KR20110090911A - 포스파티딜이노시톨-3-키나아제 (ｐｉ3ｋ) 억제제 및 ｍｔｏｒ 억제제의 조합물 - Google Patents

포스파티딜이노시톨-3-키나아제 (ｐｉ3ｋ) 억제제 및 ｍｔｏｒ 억제제의 조합물 Download PDF

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KR20110090911A
KR20110090911A KR1020117009771A KR20117009771A KR20110090911A KR 20110090911 A KR20110090911 A KR 20110090911A KR 1020117009771 A KR1020117009771 A KR 1020117009771A KR 20117009771 A KR20117009771 A KR 20117009771A KR 20110090911 A KR20110090911 A KR 20110090911A
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substituted
unsubstituted
mtor
hydrogen
compound
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카를로스 가르시아-에체베리아
소뵈르-미셀 마이라
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노파르티스 아게
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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  • Neurology (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
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  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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  • Virology (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020117009771A 2008-10-31 2009-10-29 포스파티딜이노시톨-3-키나아제 (ｐｉ3ｋ) 억제제 및 ｍｔｏｒ 억제제의 조합물 Ceased KR20110090911A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08168044 2008-10-31
EP08168044.9 2008-10-31

Publications (1)

Publication Number Publication Date
KR20110090911A true KR20110090911A (ko) 2011-08-10

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KR1020117009771A Ceased KR20110090911A (ko) 2008-10-31 2009-10-29 포스파티딜이노시톨-3-키나아제 (ｐｉ3ｋ) 억제제 및 ｍｔｏｒ 억제제의 조합물

Country Status (12)

Country Link
US (3) US20110195966A1 (https=)
EP (1) EP2349275B1 (https=)
JP (4) JP2012506898A (https=)
KR (1) KR20110090911A (https=)
CN (2) CN105030784A (https=)
AU (1) AU2009309616B2 (https=)
BR (1) BRPI0921802A8 (https=)
CA (1) CA2736361C (https=)
ES (1) ES2627677T3 (https=)
MX (1) MX2011004585A (https=)
RU (2) RU2538683C2 (https=)
WO (1) WO2010049481A1 (https=)

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KR20210158019A (ko) 2020-06-23 2021-12-30 주식회사 온코빅스 포스파티딜이노시톨 3-키나제(pi3k) 억제제로써 pten 과오종 증후군에 의한 종양 세포의 성장 또는 증식을 억제하는데 유용한 신규한 피리미딘 유도체 및 이의 약제학적으로 허용가능한 염, 및 이를 유효성분으로 함유하는 약제학적 조성물

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WO2014160328A1 (en) 2013-03-13 2014-10-02 The Board Of Regents Of The University Of Texas System Mtor inhibitors for prevention of intestinal polyp growth
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CN103483345B (zh) * 2013-09-25 2016-07-06 中山大学 Pi3k激酶抑制剂、包含其的药物组合物及其应用
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210158019A (ko) 2020-06-23 2021-12-30 주식회사 온코빅스 포스파티딜이노시톨 3-키나제(pi3k) 억제제로써 pten 과오종 증후군에 의한 종양 세포의 성장 또는 증식을 억제하는데 유용한 신규한 피리미딘 유도체 및 이의 약제학적으로 허용가능한 염, 및 이를 유효성분으로 함유하는 약제학적 조성물

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CA2736361C (en) 2017-10-10
BRPI0921802A2 (pt) 2016-09-27
JP2017002058A (ja) 2017-01-05
AU2009309616A2 (en) 2011-07-07
AU2009309616A1 (en) 2010-05-06
US20110195966A1 (en) 2011-08-11
BRPI0921802A8 (pt) 2018-03-13
CA2736361A1 (en) 2010-05-06
CN105030784A (zh) 2015-11-11
RU2011121508A (ru) 2012-12-10
JP2012506898A (ja) 2012-03-22
EP2349275A1 (en) 2011-08-03
JP2015013883A (ja) 2015-01-22
JP2018197243A (ja) 2018-12-13
WO2010049481A1 (en) 2010-05-06
EP2349275B1 (en) 2017-03-08
CN102202668A (zh) 2011-09-28
RU2538683C2 (ru) 2015-01-10
RU2014115188A (ru) 2015-10-20
ES2627677T3 (es) 2017-07-31
AU2009309616B2 (en) 2014-02-13
US20180133226A1 (en) 2018-05-17
MX2011004585A (es) 2011-06-01
US20160136175A1 (en) 2016-05-19

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