 2011-10-19 |
| WO2008067027A2 (en) | 2008-06-05 |
| WO2008067027A3 (en) | 2009-04-16 |
| US20100022512A1 (en) | 2010-01-28 |
| AU2007325576A1 (en) | 2008-06-05 |
| IL197869A (en) | 2013-11-28 |
| SV2009003227A (es) | 2010-02-04 |
| BRPI0717460A2 (pt) | 2013-12-24 |
| MA30872B1 (fr) | 2009-11-02 |
| CA2673483C (en) | 2014-04-08 |
| CN101528215A (zh) | 2009-09-09 |
| EP2063879A2 (en) | 2009-06-03 |
| JP2010506942A (ja) | 2010-03-04 |
| TN2009000146A1 (en) | 2010-10-18 |
| NO20091544L (no) | 2009-06-10 |
| UA95310C2 (ru) | 2011-07-25 |
| MY150649A (en) | 2014-02-14 |
| US8455471B2 (en) | 2013-06-04 |
| KR20090065537A (ko) | 2009-06-22 |
| CO6180503A2 (es) | 2010-07-19 |
| CR10680A (es) | 2009-10-13 |
| MX2009004214A (es) | 2009-05-11 |
| NZ575394A (en) | 2012-01-12 |
| CA2673483A1 (en) | 2008-06-05 |
| EA200900571A1 (ru) | 2009-12-30 |
| ZA200902670B (en) | 2010-06-30 |
| AU2007325576B2 (en) | 2013-01-10 |
| IL197869A0 (en) | 2009-12-24 |
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