KR20110017431A - 신규한 트리사이클릭 화합물 - Google Patents

신규한 트리사이클릭 화합물 Download PDF

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Publication number
KR20110017431A
KR20110017431A KR1020117000497A KR20117000497A KR20110017431A KR 20110017431 A KR20110017431 A KR 20110017431A KR 1020117000497 A KR1020117000497 A KR 1020117000497A KR 20117000497 A KR20117000497 A KR 20117000497A KR 20110017431 A KR20110017431 A KR 20110017431A
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South Korea
Prior art keywords
optionally substituted
alkyl
heterocyclyl
alkylene
cycloalkyl
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KR1020117000497A
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English (en)
Korean (ko)
Inventor
닐 위샤트
마리아 에이. 아지리아디
데이비드 제이. 칼더우드
안나 엠. 에릭손
브라이언 에이. 피아멩고
크리스틴 이. 프랭크
마이클 프리드맨
던 엠. 조지
에릭 알. 고드켄
나탄 에스. 조셉슨
비친 씨. 리
마이클 제이. 모리트코
켄트 디. 스튜어트
제프리 더블유. 보스
그리어 에이. 월리스
루 왕
케빈 알. 월러
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아보트 러보러터리즈
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41415363&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR20110017431(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 아보트 러보러터리즈 filed Critical 아보트 러보러터리즈
Publication of KR20110017431A publication Critical patent/KR20110017431A/ko
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Transplantation (AREA)
  • Psychiatry (AREA)
KR1020117000497A 2008-06-10 2009-06-09 신규한 트리사이클릭 화합물 Withdrawn KR20110017431A (ko)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US13159908P 2008-06-10 2008-06-10
US13160208P 2008-06-10 2008-06-10
US61/131,602 2008-06-10
US61/131,599 2008-06-10
US19015908P 2008-08-26 2008-08-26
US61/190,159 2008-08-26
US20106408P 2008-12-05 2008-12-05
US61/201,064 2008-12-05

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020167035162A Division KR101718384B1 (ko) 2008-06-10 2009-06-09 신규한 트리사이클릭 화합물

Publications (1)

Publication Number Publication Date
KR20110017431A true KR20110017431A (ko) 2011-02-21

Family

ID=41415363

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020117000497A Withdrawn KR20110017431A (ko) 2008-06-10 2009-06-09 신규한 트리사이클릭 화합물
KR1020167035162A Active KR101718384B1 (ko) 2008-06-10 2009-06-09 신규한 트리사이클릭 화합물

Family Applications After (1)

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KR1020167035162A Active KR101718384B1 (ko) 2008-06-10 2009-06-09 신규한 트리사이클릭 화합물

Country Status (36)

Country Link
US (5) US8962629B2 (https=)
EP (2) EP2299821B1 (https=)
JP (2) JP5748659B2 (https=)
KR (2) KR20110017431A (https=)
CN (2) CN104592231A (https=)
AR (1) AR072086A1 (https=)
AU (1) AU2009257602B2 (https=)
BR (1) BRPI0915374B1 (https=)
CA (2) CA2727032C (https=)
CL (1) CL2010001426A1 (https=)
CO (1) CO6382083A2 (https=)
CR (1) CR20160007A (https=)
CY (1) CY1117165T1 (https=)
DK (1) DK2299821T3 (https=)
DO (2) DOP2010000382A (https=)
EC (1) ECSP10010657A (https=)
ES (1) ES2559403T3 (https=)
HR (1) HRP20160098T1 (https=)
HU (1) HUE028347T2 (https=)
IL (1) IL209434A0 (https=)
ME (1) ME02340B (https=)
MX (1) MX2010013557A (https=)
MY (1) MY161369A (https=)
NO (1) NO20101688A1 (https=)
NZ (1) NZ623922A (https=)
PE (2) PE20110223A1 (https=)
PL (1) PL2299821T3 (https=)
PT (1) PT2299821E (https=)
RS (1) RS54560B1 (https=)
RU (2) RU2545023C9 (https=)
SI (1) SI2299821T1 (https=)
TW (3) TWI449703B (https=)
UA (1) UA106045C2 (https=)
UY (1) UY31881A (https=)
WO (1) WO2009152133A1 (https=)
ZA (1) ZA201008562B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20180081523A (ko) * 2015-10-16 2018-07-16 애브비 인코포레이티드 (3S,4R)-3-에틸-4-(3H-이미다조[1,2-a]피롤로[2,3-e]-피라진-8-일)-N-(2,2,2-트리플루오로에틸)피롤리딘-1-카복스아미드 및 이의 고체상 형태의 제조 방법

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JP5748659B2 (ja) 2008-06-10 2015-07-15 アッヴィ・インコーポレイテッド 新規な三環式化合物
AU2010237859A1 (en) * 2009-04-14 2011-11-03 Astellas Pharma Inc. Fused pyrrolopyridine derivative
EP2421867B1 (en) * 2009-04-20 2015-09-02 Auspex Pharmaceuticals, Llc Piperidine inhibitors of janus kinase 3
WO2011011594A2 (en) * 2009-07-23 2011-01-27 Shriners Hospitals For Children Intracellular toll-like receptors pathways and axonal degeneration
US8361962B2 (en) * 2009-07-27 2013-01-29 Roche Palo Alto Llc Tricyclic inhibitors of JAK
EP2475667A1 (en) 2009-09-10 2012-07-18 F. Hoffmann-La Roche AG Inhibitors of jak
MX2012002385A (es) 2009-09-21 2012-04-02 Hoffmann La Roche Inhibidores macrociclicos de cinasa janus.
JP5728487B2 (ja) 2009-10-29 2015-06-03 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ 三環式ヘテロ環化合物
KR20120102724A (ko) * 2009-12-01 2012-09-18 아보트 러보러터리즈 신규한 트리사이클릭 화합물
PE20121336A1 (es) 2009-12-01 2012-11-03 Abbvie Inc Nuevos compuestos triciclicos
US8329705B2 (en) 2009-12-30 2012-12-11 Arqule, Inc. Substituted triazolo-pyrazine compounds
EP2523957A1 (en) * 2010-01-12 2012-11-21 F. Hoffmann-La Roche AG Tricyclic heterocyclic compounds, compositions and methods of use thereof
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CN102118968A (zh) 2011-07-06
MY161369A (en) 2017-04-14
BRPI0915374A2 (pt) 2015-08-04
EP2299821A1 (en) 2011-03-30
HRP20160098T1 (hr) 2016-02-26

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