KR20110004455A - 항-ｆｌｔ３ 항체 - Google Patents

항-ｆｌｔ３ 항체 Download PDF

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Publication number
KR20110004455A
KR20110004455A KR1020107026790A KR20107026790A KR20110004455A KR 20110004455 A KR20110004455 A KR 20110004455A KR 1020107026790 A KR1020107026790 A KR 1020107026790A KR 20107026790 A KR20107026790 A KR 20107026790A KR 20110004455 A KR20110004455 A KR 20110004455A
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KR
South Korea
Prior art keywords
ser
val
thr
leu
gly
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Ceased
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KR1020107026790A
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English (en)
Korean (ko)
Inventor
이웬 리
단 루
데이비드 수르굴라지
제임스 알. 톤라
Original Assignee
임클론 엘엘씨
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41092183&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR20110004455(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 임클론 엘엘씨 filed Critical 임클론 엘엘씨
Publication of KR20110004455A publication Critical patent/KR20110004455A/ko
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
KR1020107026790A 2008-05-30 2009-05-28 항-ｆｌｔ３ 항체 Ceased KR20110004455A (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US13053908P 2008-05-30 2008-05-30
US13039508P 2008-05-30 2008-05-30
US13039408P 2008-05-30 2008-05-30
US61/130,394 2008-05-30
US61/130,539 2008-05-30
US61/130,395 2008-05-30

Publications (1)

Publication Number Publication Date
KR20110004455A true KR20110004455A (ko) 2011-01-13

Family

ID=41092183

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020107026790A Ceased KR20110004455A (ko) 2008-05-30 2009-05-28 항-ｆｌｔ３ 항체

Country Status (18)

Country Link
US (3) US20110091470A1 (cg-RX-API-DMAC10.html)
EP (1) EP2300500A1 (cg-RX-API-DMAC10.html)
JP (1) JP2011521647A (cg-RX-API-DMAC10.html)
KR (1) KR20110004455A (cg-RX-API-DMAC10.html)
CN (1) CN102046659A (cg-RX-API-DMAC10.html)
AR (1) AR071891A1 (cg-RX-API-DMAC10.html)
AU (1) AU2009260517B2 (cg-RX-API-DMAC10.html)
BR (1) BRPI0912173A2 (cg-RX-API-DMAC10.html)
CA (1) CA2726522A1 (cg-RX-API-DMAC10.html)
CL (1) CL2009001277A1 (cg-RX-API-DMAC10.html)
EA (1) EA201071421A1 (cg-RX-API-DMAC10.html)
IL (1) IL209142A0 (cg-RX-API-DMAC10.html)
MX (1) MX2010013144A (cg-RX-API-DMAC10.html)
NZ (1) NZ588791A (cg-RX-API-DMAC10.html)
PE (1) PE20091963A1 (cg-RX-API-DMAC10.html)
TW (1) TWI374032B (cg-RX-API-DMAC10.html)
WO (1) WO2009155015A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA201008024B (cg-RX-API-DMAC10.html)

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Publication number Publication date
EA201071421A1 (ru) 2011-08-30
AU2009260517B2 (en) 2012-12-06
CA2726522A1 (en) 2009-12-23
US20110091470A1 (en) 2011-04-21
AU2009260517A1 (en) 2009-12-23
ZA201008024B (en) 2012-04-25
NZ588791A (en) 2012-05-25
TW201010722A (en) 2010-03-16
US8071099B2 (en) 2011-12-06
CL2009001277A1 (es) 2010-10-08
PE20091963A1 (es) 2010-01-15
WO2009155015A1 (en) 2009-12-23
IL209142A0 (en) 2011-01-31
JP2011521647A (ja) 2011-07-28
US20110008355A1 (en) 2011-01-13
BRPI0912173A2 (pt) 2016-07-26
EP2300500A1 (en) 2011-03-30
US20090297529A1 (en) 2009-12-03
AR071891A1 (es) 2010-07-21
MX2010013144A (es) 2010-12-21
TWI374032B (en) 2012-10-11
CN102046659A (zh) 2011-05-04

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