KR20100126536A - 벤조-융합된 다이옥신 유도체의 제조방법 - Google Patents

벤조-융합된 다이옥신 유도체의 제조방법 Download PDF

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Publication number
KR20100126536A
KR20100126536A KR1020107023449A KR20107023449A KR20100126536A KR 20100126536 A KR20100126536 A KR 20100126536A KR 1020107023449 A KR1020107023449 A KR 1020107023449A KR 20107023449 A KR20107023449 A KR 20107023449A KR 20100126536 A KR20100126536 A KR 20100126536A
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KR
South Korea
Prior art keywords
formula
compound
group
yield
organic
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KR1020107023449A
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English (en)
Korean (ko)
Inventor
스콧 에이. 발렌타인
라우라 레아니
Original Assignee
얀센 파마슈티카 엔.브이.
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Application filed by 얀센 파마슈티카 엔.브이. filed Critical 얀센 파마슈티카 엔.브이.
Publication of KR20100126536A publication Critical patent/KR20100126536A/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
KR1020107023449A 2008-03-26 2008-03-26 벤조-융합된 다이옥신 유도체의 제조방법 KR20100126536A (ko)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2008/058247 WO2009120192A2 (en) 2008-03-26 2008-03-26 Process for the preparation of benzo-fused heteroaryl derivatives

Publications (1)

Publication Number Publication Date
KR20100126536A true KR20100126536A (ko) 2010-12-01

Family

ID=40351717

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020107023449A KR20100126536A (ko) 2008-03-26 2008-03-26 벤조-융합된 다이옥신 유도체의 제조방법

Country Status (13)

Country Link
EP (1) EP2280951A2 (es)
JP (1) JP2011517448A (es)
KR (1) KR20100126536A (es)
CN (1) CN101981023A (es)
AU (1) AU2008353492A1 (es)
BR (1) BRPI0822396A2 (es)
CA (1) CA2719402A1 (es)
EA (1) EA201071121A1 (es)
EC (1) ECSP10010498A (es)
IL (1) IL208223A0 (es)
MX (1) MX2010010597A (es)
WO (1) WO2009120192A2 (es)
ZA (1) ZA201007610B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY147767A (en) 2004-06-16 2013-01-31 Janssen Pharmaceutica Nv Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders
CA2609185A1 (en) 2005-05-20 2006-11-30 Ahmed F. Abdel-Magid Process for preparation of sulfamide derivatives
US8691867B2 (en) 2005-12-19 2014-04-08 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction
US8937096B2 (en) 2005-12-19 2015-01-20 Janssen Pharmaceutica Nv Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder
US8497298B2 (en) 2005-12-19 2013-07-30 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels
EP2026790A2 (en) 2006-05-19 2009-02-25 Janssen Pharmaceutica, N.V. Co-therapy for the treatment of epilepsy and related disorders
MX2011000090A (es) * 2008-06-23 2011-03-02 Janssen Pharmaceutica Nv Forma cristalina de (2s)-(-)-n-(6-cloro-2,3-dihidro-benzo[1,4]diox in-2-ilmetil)sulfamida.
US8815939B2 (en) 2008-07-22 2014-08-26 Janssen Pharmaceutica Nv Substituted sulfamide derivatives
CA2850015A1 (en) * 2011-09-29 2013-04-04 Janssen Pharmaceutica Nv Improved process for the preparation of sulfamide derivatives
JP2014528953A (ja) * 2011-09-29 2014-10-30 ヤンセン ファーマシューティカ エヌ．ベー． スルファミド誘導体の調製プロセス

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5120758A (en) * 1991-02-08 1992-06-09 Ciba-Geigy Corporation Certain benzodioxole, benzodioxane and benzodioxepin derivatives useful as 5-lipoxygenase inhibitors
MY147767A (en) * 2004-06-16 2013-01-31 Janssen Pharmaceutica Nv Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders

Also Published As

Publication number Publication date
IL208223A0 (en) 2010-12-30
ZA201007610B (en) 2012-04-25
AU2008353492A1 (en) 2009-10-01
CA2719402A1 (en) 2009-10-01
EA201071121A1 (ru) 2011-04-29
MX2010010597A (es) 2010-10-25
EP2280951A2 (en) 2011-02-09
JP2011517448A (ja) 2011-06-09
WO2009120192A2 (en) 2009-10-01
BRPI0822396A2 (pt) 2019-09-24
ECSP10010498A (es) 2010-10-30
CN101981023A (zh) 2011-02-23
WO2009120192A3 (en) 2010-01-21

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